Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lia Signaevskaia"'
Autor:
Christina M. Termini, Amara Pang, Tiancheng Fang, Martina Roos, Vivian Y. Chang, Yurun Zhang, Nicollette J. Setiawan, Lia Signaevskaia, Michelle Li, Mindy M. Kim, Orel Tabibi, Paulina K. Lin, Joshua P. Sasine, Avradip Chatterjee, Ramachandran Murali, Heather A. Himburg, John P. Chute
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Ionizing radiation and chemotherapy deplete haematopoietic stem cells and damage the vascular niche. Here the authors show that irradiation induces SEMA3A secretion from bone marrow endothelial cells (ECs), inducing EC apoptosis via NRP1 and that NRP
Externí odkaz:
https://doaj.org/article/1bc7079a69604192ab5c5cd6cd2c1289
Autor:
Kathleen M. Scully, Reyhaneh Lahmy, Lia Signaevskaia, Roman Sasik, Rachel Medal, Heejung Kim, Randall French, Brian James, Yifan Wu, Andrew M. Lowy, Pamela Itkin-Ansari
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 2, Pp 181-198 (2018)
Background & Aims: Oncogenic mutations in KRAS, coupled with inactivation of p53, CDKN2A/p16INK4A, and SMAD4, drive progression of pancreatic ductal adenocarcinoma (PDA). Overexpression of MYC and deregulation of retinoblastoma (RB) further promote c
Externí odkaz:
https://doaj.org/article/7aad93be4d8148b1b1f6f1e79e906dae
Autor:
Jacqueline M Grible, Tess Leftwich, Amy L Olex, Alex K Duong, Nicole Hairr, Narmeen S Rashid, Timothy M Smith, Lia Signaevskaia, David C Boyd, Mikhail G Dozmorov, Joshua C Harrell
Publikováno v:
Cancer Research. 82:P3-09
Breast cancers that are hormone receptor negative, such that they do not express the estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER2), are known as triple-negative breast cancer (TNBC), and are pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::963c0a68d8b7e2704ef08d0fb73d9510
https://doi.org/10.1158/1538-7445.sabcs21-p3-09-06
https://doi.org/10.1158/1538-7445.sabcs21-p3-09-06
Autor:
Yurun Zhang, Tiancheng Fang, Katherine Pohl, Martina Roos, John P. Chute, Peter A. Scott, Anna Patricia L. Javier, Vivian Y. Chang, Paulina K. Lin, Amara Pang, Christina M. Termini, Heather A. Himburg, Xiao Yan, Liman Zhao, Lia Signaevskaia, Mamle Quarmyne, Jenny Kan
Publikováno v:
Blood
Chemotherapy and irradiation cause DNA damage to hematopoietic stem cells (HSCs), leading to HSC depletion and dysfunction and the risk of malignant transformation over time. Extrinsic regulation of HSC DNA repair is not well understood, and therapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f57c1b35fce4e9e1cfbbb26c5d3f6b
https://doi.org/10.1182/blood.2020005895
https://doi.org/10.1182/blood.2020005895
Autor:
Yurun Zhang, Tiancheng Fang, Vivian Y. Chang, Martina Roos, Lia Signaevskaia, Heather A. Himburg, Paulina K. Lin, Amara Pang, Mindy M. Kim, Joshua P. Sasine, Christina M. Termini, Orel Tabibi, Avradip Chatterjee, Michelle Li, Ramachandran Murali, John P. Chute, Nicollette J Setiawan
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Ionizing radiation and chemotherapy deplete hematopoietic stem cells and damage the vascular niche wherein hematopoietic stem cells reside. Hematopoietic stem cell regeneration requires signaling from an intact bone marrow (BM) vascular niche, but th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e062fda3492e51b9c9ca50666fe28924
http://europepmc.org/articles/PMC8635308
http://europepmc.org/articles/PMC8635308
Autor:
Pamela Itkin-Ansari, Roman Sasik, Yifan Wu, Reyhaneh Lahmy, Rachel Medal, Randall French, Kathleen M. Scully, Lia Signaevskaia, Brian P. James, Heejung Kim, Andrew M. Lowy
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 2, Pp 181-198 (2018)
Background & Aims: Oncogenic mutations in KRAS, coupled with inactivation of p53, CDKN2A/p16INK4A, and SMAD4, drive progression of pancreatic ductal adenocarcinoma (PDA). Overexpression of MYC and deregulation of retinoblastoma (RB) further promote c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98c45226df98d6e1d93c00ec8b17e20
http://www.sciencedirect.com/science/article/pii/S2352345X18300717
http://www.sciencedirect.com/science/article/pii/S2352345X18300717