Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lia Panman"'
Autor:
Rachel E. Hardy, Injae Chung, Yizhou Yu, Samantha H. Y. Loh, Nobuhiro Morone, Clement Soleilhavoup, Marco Travaglio, Riccardo Serreli, Lia Panman, Kelvin Cain, Judy Hirst, Luis M. Martins, Marion MacFarlane, Kenneth R. Pryde
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-17 (2023)
Abstract Antipsychotic drugs are the mainstay of treatment for schizophrenia and provide adjunct therapies for other prevalent psychiatric conditions, including bipolar disorder and major depressive disorder. However, they also induce debilitating ex
Externí odkaz:
https://doaj.org/article/cda70abcbca34ff6acad1a69f18c9111
Autor:
Clement Soleilhavoup, Marco Travaglio, Kieran Patrick, Pedro Garção, Elangovan Boobalan, Youri Adolfs, Ruth V. Spriggs, Emma Moles-Garcia, Dalbir Dhiraj, Tony Oosterveen, Sarah L. Ferri, Ted Abel, Edward S. Brodkin, R. Jeroen Pasterkamp, Brian P. Brooks, Lia Panman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The mechanisms regulating midbrain dopaminergic innervation during development are unclear. Here, the authors showed that Nolz1 is required for axonal guidance of dopaminergic neurons during embryonic development of the mouse brain.
Externí odkaz:
https://doaj.org/article/a1e6f0aa3aeb4df3a70d891a709de121
Autor:
Lia Panman, Maria Papathanou, Ariadna Laguna, Tony Oosterveen, Nikolaos Volakakis, Dario Acampora, Idha Kurtsdotter, Takashi Yoshitake, Jan Kehr, Eliza Joodmardi, Jonas Muhr, Antonio Simeone, Johan Ericson, Thomas Perlmann
Publikováno v:
Cell Reports, Vol 8, Iss 4, Pp 1018-1025 (2014)
Distinct midbrain dopamine (mDA) neuron subtypes are found in the substantia nigra pars compacta (SNc) and the ventral tegmental area (VTA), but it is mainly SNc neurons that degenerate in Parkinson’s disease. Interest in how mDA neurons develop ha
Externí odkaz:
https://doaj.org/article/ba6aa9efcd9841008ff6c5b6521d0229
Autor:
Clement Soleilhavoup, Kieran Patrick, Ulrika Marklund, Emma Moles-Garcia, Lucie Combes-Soia, Peter Hohenstein, Rosa Peltrini, Marco Travaglio, Shahida Sheraz, Lia Panman, Pedro Garção, Tony Oosterveen, Valérie Labas
Publikováno v:
Stem Cell Reports
Stem Cell Reports, 16(11), 2718-2735. CELL PRESS
Stem Cell Reports, 16(11), 2718-2735. CELL PRESS
Summary In Parkinson’s disease (PD), substantia nigra (SN) dopaminergic (DA) neurons degenerate, while related ventral tegmental area (VTA) DA neurons remain relatively unaffected. Here, we present a methodology that directs the differentiation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d006543b9504297a169d6eb9abf3107
http://europepmc.org/articles/PMC8581055
http://europepmc.org/articles/PMC8581055
Autor:
Ruth V. Spriggs, R. Jeroen Pasterkamp, Lia Panman, Clement Soleilhavoup, Brian P. Brooks, Kieran Patrick, Emma Moles-Garcia, Marco Travaglio, Tony Oosterveen, Pedro Garção, Youri Adolfs, Sarah L. Ferri, Edward S. Brodkin, Ted Abel, Elangovan Boobalan, Dalbir Dhiraj
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Funder: Vetenskapsrådet (Swedish Research Council); doi: https://doi.org/10.13039/501100004359
Midbrain dopaminergic (DA) axons make long longitudinal projections towards the striatum. Despite the importance of DA striatal innervation, processe
Midbrain dopaminergic (DA) axons make long longitudinal projections towards the striatum. Despite the importance of DA striatal innervation, processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7719617e46edf41275329bf56aaed13
https://doi.org/10.1038/s41467-020-16947-6
https://doi.org/10.1038/s41467-020-16947-6
Autor:
Sara Cimini, Tiziana Borsello, Daniel C. Maddison, Mariaelena Repici, Pedro Garção, Kathryn S. Lilley, Kornelis Straatman, Lia Panman, Flaviano Giorgini, Éva M. Szegö, Tiago F. Outeiro, Bhavini Patel, Mahdieh Hassanjani
Publikováno v:
Molecular Neurobiology
Mutations in the gene encoding DJ-1 are associated with autosomal recessive forms of Parkinson’s disease (PD). DJ-1 plays a role in protection from oxidative stress, but how it functions as an “upstream” oxidative stress sensor and whether this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9f86dfa3fd6f13ca2f5435e191c646
https://doi.org/10.1007/s12035-018-1084-y
https://doi.org/10.1007/s12035-018-1084-y
Autor:
Daniel Aberdam, Peleg Hasson, Eshkar Nir, Anna Altshuler, Ruby Shalom-Feuerstein, Swarnabh Bhattacharya, Dalbir Dhiraj, Maroun Khreish, Chen Luxenburg, Beatrice Tiosano, Lia Panman, Laura Serror
Publikováno v:
Stem Cells (Dayton, Ohio)
Mutations in key transcription factors SOX2 and P63 were linked with developmental defects and postnatal abnormalities such as corneal opacification, neovascularization, and blindness. The latter phenotypes suggest that SOX2 and P63 may be involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eccf11140f9a122857090948c0594f7
https://pubmed.ncbi.nlm.nih.gov/30548157
https://pubmed.ncbi.nlm.nih.gov/30548157
Autor:
Johan Ericson, Lawrence W. Stanton, Lia Panman, Zhanna Alekseenko, Nigel Kee, Jamie Mong, Thomas Perlmann
Publikováno v:
Stem Cells. 32:609-622
An important goal in stem cell biology is to develop methods for efficient generation of clinically interesting cell types from relevant stem cell populations. This is particularly challenging for different types of neurons of the central nervous sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b42fb4031fc1aed52c24464b3a271ca
https://doi.org/10.1002/stem.1585
https://doi.org/10.1002/stem.1585
Autor:
Eliza Joodmardi, Jessica M. Silvaggi, Banafsheh Kadkhodaei, Karin Wallis, Bruce M. Spiegelman, Lia Panman, Thomas Perlmann, Nikolaos Volakakis
Publikováno v:
Proceedings of the National Academy of Sciences. 107:12317-12322
Induced expression of neuroprotective genes is essential for maintaining neuronal integrity after stressful insults to the brain. Here we show that NR4A nuclear orphan receptors are induced after excitotoxic and oxidative stress in neurons, up-regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a86af359d09ec608339e3ea1cbaf57b
https://doi.org/10.1073/pnas.1007088107
https://doi.org/10.1073/pnas.1007088107
Publikováno v:
Development. 131:3401-3410
Epithelial-mesenchymal feedback signaling is the key to diverse organogenetic processes such as limb bud development and branching morphogenesis in kidney and lung rudiments. This study establishes that the BMP antagonist gremlin (Grem1) is essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a79d963584706b506b76448d3b864e
https://doi.org/10.1242/dev.01251
https://doi.org/10.1242/dev.01251