Výsledky vyhledávání

Akademický článek

Downregulation of Plasma Membrane Ca2+ ATPase driven by tyrosine hydroxylase-Gal4 reduces Drosophila lifespan independently of effects in neurons

Autor: Brenda Erhardt, Lia Frenkel, María Silvina Marcora, María Isabel Farías, Carina Cintia Ferrari, Fernando Juan Pitossi, María Celeste Leal

Publikováno v: Fly, Vol 17, Iss 1 (2023)

In Drosophila melanogaster, several Gal4 drivers are used to direct gene/RNAi expression to different dopaminergic neuronal clusters. We previously developed a fly model of Parkinson’s disease, in which dopaminergic neurons had elevated cytosolic C

Externí odkaz: https://doaj.org/article/c52956268f8d4ae18f4f75c88cee9332

Zobrazit plný text záznamu

Akademický článek

Organization of Circadian Behavior Relies on Glycinergic Transmission

Autor: Lia Frenkel, Nara I. Muraro, Andrea N. Beltrán González, María S. Marcora, Guillermo Bernabó, Christiane Hermann-Luibl, Juan I. Romero, Charlotte Helfrich-Förster, Eduardo M. Castaño, Cristina Marino-Busjle, Daniel J. Calvo, M. Fernanda Ceriani

Publikováno v: Cell Reports, Vol 19, Iss 1, Pp 72-85 (2017)

The small ventral lateral neurons (sLNvs) constitute a central circadian pacemaker in the Drosophila brain. They organize daily locomotor activity, partly through the release of the neuropeptide pigment-dispersing factor (PDF), coordinating the actio

Externí odkaz: https://doaj.org/article/b828befe10e04b1ba42b3b1afe8e0517

Zobrazit plný text záznamu

Plasma membrane calcium ATPase downregulation in dopaminergic neurons alters cellular physiology and motor behaviour in Drosophila melanogaster

Autor: Brenda Erhardt, María Celeste Leal, Pablo Alejandro Bochicchio, Christian Höcht, María Isabel Farías, Carina Cintia Ferrari, Miguel Ángel Allo, Diego Hernán Bodin, Lia Frenkel, María Silvina Marcora, Berenice Anabel Silva, Fernando Juan Pitossi

Publikováno v: European Journal of Neuroscience. 54:5915-5931

The accumulation of Ca2+ and its subsequent increase in oxidative stress is proposed to be involved in selective dysfunctionality of dopaminergic neurons, the main cell type affected in Parkinson's disease. To test the in vivo impact of Ca2+ incremen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db9ae6298714361ad0503f61cc09009
https://doi.org/10.1111/ejn.15401

Zobrazit plný text záznamu

Author response for 'Plasma membrane calcium ATPase downregulation in dopaminergic neurons alters cellular physiology and motor behaviour in Drosophila melanogaster'

Autor: Brenda Erhardt, Christian Höcht, Pablo Alejandro Bochicchio, María Isabel Farías, Maria Celeste Leal, Lia Frenkel, Miguel Ángel Allo, Berenice Silva, Diego Hernán Bodin, María Silvina Marcora, Fernando Juan Pitossi, Carina Cintia Ferrari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221023c0b33c528b1ee30a3ab43414cb
https://doi.org/10.1111/ejn.15401/v2/response1

Zobrazit plný text záznamu

High-frequency neuronal bursting is essential for circadian and sleep behaviors in drosophila

Autor: Karina Cerredo, Florencia Fernandez-Chiappe, Carina Celeste Colque, Nara I. Muraro, Lia Frenkel, Bryan Hahm, Ana Ricciuti, María Fernanda Ceriani

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
J Neurosci

Circadian rhythms have been extensively studied in Drosophila; however, still little is known about how the electrical properties of clock neurons are specified. We have performed a behavioral genetic screen through the downregulation of candidate io

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3a3d91fc911a390c60d743df51ad5f
https://www.jneurosci.org/content/41/4/689

Zobrazit plný text záznamu

Orcokinin neuropeptides regulate reproduction in the fruit fly, Drosophila melanogaster

Autor: Mariano Volonté, John Ewer, Lia Frenkel, Angelina Palacios-Muñoz, Valeria Silva, Sheila Ons

Publikováno v: Insect biochemistry and molecular biology. 139

In animals, neuropeptidergic signaling is essential for the regulation of survival and reproduction. In insects, Orcokinins are poorly studied, despite their high level of conservation among different orders. In particular, there are currently no rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b774a03f4508b92a74a90101997524
https://pubmed.ncbi.nlm.nih.gov/34742859

Zobrazit plný text záznamu

High frequency neuronal bursting is essential for circadian and sleep behaviors in Drosophila

Autor: Ana Ricciuti, María Fernanda Ceriani, Carina Celeste Colque, Lia Frenkel, Nara I. Muraro, Karina Cerredo, Florencia Fernandez-Chiappe, Bryan Hahm

Circadian rhythms have been extensively studied in Drosophila, however, still little is known about how the electrical properties of clock neurons are specified. We have performed a behavioral genetic screen through the downregulation of candidate io

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b0a1bee4c3bed3ba4f3991485ce1b2

Zobrazit plný text záznamu

'Plasma Membrane Calcium Atpase downregulation in dopaminergic neurons alters cellular physiology and behavior in Drosophila melanogaster'

Autor: Christian Höcht, María Celeste Leal, María Isabel Farías, Miguel Ángel Allo, Diego Hernán Bodin, Lia Frenkel, María Silvina Marcora, Carina Cintia Ferrari, Pablo Alejandro Bochicchio, Berenice Anabel Silva, Brenda Erhardt, Fernando Juan Pitossi, Eduardo M Castaño

Accumulation of calcium is proposed to account for selective dopaminergic neuron (DN) dysfunctionality, a characteristic of Parkinson’s Disease (PD). To test the in vivo impact of calcium increment in DN physiology we downregulated the Plasma Membr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ab2e7a4c1424d094dd27e7b2b2cd33
https://doi.org/10.1101/714147

Zobrazit plný text záznamu

The Underlying Genetics of

Autor: D Lorena, Franco, Lia, Frenkel, M Fernanda, Ceriani

Publikováno v: Physiology (Bethesda, Md.). 33(1)

Life is shaped by circadian clocks. This review focuses on how behavioral genetics in the fruit fly unveiled what is known today about circadian physiology. We will briefly summarize basic properties of the clock and focus on some clock-controlled be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76ef2b119cc48cd64e77ac1594d7a829
https://pubmed.ncbi.nlm.nih.gov/29212892

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání