Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lia Cynthia Garcia"'
Autor:
Lucía Gandolfi Donadío, James A. Kelley, Xiaoling Zhou, Lia Cynthia Garcia, Christopher C. Lai, Megan L. Peach, Nancy E. Lewin, Maria Julieta Comin, Peter M. Blumberg, Eleonora Elhalem
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:2971-2980
C1 domain-containing proteins, such as protein kinase C (PKC), have a central role in cellular signal transduction. Their involvement in many diseases, including cancer, cardiovascular disease, and immunological and neurological disorders has been ex
Autor:
Lucía Gandolfi Donadío, Marina Santos, Carlos Fernandez, Lia Cynthia Garcia, Hernán Orgueira, Cintia Carolina Checura, Maria Julieta Comin
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 114:441-446
Two new potential impurities of antiarrhythmic drug substance Dronedarone Hydrochloride together with debutyldronedarone were detected by LC?MS analysis during process development. A successful synthetic strategy for the synthesis of these potential
Autor:
Jessica S. Kelsey, Marina Santos, Timothy E. Esch, Collin S. Hill, Nancy E. Lewin, Megan L. Peach, Ella Mann, Victor E. Marquez, Lucía Gandolfi Donadío, Noemi Kedei, Raz Jelinek, Peter M. Blumberg, Maria Julieta Comin, Lia Cynthia Garcia, Sofiya Kolusheva, James A. Kelley, Jing Yang
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:3123-3140
The development of selective agents capable of discriminating between protein kinase C (PKC) isoforms and other diacylglycerol (DAG)-responsive C1 domain-containing proteins represents an important challenge. Recent studies have highlighted the role