Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Lia Baki"'
Autor:
Yu Xu, Tyler Hendon, Ganesh A. Thakur, Lia Baki, Junghoon Ha, Andreas Papapetropoulos, Diomedes E. Logothetis, Sumanta Garai, Leigh D. Plant, Takeharu Kawano
Publikováno v:
Journal of Biological Chemistry. 293:3546-3561
Inwardly rectifying potassium (Kir) channels establish and regulate the resting membrane potential of excitable cells in the heart, brain, and other peripheral tissues. Phosphatidylinositol 4,5-bisphosphate (PIP2) is a key direct activator of ion cha
Autor:
Kelsey S. Hideshima, Diomedes E. Logothetis, Jose M. Eltit, Jason Younkin, Lia Baki, Amr Ellaithy, Supriya A Gaitonde, Javier González-Maeso, Malgorzata Dukat, José L. Moreno, Rakesh H. Vekariya, Sneha Shah, Richard A. Glennon, Peter Drossopoulos
Publikováno v:
ACS Chemical Neuroscience. 7:1292-1299
Several pharmacophore models have been proposed for 5-HT2A serotonin receptor antagonists. These typically consist of two aromatic/hydrophobic moieties separated by a given distance from each other, and from a basic amine. Although specified distance
Autor:
Javier González-Maeso, José L. Moreno, Jason Younkin, Lia Baki, Jose M. Eltit, Adishesh Narahari, Diomedes E. Logothetis, Zhanna V. Vysotskaya, Stuart C. Sealfon, Miguel Fribourg, Gyu Park
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 468:775-793
We previously reported that co-expression of the Gi-coupled metabotropic glutamate receptor 2 (mGlu2R) and the Gq-coupled serotonin (5-HT) 2A receptor (2AR) in Xenopus oocytes (Fribourg et al. Cell 147:1011-1023, 2011) results in inverse cross-signal
Autor:
Junghoon, Ha, Yu, Xu, Takeharu, Kawano, Tyler, Hendon, Lia, Baki, Sumanta, Garai, Andreas, Papapetropoulos, Ganesh A, Thakur, Leigh D, Plant, Diomedes E, Logothetis
Publikováno v:
The Journal of biological chemistry. 293(10)
Inwardly rectifying potassium (Kir) channels establish and regulate the resting membrane potential of excitable cells in the heart, brain, and other peripheral tissues. Phosphatidylinositol 4,5-bisphosphate (PIP(2)) is a key direct activator of ion c
Autor:
Anna N. Bukiya, Catherine V. Osborn, Myung-Jin Oh, Irena Levitan, Alejandro M. Dopico, Lia Baki, Gregory B. Kowalsky, Avia Rosenhouse-Dantsker, Peter T. Toth, Guruprasad Kuntamallappanavar
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1848(10):2406-2413
Cholesterol is one of the major lipid components of membranes in mammalian cells. In recent years, cholesterol has emerged as a major regulator of ion channel function. The most common effect of cholesterol on ion channels in general and on inwardly
Publikováno v:
Biophysical Journal. 116:234a
Autor:
Graeme Milligan, Patricia Miranda-Azpiazu, Anastasios Georgakopoulos, Meng Cui, Ariel Ben-Ezra, Georgios Voloudakis, Nikolaos K. Robakis, Diomedes E. Logothetis, Aintzane García-Bea, Juan F. López-Giménez, Alexey Kozlenkov, Lia Baki, Javier González-Maeso, Jason Younkin, Yongchao Ge, José L. Moreno, Amanda K. Fakira, Jose A. Morón, J. Javier Meana
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
PMCID: PMC4819166.-- Moreno et al.
Heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors (GPCRs) can form multiprotein complexes (heteromers), which can alter the pharmacology and functions of the constituent receptors.
Heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors (GPCRs) can form multiprotein complexes (heteromers), which can alter the pharmacology and functions of the constituent receptors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870a4b456ac480c71abf6a58f578a748
https://europepmc.org/articles/PMC4819166/
https://europepmc.org/articles/PMC4819166/
Autor:
Yacob Gomez-Llorente, José L. Chávez, Edgar Leal-Pinto, Qiong-Yao Tang, Iban Ubarretxena-Belandia, Rahul Mahajan, Zhe Zhang, Diomedes E. Logothetis, Lia Baki, Shobana Sundaram, Tatyana Ivanova-Nikolova
Publikováno v:
Journal of Biological Chemistry. 285:39790-39800
Kir3 channels control heart rate and neuronal excitability through GTP-binding (G) protein and phosphoinositide signaling pathways. These channels were the first characterized effectors of the βγ subunits of G proteins. Because we currently lack st
Autor:
Ravi Iyengar, Nikolaos K. Robakis, Radda Rusinova, Yibang Chen, Lia Baki, Anastasios Georgakopoulos, Ioannis E. Michailidis, Diomedes E. Logothetis
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 461:387-397
Phosphatidylinositol-4,5-bisphosphate [PI(4,5)P(2) or PIP(2)] is a direct modulator of a diverse array of proteins in eukaryotic cells. The functional integrity of transmembrane proteins, such as ion channels and transporters, is critically dependent
Publikováno v:
Cardiovascular Research. 88:93-100
We assessed regulation of volume-sensitive Cl(-) current (I(Cl,swell)) by endothelin-1 (ET-1) and characterized the signalling pathway responsible for its activation in rabbit atrial and ventricular myocytes.ET-1 elicited I(Cl,swell) under isosmotic