Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lia A. Michaels"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Bacteria in natural environments and infections are often found in cell aggregates suspended in polymer-rich solutions, and aggregation can promote bacterial survival and stress resistance. One aggregation mechanism, called depletion aggregation, is
Externí odkaz:
https://doaj.org/article/a33e8591870a4262b1f8c900dd6fd291
Autor:
Amelia K. Schmidt, Alexa D. Fitzpatrick, Caleb M. Schwartzkopf, Dominick R. Faith, Laura K. Jennings, Alison Coluccio, Devin J. Hunt, Lia A. Michaels, Aviv Hargil, Qingquan Chen, Paul L. Bollyky, David W. Dorward, Jenny Wachter, Patricia A. Rosa, Karen L. Maxwell, Patrick R. Secor
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Pseudomonas aeruginosa is an opportunistic pathogen that causes infections in a variety of settings. Many P. aeruginosa isolates are infected by filamentous Pf bacteriophage integrated into the bacterial chromosome as a prophage. Pf virions
Externí odkaz:
https://doaj.org/article/be036206c0534feea60671006a1e5924
Autor:
Patrick R. Secor, Elizabeth B. Burgener, M. Kinnersley, Laura K. Jennings, Valery Roman-Cruz, Medeea Popescu, Jonas D. Van Belleghem, Naomi Haddock, Conner Copeland, Lia A. Michaels, Christiaan R. de Vries, Qingquan Chen, Julie Pourtois, Travis J. Wheeler, Carlos E. Milla, Paul L. Bollyky
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Pf bacteriophage are temperate phages that infect the bacterium Pseudomonas aeruginosa, a major cause of chronic lung infections in cystic fibrosis (CF) and other settings. Pf and other temperate phages have evolved complex, mutualistic relationships
Externí odkaz:
https://doaj.org/article/0fbbcd58934c4e5bade6db1d83a8f046
Autor:
Patrick R. Secor, Laura K. Jennings, Lia A. Michaels, Johanna M. Sweere, Pradeep K. Singh, William C. Parks, Paul L. Bollyky
Publikováno v:
Microbial Cell, Vol 3, Iss 1, Pp 49-52 (2015)
Pseudomonas aeruginosa is an opportunistic bacterial pathogen associated with many types of chronic infection. At sites of chronic infection, such as the airways of people with cystic fibrosis (CF), P. aeruginosa forms biofilm-like aggregates. These
Externí odkaz:
https://doaj.org/article/9947fe8bc36649ca85927b3a70b49de3
Autor:
Camilla D. de Mattos, Dominick R. Faith, Artem A. Nemudryi, Amelia K. Schmidt, DeAnna C. Bublitz, Lauren Hammond, Margie A. Kinnersley, Caleb M. Schwartzkopf, Autumn J. Robinson, Alex Joyce, Lia A. Michaels, Robert S. Brzozowski, Alison Coluccio, Denghui David Xing, Jumpei Uchiyama, Laura K. Jennings, Prahathees Eswara, Blake Wiedenheft, Patrick R. Secor
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Monitoring the extracellular environment for danger signals is a critical aspect of cellular survival. However, the danger signals released by dying bacteria and the mechanisms bacteria use for threat assessment remain largely unexplored. Here , we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91f3f81c828a4624761293a32127df15
https://doi.org/10.1073/pnas.2216430120
https://doi.org/10.1073/pnas.2216430120
Autor:
Camilla D. de Mattos, Artem A. Nemudryi, Dominick Faith, DeAnna C. Bublitz, Lauren Hammond, Margie A. Kinnersley, Caleb M. Schwartzkopf, Autumn J. Robinson, Alex Joyce, Lia A. Michaels, Robert S. Brzozowski, Alison Coluccio, Denghui David Xing, Jumpei Uchiyama, Laura K. Jennings, Prahathees Eswara, Blake Wiedenheft, Patrick R. Secor
When eukaryotic cells are killed by pathogenic microorganisms, damage-associated and pathogen-associated signals are generated that alert other cells of nearby danger. Bacteria can detect the death of their kin; however, how bacteria make threat asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a2e722528e8120bbb958095aed05eff
https://doi.org/10.1101/2022.04.01.486733
https://doi.org/10.1101/2022.04.01.486733
Autor:
D. Rodriguez, Amanda A. Kidman, Peter Jorth, Lia A. Michaels, Erin K. Cassin, Boo Shan Tseng, Melissa C. Schofield, Elizabeth A. Campbell
Publikováno v:
Molecular microbiologyREFERENCES. 116(2)
During decades-long infections in the cystic fibrosis (CF) airway, Pseudomonas aeruginosa undergoes selection. One bacterial genetic adaptation often observed in CF isolates is mucA mutations. MucA inhibits the sigma factor AlgU. Mutations in mucA le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b078aec5df626a629138b5bab40da0
https://pubmed.ncbi.nlm.nih.gov/33905139
https://pubmed.ncbi.nlm.nih.gov/33905139
Autor:
Melissa C. Schofield, Daniela Rodriguez, Amanda A. Kidman, Erin K. Cassin, Lia A. Michaels, Elizabeth A. Campbell, Peter A. Jorth, Boo Shan Tseng
During decades-long infections in the cystic fibrosis (CF) airway, Pseudomonas aeruginosa undergoes selection. One bacterial genetic adaptation often observed in CF isolates is mucA mutations. MucA inhibits the sigma factor AlgU. Mutations in mucA le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce8e76257ea02948788450076a2fe78c
https://doi.org/10.1101/2020.08.17.253617
https://doi.org/10.1101/2020.08.17.253617
Autor:
Lia A. Michaels, Elizabeth A. Campbell, Erin K. Cassin, D. Rodriguez, Amanda A. Kidman, Peter Jorth, Melissa C. Schofield, B. Tseng
Publikováno v:
Journal of Cystic Fibrosis. 20:S208
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::145540e0ca33ed8b72c498fc2209c68a
https://doi.org/10.1016/s1569-1993(21)01866-x
https://doi.org/10.1016/s1569-1993(21)01866-x
Bacteria causing chronic infections are generally observed living in cell aggregates suspended in polymer-rich host secretions, and bacterial phenotypes induced by aggregated growth may be key factors in chronic infection pathogenesis. Bacterial aggr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7798bec6005a7171a725194cc0dc337
https://europepmc.org/articles/PMC6196481/
https://europepmc.org/articles/PMC6196481/