Zobrazeno 1 - 5
of 5
pro vyhledávání: '"LiRen Tu"'
Autor:
Brenda R. Grimes, Roger B. Slee, Nazmul Huda, David Gilley, LiRen Tu, Liang Cheng, Alison M. Bates
Publikováno v:
Molecular Carcinogenesis. 55:842-852
A critical function of the telomere is to disguise chromosome ends from cellular recognition as double strand breaks, thereby preventing aberrant chromosome fusion events. Such chromosome end-to-end fusions are known to initiate genomic instability v
Real-Time, Non-instrusive Instrumentation and Monitoring of Standards-Based Event-Based Applications
Publikováno v:
ISORC
This paper presents an approach for non-intrusively instrumenting standards-based event-based middle-ware. The approach has been realized in an open-source tool called Component Port Monitor (CPM). CPM uses dynamic binary instrumentation as a means t
Autor:
Michelle Dean, Ruiqiong Ye, Jeffrey D. Hamill, Eiji Kubota, Huong Muzik, Chris T. Williamson, LiRen Tu, Susan P. Lees-Miller, Alexander C. Klimowicz, Bruce C. McKay, Anthony M. Magliocco, D. Gwyn Bebb, David Gilley
Publikováno v:
EMBO Molecular Medicine
Poly-ADP ribose polymerase (PARP) inhibitors have shown promise in the treatment of human malignancies characterized by deficiencies in the DNA damage repair proteins BRCA1 and BRCA2 and preclinical studies have demonstrated the potential effectivene
Autor:
LiRen, Tu, Nazmul, Huda, Brenda R, Grimes, Roger B, Slee, Alison M, Bates, Liang, Cheng, David, Gilley
Publikováno v:
Molecular carcinogenesis. 55(5)
A critical function of the telomere is to disguise chromosome ends from cellular recognition as double strand breaks, thereby preventing aberrant chromosome fusion events. Such chromosome end-to-end fusions are known to initiate genomic instability v
Autor:
Radina Droumeva, Nazmul Huda, Satoshi Abe, Ryan R. Brinkman, Peter M. Lansdorp, Connie J. Eaves, David Gilley, Elizabeth A. Chavez, Nagarajan Kannan, Geraldine Aubert, Joanne T. Emerman, LiRen Tu
Publikováno v:
Stem Cell Reports
Stem Cell Reports, 1(1), 28-37. CELL PRESS
Stem Cell Reports, 1(1), 28-37. CELL PRESS
Telomeres are essential for genomic integrity, but little is known about their regulation in the normal human mammary gland. We now demonstrate that a phenotypically defined cell population enriched in luminal progenitors (LPs) is characterized by un