Suppression of chemotaxis by SSeCKS via scaffolding of phosphoinositol phosphates and the recruitment of the Cdc42 GEF, Frabin, to the leading edge.

Autor: Hyun-Kyung Ko, Li-wu Guo, Bing Su, Lingqiu Gao, Irwin H Gelman

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e111534 (2014)

Chemotaxis is controlled by interactions between receptors, Rho-family GTPases, phosphatidylinositol 3-kinases, and cytoskeleton remodeling proteins. We investigated how the metastasis suppressor, SSeCKS, attenuates chemotaxis. Chemotaxis activity in

Externí odkaz: https://doaj.org/article/61de1cbc098c408b944d283c47602022

Synergization of an endoplasmic reticulum-targeted iridium(III) photosensitizer with PD-L1 inhibitor for oral squamous cell carcinoma immunotherapy

Autor: Zhou, Jia-Ying, Shen, Qing-Hua, Hong, Xiao-Jing, Zhang, Wu-Ya, Su, Qiao, Li, Wu-Guo, Cheng, Bin, Tan, Cai-Ping, Wu, Tong

Publikováno v: In Chemical Engineering Journal 15 October 2023 474

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A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

Autor: Jan Hellemans, Hans Binder, Jean Thierry-Mieg, Joshua Xu, Djork-Arné Clevert, Peter Sykacek, Matthias Fischer, Youping Deng, Samir Lababidi, Ryan Peters, Hanlin Gao, Craig A. Praul, Meihua Gong, Jo Vandesompele, Haiqing Li, Wei Wang, Joaquín Dopazo, Shawn Levy, Yang Liao, John Zhang, Lee Thomas Szkotnicki, Paul Zumbo, Huixiao Hong, Weida Tong, Quan Zhen Li, E. Aubrey Thompson, Jennifer G. Catalano, Danielle Thierry-Mieg, Binsheng Gong, Wenwei Zhang, Wendell D. Jones, Min Jian, Dalila B. Megherbi, Lucille Rainbow, Robert Setterquist, Peng Li, Hong Fang, Javier Pérez-Florido, Xin Lu, Chen Zhao, Stephen J. Walker, Tao Qing, Marco Chierici, Yiming Zhou, Joseph Meehan, Christopher E. Mason, Eric D. Wieben, Mehdi Pirooznia, Liqing Wan, Bimeng Tu, Stan Letovsky, James C. Fuscoe, Sepp Hochreiter, Yoichi Gondo, Alicia Vela-Boza, Bridgett Green, Li Li, Zirui Dong, Weimin Cai, Geng Chen, Pedro Furió-Tarí, Andreas Scherer, Zhenqiang Su, Scott Schwartz, Charles Wang, Frank Staedtler, Jian Wang, Wenzhong Xiao, Yong Yang, Murray H. Brilliant, Wei Shi, Scott S. Auerbach, Matthew Tinning, Yongxiang Fang, Tingting Du, Meiwen Jia, Jiekun Xuan, Shiyong Li, Yan Li, Ying Yu, Adnan Derti, Ruchir R. Shah, Nadereh Jafari, Nancy Stralis-Pavese, Edward J. Oakeley, Jinhui Wang, Pierre R. Bushel, Jun Wang, Simon Lin, Joost H.M. van Delft, Francisco Javier López, Weigong Ge, Huan Gao, James C. Willey, Roger Perkins, Xin Xing Tan, Viswanath Devanarayan, Laure Sambourg, Zhiyu Peng, Po Yen Wu, Jianying Li, Philippe Rocca-Serra, Javier Santoyo-Lopez, Paweł P. Łabaj, David P. Kreil, Elia Stupka, John H. Phan, Heng Luo, Gary P. Schroth, Roderick V. Jensen, Thomas M. Blomquist, Russell D. Wolfinger, John F. Thompson, Wenqian Zhang, Nan Mei, Suzanne Kay, May D. Wang, Tzu Ming Chu, Jie Shen, Jiri Zavadil, Weihong Xu, Wenjun Bao, Akhilesh Pandey, Rong Chen, Leming Shi, Yutaka Suzuki, Todd M. Smith, Chao Guo, Zhuolin Gong, Feng Qian, Mario Fasold, Lei Guo, Ching-Wei Chang, Reagan Kelly, Ana Conesa, Yate Ching Yuan, Cesare Furlanello, Elisa Venturini, Zhan Ye, Yuanting Zheng, Jos C. S. Kleinjans, James Hadfield, Susanna-Assunta Sansone, Gordon K. Smyth, Li Wu Guo, Stan Gaj, Oliver Stegle, Yanyan Zhang, Tao Chen, Ye Yin, Anita Fernandez, Tieliu Shi, Charles D. Johnson, Baitang Ning, Fei Lu, Florian Caimet, Bing Mu, Jorge Gandara, Ke Zhang, Sheng Li, Xiwen Ma

Publikováno v: Nature biotechnology
Nature Biotechnology, 32(9), 903-914. Nature Publishing Group

We present primary results from the Sequencing Quality Control (SEQC) project, coordinated by the US Food and Drug Administration. Examining Illumina HiSeq, Life Technologies SOLiD and Roche 454 platforms at multiple laboratory sites using reference

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f574fbd57cb9cc567146ad9815046e12
https://doi.org/10.1038/nbt.2957

Cytotoxicity and inhibitory effects of low-concentration triclosan on adipogenic differentiation of human mesenchymal stem cells

Autor: Steven R. Bauer, Greg T. Nolen, Qiangen Wu, Jia-Long Fang, Helen Deng, Li-Wu Guo, Jessica LoSurdo, Leming Shi, Baitang Ning, Bridgett Green

Publikováno v: Toxicology and Applied Pharmacology. 262:117-123

Humans at all ages are continually exposed to triclosan (TCS), a widely used antimicrobial agent that can be found in many daily hygiene products, such as toothpastes and shampoos; however, the toxicological and biological effects of TCS in the human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff54523c2dcf92f9a2366a55b1f75594
https://doi.org/10.1016/j.taap.2012.04.024