Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Li-wen Ko"'
94
To maintain the development of their fishery sector, many countries enforce various subsidies to meet their domestic needs. Fishery resources are renewable resources, but people usually regard them as resources that will never run out and ove
To maintain the development of their fishery sector, many countries enforce various subsidies to meet their domestic needs. Fishery resources are renewable resources, but people usually regard them as resources that will never run out and ove
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/86061428193353492508
Coordinating orders between a manufacturer and retailers through price discounts and multiple orders
92
This study analyzes how to increase the profit and total cost of the manufacturer and retailers in a supply chain by order coordination, price discount and multiple orders. Order coordination considered in this thesis is between a manufacture
This study analyzes how to increase the profit and total cost of the manufacturer and retailers in a supply chain by order coordination, price discount and multiple orders. Order coordination considered in this thesis is between a manufacture
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/c3v8x2
Autor:
Li-Wen Ko1 ko.li-wen@mayo.edu, Rush, Toni1, Sahara, Naruhiko1,2, Kersh, Jay S.1, Easson, Colin1, DeTure, Michael1, Wen-Lang Lin1, Connor, Yamicia D.3, Yen, Shu-Hui C.1
Publikováno v:
Journal of Alzheimer's Disease. 2004, Vol. 6 Issue 6, p605-622. 18p. 1 Black and White Photograph, 8 Diagrams, 2 Charts, 1 Graph.
Publikováno v:
Neurobiology of Aging. 33:2306-2320
Epidemiological studies have shown that long-term treatment with statins decreases the risk of developing Alzheimer's disease. Statins have pleiotropic effects by lowering the concentration of isoprenoid intermediates. Although several studies have s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32b737b189bf71c98e7cbda331e7f6c
https://doi.org/10.1016/j.neurobiolaging.2011.10.020
https://doi.org/10.1016/j.neurobiolaging.2011.10.020
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 67:1084-1096
Filamentous alpha-synuclein (alpha-syn) aggregates form Lewy bodies (LBs), the neuropathologic hallmarks of Parkinson disease and related alpha-synucleinopathies. To model Lewy body-associated neurodegeneration, we generated transfectant 3D5 of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d45689cdfd1ab06a6df2cabb36a2f94
https://doi.org/10.1097/nen.0b013e31818c3618
https://doi.org/10.1097/nen.0b013e31818c3618
Autor:
Jennifer Hussey, Shu Hui C. Yen, Samuel Yen, Matthew J. Farrer, Colin Easson, John Hardy, Nitin D. Mehta, Li Wen Ko
Publikováno v:
Journal of Neurochemistry. 75:2546-2554
Linkage of alpha-synuclein (alpha-SN) mutations to familial Parkinson's disease (PD) and presence of alpha-SN as a major constituent of Lewy body in both sporadic and familial PD implicate alpha-SN abnormality in PD pathogenesis. Here we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f17cc91271779583a6a774dd255e0738
https://doi.org/10.1046/j.1471-4159.2000.0752546.x
https://doi.org/10.1046/j.1471-4159.2000.0752546.x
Autor:
Makio Takahashi, Shu Hui C. Yen, Jayanarayan Kulathingal, Li Wen Ko, Daniel Sevlever, Peizhou Jiang
Publikováno v:
European Journal of Neuroscience. 26:863-874
Intracellular accumulation of alpha-synuclein (alpha-Syn) as filamentous aggregates is a pathological feature shared by Parkinson's disease, dementia with Lewy bodies and multiple system atrophy, referred to as synucleinopathies. To understand the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd6c647ab93f79416078ea97b9ef8d0
https://doi.org/10.1111/j.1460-9568.2007.05736.x
https://doi.org/10.1111/j.1460-9568.2007.05736.x
Autor:
Li Wen Ko, Peter Davies, Takashi Ishizawa, Natalie Cookson, Marisol Espinoza, Dennis W. Dickson
Publikováno v:
Scopus-Elsevier
The CA2 sector of the hippocampus is relatively resistant to neurofibrillary tangles in aging and Alzheimer disease; however, some cases have selective neurofibrillary degeneration in CA2 with sparing of the more vulnerable CA1 sector. Cases such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098b4bfd7a1deef3e16d4346536369d8
https://doi.org/10.1093/jnen/61.12.1040
https://doi.org/10.1093/jnen/61.12.1040
Publikováno v:
Journal of Neurochemistry. 69:2026-2038
The degradation of different isoforms of human recombinant tau (R-tau; T39, T40, and T44) and fetal tau (F-tau) by cathepsin D (CD) was investigated. Gel electrophoresis and Coomassie Blue staining of different R-tau species digested at pH 3.5 showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b23396d4c6876ae0842c4e78d9606d6
https://doi.org/10.1046/j.1471-4159.1997.69052026.x
https://doi.org/10.1046/j.1471-4159.1997.69052026.x
Publikováno v:
The American Journal of Pathology. 161:1711-1722
Conditional expression systems for 4-repeat wild-type (WT) tau or the corresponding mutants V337M and R406W were established in human neuroglioma H4 cells to study the effect of tau mutations on the physicochemical properties of tau, and to develop a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f183d3f2ede62df3d46fd9b7556bd031
https://doi.org/10.1016/s0002-9440(10)64448-3
https://doi.org/10.1016/s0002-9440(10)64448-3