Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Li-qing Jin"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Previously, we reported that RhoA knockdown by morpholino antisense oligonucleotides (MOs), and enzymatic digestion of chondroitin sulfate proteoglycans (CSPGs) at the site of injury with chondroitinase ABC (ChABC), each can reduce retrograde neurona
Externí odkaz:
https://doaj.org/article/8ab27c06e866439facea1a3d62b1114a
Autor:
Guixin Zhang, Li-Qing Jin, William Rodemer, Jianli Hu, Zachary D. Root, Daniel M. Medeiros, Michael E. Selzer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Axon regrowth after spinal cord injury (SCI) is inhibited by several types of inhibitory extracellular molecules in the central nervous system (CNS), including chondroitin sulfate proteoglycans (CSPGs), which also are components of perineuronal nets
Externí odkaz:
https://doaj.org/article/9c41ccef149447e59f41956a4bce1fc4
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 9, Pp 1955-1956 (2022)
Externí odkaz:
https://doaj.org/article/cc37e70756734695ae6545ad34df4ffb
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Paralysis following spinal cord injury (SCI) is due to failure of axonal regeneration. It is believed that axon growth is inhibited by the presence of several types of inhibitory molecules in central nervous system (CNS), including the chondroitin su
Externí odkaz:
https://doaj.org/article/8c8a9bb4d8d748278aa0c91a80131f15
Publikováno v:
Cells, Vol 11, Iss 15, p 2320 (2022)
Axotomy in the CNS activates retrograde signals that can trigger regeneration or cell death. Whether these outcomes use different injury signals is not known. Local protein synthesis in axon tips plays an important role in axon retraction and regener
Externí odkaz:
https://doaj.org/article/6a3ce620adfc4bd9a9a73cbff0a1f09c
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
We previously reported that spinal cord transection (TX) in the lamprey causes mRNA to accumulate in the injured tips of large reticulospinal (RS) axons. We sought to determine whether this mRNA accumulation results from phosphorylation and transport
Externí odkaz:
https://doaj.org/article/c656e29d0acd4d6e84e1f959b926322e
Autor:
William Rodemer, Guixin Zhang, Isabelle Sinitsa, Jianli Hu, Li-qing Jin, Shuxin Li, Michael E. Selzer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Traumatic spinal cord injury (SCI) results in persistent functional deficits due to the lack of axon regeneration within the mammalian CNS. After SCI, chondroitin sulfate proteoglycans (CSPGs) inhibit axon regrowth via putative interactions with the
Externí odkaz:
https://doaj.org/article/5ea9d2603b5849fbaec125545284468b
Publikováno v:
Neurobiology of Disease, Vol 98, Iss , Pp 25-35 (2017)
Paralysis following spinal cord injury (SCI) is due to interruption of axons and their failure to regenerate. It has been suggested that the small GTPase RhoA may be an intracellular signaling convergence point for several types of growth-inhibiting
Externí odkaz:
https://doaj.org/article/80d0569f127f4df79a93e14bb5811bf7
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137670 (2015)
The sea lamprey has been used as a model for the study of axonal regeneration after spinal cord injury. Previous studies have suggested that, unlike developing axons in mammal, the tips of regenerating axons in lamprey spinal cord are simple in shape
Externí odkaz:
https://doaj.org/article/c128e7b80860428898b617dcef7f284c
Publikováno v:
Neural regeneration research. 17(9)