Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Li-min Mao"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2024)
Five muscarinic acetylcholine (mACh) receptor subtypes are divided into two classes: the M1 class (M1, M3, and M5) and the M2 class (M2 and M4). The former is coupled to Gq proteins, while the latter is coupled to Gi/o proteins. Accumulating evidence
Externí odkaz:
https://doaj.org/article/fcd8ec3982c746f8a704e59d36f70fea
Publikováno v:
IBRO Neuroscience Reports, Vol 13, Iss , Pp 22-30 (2022)
Major depressive disorder is a common and serious mood illness. The molecular mechanisms underlying the pathogenesis and symptomatology of depression are poorly understood at present. Multiple neurotransmitter systems are believed to be implicated in
Externí odkaz:
https://doaj.org/article/1fc574edc78547f8acac7e5afa4ed8e7
Autor:
Yun-chao Xu, Xu Liu, Min Li, Yan Li, Chun-yan Li, Ying Lu, Jaceline Sanches, Lu Wang, Yue Du, Li-min Mao, Si-bo Zuo, Hui-ting Liu, Jie Shen, Bo Wang, Li Hou, Lian-hong Li, Jian-wu Tang, Jing-fang Ju, Hong-wei Guan, Bo Song
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 378- (2022)
Externí odkaz:
https://doaj.org/article/d51db562a00147eba7a56df11b0814ed
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Group II metabotropic glutamate (mGlu) receptors (mGlu2/3) are Gαi/o-coupled receptors and are primarily located on presynaptic axonal terminals in the central nervous system. Like ionotropic glutamate receptors, group II mGlu receptors are subject
Externí odkaz:
https://doaj.org/article/dfb4b56cee0849d5b331cf3158d478a8
Autor:
Li‐Min Mao, John Q. Wang
Publikováno v:
Brain and Behavior, Vol 11, Iss 8, Pp n/a-n/a (2021)
Abstract Adenosine A1 receptors are widely expressed in the mammalian brain. Through interacting with Gαi/o‐coupled A1 receptors, the neuromodulator adenosine modulates a variety of cellular and synaptic activities. To determine the linkage from A
Externí odkaz:
https://doaj.org/article/0937414a78f94f3aa5eda59cb8980a9f
Autor:
Li‐Min Mao, John Q. Wang
Publikováno v:
Brain and Behavior, Vol 10, Iss 3, Pp n/a-n/a (2020)
Abstract Objective The adenosine A1 receptor is a Gαi/o protein‐coupled receptor and inhibits upon activation cAMP formation and protein kinase A (PKA) activity. As a widely expressed receptor in the mammalian brain, A1 receptors are implicated in
Externí odkaz:
https://doaj.org/article/15641756e3cf4844acd236767c14420c
Publikováno v:
Journal of Integrative Neuroscience, Vol 21, Iss 1, p 025 (2022)
Major depressive disorder is a chronic psychiatric disease with a high prevalence. Brain mechanisms for depression at cellular and molecular levels are far from clear. Increasing evidence from clinical and preclinical studies reveals critical roles o
Externí odkaz:
https://doaj.org/article/776ad07306b248148b2ed9795e057b0f
Autor:
Yun-chao Xu, Xu Liu, Min Li, Yan Li, Chun-yan Li, Ying Lu, Jaceline Sanches, Lu Wang, Yue Du, Li-min Mao, Si-bo Zuo, Hui-ting Liu, Jie Shen, Bo Wang, Li Hou, Lian-hong Li, Jian-wu Tang, Jing-fang Ju, Hong-wei Guan, Bo Song
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 578-590 (2018)
Doxorubicin is a widely used anthracycline-based anti-tumor agent for both solid and liquid tumors. Mounting evidence has demonstrated that microRNAs (miRNAs) are involved in chemoresistance and tumorigenesis. However, the roles of microRNA-501-5p (m
Externí odkaz:
https://doaj.org/article/8e6cedbd914c4364b80a12facf5a18c6
Publikováno v:
Journal of Molecular Neuroscience. 72:802-811
Autor:
Su Yeon Seo, Ju Hwan Yang, Sunghyun Kim, Sumin Sohn, Jeong Hwan Oh, Li‐Min Mao, John Q. Wang, Eun Sang Choe
Publikováno v:
Addiction Biology. 27
Activation of protein kinases after cocaine administration controls psychomotor behaviours by interacting with metabotropic receptors in the brain. This study identified how c-Jun N-terminal kinase (JNK) interacts with metabotropic glutamate receptor