Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Li-ling Wu"'
Autor:
Yung-Ni Lin, Jia-Rou Hsu, Chih-Lin Wang, Yi-Chen Huang, Jzy-Yu Wang, Chun-Ying Wu, Li-Ling Wu
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract This study investigates sex-specific effects in a gain-of-function model to evaluate Nfil3 function in relation to high-fat diet (HFD)-induced metabolic dysfunction-associated steatotic liver disease (MASLD) and gut microbiota (GM)-induced a
Externí odkaz:
https://doaj.org/article/4918d2bf30ed47fbac329fb9f2e9e6a2
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Circular RNAs (circRNAs) are a novel kind of non-coding RNAs proved to play crucial roles in the development of multiple diabetic complications. However, their expression and function in diabetes mellitus (DM)-impaired salivary gl
Externí odkaz:
https://doaj.org/article/3305cb233e46466286b96c301c824718
Autor:
Huey-Huey Chua, Ya-Hui Chen, Li-Ling Wu, Hung-Chih Yang, Chia-Ray Lin, Huey-Ling Chen, Jia-Feng Wu, Mei-Hwei Chang, Pei-Jer Chen, Yen-Hsuan Ni
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 361-381 (2024)
Background & Aims: A long immune-tolerant (IT) phase lasting for decades and delayed HBeAg seroconversion (HBe-SC) in patients with chronic hepatitis B (CHB) increase the risk of liver diseases. Early entry into the immune-active (IA) phase and HBe-S
Externí odkaz:
https://doaj.org/article/bb45e15e83084c77b9e1b92944f5e2a9
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102592- (2023)
Summary: There are numerous established techniques for isolating hepatic myeloid cells; however, preserving their phenotypic and functional characteristics can be challenging. We present a straightforward and efficient method to isolate hepatic myelo
Externí odkaz:
https://doaj.org/article/abde43627e0f407e826b55ee7fc4a4dd
Publikováno v:
BMC Endocrine Disorders, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Hyposalivation is one of the common symptoms of diabetes. Although long non-coding RNAs (lncRNAs) have recently been reported to play important roles in the pathogenesis of diabetes, the role of lncRNAs in diabetes-induced hyposal
Externí odkaz:
https://doaj.org/article/b4d024f8283b40a9aaa041e2fffa84ee
Autor:
Tao Shen, Wangxiao Xia, Sainan Min, Zixuan Yang, Lehua Cheng, Wei Wang, Qianxi Zhan, Fanghong Shao, Xuehan Zhang, Zhiyu Wang, Yan Zhang, Guodong Shen, Huafeng Zhang, Li-Ling Wu, Guang-Yan Yu, Qing-Peng Kong, Xiangting Wang
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-22 (2021)
Abstract Background Long noncoding RNAs (lncRNAs) are important regulators in tumor progression. However, their biological functions and underlying mechanisms in hypoxia adaptation remain largely unclear. Results Here, we established a correlation be
Externí odkaz:
https://doaj.org/article/6b5e45ada1b14e40b88891c81757e100
Autor:
Pin-Hung Lin, Chieh-Yu Liang, Bing-Yu Yao, Hui-Wen Chen, Ching-Fu Pan, Li-Ling Wu, Yi-Hsuan Lin, Yu-Sung Hsu, Yu-Han Liu, Pei-Jer Chen, Che-Ming Jack Hu, Hung-Chih Yang
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 299-314 (2021)
Antigen-specific lung-resident memory T cells (TRMs) constitute the first line of defense that mediates rapid protection against respiratory pathogens and inspires novel vaccine designs against infectious pandemic threats, yet effective means of indu
Externí odkaz:
https://doaj.org/article/c98d965d17d44110b3f83d1421c4b1b5
Autor:
Jau-Hau Horng, Wei-Hsiang Lin, Chang-Ru Wu, You-Yu Lin, Li-Ling Wu, Ding-Shinn Chen, Pei-Jer Chen
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-16 (2020)
Abstract Background Hepatitis B virus (HBV) persistently infected about 250 million people worldwide, and a curative treatment remains an unmet medical need. Among many approaches to treat chronic hepatitis B (CHB), therapeutic vaccines have been dev
Externí odkaz:
https://doaj.org/article/bc5ae5955993494189e8813b095bacfe
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0273542 (2022)
PurposeCardiac fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) proteins and leads to the maladaptive changes in myocardium. Endothelial cells (ECs) undergoing mesenchymal transition contributes to the occurrence an
Externí odkaz:
https://doaj.org/article/6e6c9a0adf144afcaa2f1631a505ab22
Autor:
Bowen Zhang, Sainan Min, Qi Guo, Yan Huang, Yuzhu Guo, Xiaolin Liang, Li-ling Wu, Guang-yan Yu, Xiangting Wang
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Increasing evidence has shown the mechanistic insights about non-coding RNA 7SK in controlling the transcription. However, the biological function and mechanism of 7SK in cancer are largely unclear. Here, we show that 7SK is down-regulated in human t
Externí odkaz:
https://doaj.org/article/1171e70953954278998b8fe05d173101