Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Li-Ying Sung"'
Autor:
Li-Kuang Tsai, Min Peng, Chia-Chun Chang, Luan Wen, Lin Liu, Xiubin Liang, Y. Eugene Chen, Jie Xu, Li-Ying Sung
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Background In eukaryotic cells, DNA double strand breaks (DSB) are primarily repaired by canonical non-homologous end joining (c-NHEJ), homologous recombination (HR) and alternative NHEJ (alt-NHEJ). Zinc finger and SCAN domain containing 4 (
Externí odkaz:
https://doaj.org/article/7dffff95d442413cad8b10bee359437b
Autor:
Chia-Jung Li, Chia-Chun Chang, Li-Kuang Tsai, Min Peng, Wei-Ni Lyu, Jane-Fang Yu, Mong-Hsun Tsai, Li-Ying Sung
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Introduction: Orangutans, classified under the Pongo genus, are an endangered non-human primate (NHP) species. Derivation of induced pluripotent stem cells (iPSCs) represents a promising avenue for conserving the genetic resources of these animals. E
Externí odkaz:
https://doaj.org/article/94d237d5cc924b6698157f5bf5458c74
Autor:
Wei‐Ju Chen, Wei‐Kai Huang, Sarshan R. Pather, Wei‐Fang Chang, Li‐Ying Sung, Han‐Chung Wu, Mei‐Ying Liao, Chi‐Chiu Lee, Hsuan‐Hui Wu, Chung‐Yi Wu, Kuo‐Shiang Liao, Chun‐Yu Lin, Shang‐Chih Yang, Hsuan Lin, Pei‐Lun Lai, Chi‐Hou Ng, Chun‐Mei Hu, I‐Chih Chen, Chi‐Hsuan Chuang, Chien‐Ying Lai, Po‐Yu Lin, Yueh‐Chang Lee, Scott C. Schuyler, Axel Schambach, Frank Leigh Lu, Jean Lu
Publikováno v:
Advanced Science, Vol 10, Iss 1, Pp n/a-n/a (2023)
Abstract Deciphering signaling mechanisms critical for the extended pluripotent stem cell (EPSC) state and primed pluripotency is necessary for understanding embryonic development. Here, a membrane protein, podocalyxin‐like protein 1 (PODXL) as bei
Externí odkaz:
https://doaj.org/article/3d6b2501eb13466ab53de0b6716d4aab
Autor:
Huan Ou-Yang, Shiao-Hsuan Yang, Wei Chen, Shang-Hsun Yang, Abdulkadir Cidem, Li-Ying Sung, Chuan-Mu Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3973 (2022)
Inverted repeat (IR) DNA sequences compose cruciform structures. Some genetic disorders are the result of genome inversion or translocation by cruciform DNA structures. The present study examined whether exogenous DNA integration into the chromosomes
Externí odkaz:
https://doaj.org/article/cdd4ceb54c6d4c6982d4a724f83e2e3a
Autor:
Gerson Dierley Keppeke, Chia Chun Chang, Min Peng, Li-Yu Chen, Wei-Cheng Lin, Li-Mei Pai, Luis Eduardo Coelho Andrade, Li-Ying Sung, Ji-Long Liu
Publikováno v:
Cell Division, Vol 13, Iss 1, Pp 1-18 (2018)
Abstract Background Inosine monophosphate dehydrogenase (IMPDH), the rate-limiting enzyme in de novo GTP biosynthesis, plays an important role in cell metabolism and proliferation. It has been demonstrated that IMPDH can aggregate into a macrostructu
Externí odkaz:
https://doaj.org/article/d728484d539048f1bbd50d3ed48c0366
Autor:
Huan Ou-Yang, Shinn-Chih Wu, Li-Ying Sung, Shiao-Hsuan Yang, Shang-Hsun Yang, Kowit-Yu Chong, Chuan-Mu Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 460 (2021)
The maternal-to-zygotic transition (MZT), which controls maternal signaling to synthesize zygotic gene products, promotes the preimplantation development of mouse zygotes to the two-cell stage. Our previous study reported that mouse granzyme g (Gzmg)
Externí odkaz:
https://doaj.org/article/0d10d2d6c15743fc90cdf31412571ace
Autor:
Wei-Fang Chang, Min Peng, Jing Hsu, Jie Xu, Huan-Chieh Cho, Hsiu-Mei Hsieh-Li, Ji-Long Liu, Chung-Hao Lu, Li-Ying Sung
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 661 (2021)
Survival motor neuron (SMN) is ubiquitously expressed in many cell types and its encoding gene, survival motor neuron 1 gene (SMN1), is highly conserved in various species. SMN is involved in the assembly of RNA spliceosomes, which are important for
Externí odkaz:
https://doaj.org/article/2f7dadb5f9994d4ca761bd4effb47164
Autor:
Wei-Fang Chang, Jie Xu, Tzu-Ying Lin, Jing Hsu, Hsiu-Mei Hsieh-Li, Yuh-Ming Hwu, Ji-Long Liu, Chung-Hao Lu, Li-Ying Sung
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 794 (2020)
The defective human survival motor neuron 1 (SMN1) gene leads to spinal muscular atrophy (SMA), the most common genetic cause of infant mortality. We previously reported that loss of SMN results in rapid differentiation of Drosophila germline stem ce
Externí odkaz:
https://doaj.org/article/c3031600605948ef9a840eb73345d652
Autor:
Wei-Cheng Lin, Archan Chakraborty, Shih-Chia Huang, Pei-Yu Wang, Ya-Ju Hsieh, Kun-Yi Chien, Yen-Hsien Lee, Chia-Chun Chang, Hsiang-Yu Tang, Yu-Tsun Lin, Chang-Shung Tung, Ji-Dung Luo, Ting-Wen Chen, Tzu-Yang Lin, Mei-Ling Cheng, Yi-Ting Chen, Chau-Ting Yeh, Ji-Long Liu, Li-Ying Sung, Ming-Shi Shiao, Jau-Song Yu, Yu-Sun Chang, Li-Mei Pai
Publikováno v:
Cell Reports, Vol 24, Iss 10, Pp 2733-2745.e7 (2018)
Summary: CTP synthase (CTPS) forms compartmentalized filaments in response to substrate availability and environmental nutrient status. However, the physiological role of filaments and mechanisms for filament assembly are not well understood. Here, w
Externí odkaz:
https://doaj.org/article/72595cfbc69e420ab2bc36c8b4f98595
Autor:
Li-Ying Sung, Wei-Fang Chang, Qian Zhang, Chia-Chia Liu, Jun-Yang Liou, Chia-Chun Chang, Huan Ou-Yang, Renpeng Guo, Haifeng Fu, Winston T.K. Cheng, Shih-Torng Ding, Chuan-Mu Chen, Maja Okuka, David L. Keefe, Y. Eugene Chen, Lin Liu, Jie Xu
Publikováno v:
Cell Reports, Vol 9, Iss 5, Pp 1603-1609 (2014)
Summary: Haplo-insufficiency of telomerase genes in humans leads to telomere syndromes such as dyskeratosis congenital and idiopathic pulmonary fibrosis. Generation of pluripotent stem cells from telomerase haplo-insufficient donor cells would provid
Externí odkaz:
https://doaj.org/article/0dda26e42d754df58a0d8c0dadffabd6