Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Li-Yin Hung"'
Autor:
Binod Kumar, Natania S. Field, Dale D. Kim, Asif A. Dar, Yanqun Chen, Aishwarya Suresh, Christopher F. Pastore, Li-Yin Hung, Nadia Porter, Keisuke Sawada, Palak Shah, Omar Elbulok, Emily K. Moser, De’Broski R. Herbert, Paula M. Oliver
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Cytokine signaling influences the differentiation of CD4+ T cells into varying functional subsets. Here the authors show that an E3 ubiquitin ligase Cul5 alters TH2 and TH9 development and absence of Cul5 in T cells results in higher levels of allerg
Externí odkaz:
https://doaj.org/article/d9e5115c68644de29848a0530e463a6f
Autor:
Babatunde Adewale, Jonathan R Heintz, Christopher F Pastore, Heather L Rossi, Li-Yin Hung, Nurudeen Rahman, Jeff Bethony, David Diemert, James Ayorinde Babatunde, De'Broski R Herbert
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009550 (2021)
Helminth infections, including hookworms and Schistosomes, can cause severe disability and death. Infection management and control would benefit from identification of biomarkers for early detection and prognosis. While animal models suggest that Tre
Externí odkaz:
https://doaj.org/article/010cffab3178446f90a71b1a43ed8bab
Autor:
Bonnie Douglas, Yun Wei, Xinshe Li, Annabel Ferguson, Li-Yin Hung, Christopher Pastore, Jonathan R Kurtz, James B McLachlan, Thomas J Nolan, James Lok, De'Broski R Herbert
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009709 (2021)
Helminths are distinct from microbial pathogens in both size and complexity, and are the likely evolutionary driving force for type 2 immunity. CD4+ helper T cells can both coordinate worm clearance and prevent immunopathology, but issues of T cell a
Externí odkaz:
https://doaj.org/article/f66ce925c97b46d69a13fbc223b51e37
Autor:
Nicole Maloney Belle, Yingbiao Ji, Karl Herbine, Yun Wei, JoonHyung Park, Kelly Zullo, Li-Yin Hung, Sriram Srivatsa, Tanner Young, Taylor Oniskey, Christopher Pastore, Wildaliz Nieves, Ma Somsouk, De’Broski R. Herbert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
TFF3 secretion by goblet cells regulates mucus viscosity and wound healing, but a receptor for TFF3 has not been identified. Here, the authors show that TFF3 binds LINGO2 to de-repress and enhance EGFR signaling that drives wound healing and immunity
Externí odkaz:
https://doaj.org/article/14dea147249543ad842b96b14c99cd1b
Autor:
Karen L Oslund, Xu Zhou, Boram Lee, Lingxiang Zhu, Trang Duong, Robert Shih, Nicole Baumgarth, Li-Yin Hung, Reen Wu, Yin Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100978 (2014)
Airway epithelial cells are the first line of defense against viral infections and are instrumental in coordinating the inflammatory response. In this study, we demonstrate the synergistic stimulation of CXCL10 mRNA and protein, a key chemokine respo
Externí odkaz:
https://doaj.org/article/0e91005d13a941159c36d5965d06f883
Publikováno v:
Clinical and Developmental Immunology, Vol 2013 (2013)
The significance of Th17 cells and interleukin- (IL-)17A signaling in host defense and disease development has been demonstrated in various infection and autoimmune models. Numerous studies have indicated that Th17 cells and its signature cytokine IL
Externí odkaz:
https://doaj.org/article/298477e320b641da961928c04643a9e5
Autor:
Kelly Zullo, Rachel Cohen, Wenjie Wei, Nicole M Maloney, Karl Herbine, Xin Wang, Zvi Cramer, Li-Yin Hung, Christopher F. Pastore, Christopher J. Lengner, De’Broski R. Herbert, Ma Somsouk, Noam A. Cohen, Bonnie Douglas, Yun Wei, Yingbiao Ji, Michael H Kohanski
Publikováno v:
Scand J Gastroenterol
Aim: Recovery of damaged mucosal surfaces following inflammatory insult requires diverse regenerative mechanisms that remain poorly defined. Previously, we demonstrated that the reparative actions of Trefoil Factor 3 (TFF3) depend upon the enigmatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d669e3936df36cee20b93c9754aa26
https://doi.org/10.1080/00365521.2021.1917650
https://doi.org/10.1080/00365521.2021.1917650
Publikováno v:
Am J Pathol
IL-33 is an IL-1 family cytokine that signals through its cognate receptor, ST2, to regulate inflammation. Whether IL-33 serves a pathogenic or protective role during inflammatory bowel disease is controversial. Herein, two different strains of cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c6a2b6f9c7397e3eca74093baffe45
https://doi.org/10.1016/j.ajpath.2020.11.004
https://doi.org/10.1016/j.ajpath.2020.11.004
Autor:
James B. Lok, Jonathan R Kurtz, Thomas J. Nolan, Yun Wei, Annabel Ferguson, Bonnie Douglas, Xinshe Li, James B. McLachlan, Li-Yin Hung, Christopher F. Pastore, De’Broski R. Herbert
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009709 (2021)
PLoS Pathogens
PLoS Pathogens
Helminths are distinct from microbial pathogens in both size and complexity, and are the likely evolutionary driving force for type 2 immunity. CD4+ helper T cells can both coordinate worm clearance and prevent immunopathology, but issues of T cell a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad2f47b519e7773470dd67582ff82a0
https://doaj.org/article/f66ce925c97b46d69a13fbc223b51e37
https://doaj.org/article/f66ce925c97b46d69a13fbc223b51e37
Autor:
Yingbiao Ji, Karl Herbine, John L. Johnson, Li-Yin Hung, David A. Christian, Christopher F. Pastore, De’Broski R. Herbert
Publikováno v:
The Journal of Immunology. 203:511-519
Whether conventional dendritic cells (cDC) acquire subset identity under direction of Wnt family glycoproteins is unknown. We demonstrate that Wnt4, a β-catenin–independent Wnt ligand, is produced by both hematopoietic and nonhematopoietic cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa94619832580c8ab3e7315c964e0ba
https://doi.org/10.4049/jimmunol.1900363
https://doi.org/10.4049/jimmunol.1900363