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Akademický článek

Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization.

Autor: Cherney EC; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Zhang L; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Lo J; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Huynh T; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Wei D; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Ahuja V; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Quesnelle C; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Schieven GL; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Futran A; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Locke GA; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Lin Z; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Monereau L; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Chaudhry C; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Blum J; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Li S; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Fereshteh M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Li-Wang B; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Gangwar S; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States., Pan C; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States., Chong C; Bristol Myers Squibb Research and Development, 700 Bay Rd, Redwood City, California 94063, United States., Zhu X; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Posy SL; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Sack JS; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Zhang P; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Ruzanov M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Harner M; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Akhtar F; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Schroeder GM; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Vite G; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States., Fink B; Bristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08543, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2022 Feb 24; Vol. 65 (4), pp. 3518-3538. Date of Electronic Publication: 2022 Feb 02.

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Vybrat výsledek číslo 2 2

Akademický článek

Correlating phase transition with heat generation through calorimetric data.

Autor: Kou Li^1,2, Li Wang³, Yu Wang⁴ y-w16@mails.tsinghua.edu.cn, Xuning Feng² fxn17@tsinghua.edu.cn, Fachao Jiang¹ jfachao@cau.edu.cn, Minggao Ouyang²

Publikováno v: eScience / Dianhuaxue. Aug2024, Vol. 4 Issue 4, p1-8. 8p.

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Vybrat výsledek číslo 3 3

Akademický článek

Novel hematopoietic progenitor kinase 1 inhibitor KHK-6 enhances T-cell activation.

Autor: Ahn, Min Jeong^1,2 (AUTHOR), Kim, Eun Hye¹ (AUTHOR), Choi, Yunha^1,3 (AUTHOR), Chae, Chong Hak¹ (AUTHOR), Kim, Pilho^1,3 (AUTHOR) hwan@krict.re.kr, Kim, Seong Hwan^1,2 (AUTHOR) hwan@krict.re.kr

Publikováno v: PLoS ONE. 6/26/2024, Vol. 19 Issue 6, p1-18. 18p.

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Vybrat výsledek číslo 4 4

Akademický článek

Critical role of kinase activity of hematopoietic progenitor kinase 1 in anti-tumor immune surveillance.

Autor: Liu J; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Curtin J; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., You D; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Hillerman S; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Li-Wang B; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Eraslan R; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Xie J; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Swanson J; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Ho CP; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Oppenheimer S; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Warrack BM; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., McNaney CA; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Nelson DM; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Blum J; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Kim T; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Fereshteh M; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Reily M; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Shipkova P; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Murtaza A; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Sanjuan M; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Hunt JT; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America., Salter-Cid L; Immuno-oncology Discovery, Bristol Myers Squibb, Princeton, New Jersey, United States of America.

Publikováno v: PloS one [PLoS One] 2019 Mar 26; Vol. 14 (3), pp. e0212670. Date of Electronic Publication: 2019 Mar 26 (Print Publication: 2019).

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Vybrat výsledek číslo 5 5

Akademický článek

Mesenchymal Stem Cells and Extracellular Vesicles: Therapeutic Potential in Organ Transplantation.

Autor: Pan, Wennuo¹ (AUTHOR), Li, Shaohan¹ (AUTHOR), Li, Kunsheng² (AUTHOR), Zhou, Pengyu³ (AUTHOR)

Publikováno v: Stem Cells International. 4/26/2024, Vol. 2024, p1-15. 15p.

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Vybrat výsledek číslo 6 6

Akademický článek

TNF‐α‐Induced KAT2A Impedes BMMSC Quiescence by Mediating Succinylation of the Mitophagy‐Related Protein VCP.

Autor: Su, Zepeng¹ (AUTHOR), Li, Jinteng¹ (AUTHOR), Lin, Jiajie¹ (AUTHOR), Li, Zhikun¹ (AUTHOR), Che, Yunshu¹ (AUTHOR), Zhang, Zhaoqiang¹ (AUTHOR), Zheng, Guan¹ (AUTHOR), Ye, Guiwen¹ (AUTHOR), Yu, Wenhui¹ (AUTHOR), Zeng, Yipeng¹ (AUTHOR), Xu, Peitao¹ (AUTHOR), Xu, Xiaojun¹ (AUTHOR), Xie, Zhongyu¹ (AUTHOR) xiezhy23@mail.sysu.edu.cn, Wu, Yanfeng² (AUTHOR) wuyf@mail.sysu.edu.cn, Shen, Huiyong¹ (AUTHOR) shenhuiy@mail.sysu.edu.cn

Publikováno v: Advanced Science. 3/13/2024, Vol. 11 Issue 10, p1-20. 20p.

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Vybrat výsledek číslo 7 7

Akademický článek

Primula weimingii (Primulaceae), a new species from Yunnan, China.