Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Li-Tian Hu"'
Autor:
Jian Chen, Biao Luo, Bi-Rou Zhong, Kun-Yi Li, Qi-Xin Wen, Li Song, Xiao-Jiao Xiang, Gui-Feng Zhou, Li-Tian Hu, Xiao-Juan Deng, Yuan-Lin Ma, Guo-Jun Chen
Publikováno v:
Genes and Diseases, Vol 8, Iss 6, Pp 867-881 (2021)
Sulfuretin is a flavonoid that protects cell from damage induced by reactive oxygen species and inflammation. In this study, we investigated the role of sulfuretin in the processing of amyloid precursor protein (APP), in association with the two cata
Externí odkaz:
https://doaj.org/article/67b39b39ae2a43ac81a57e12a858650c
Autor:
Li-Tian Hu, Xiao-Yong Xie, Gui-Feng Zhou, Qi-Xin Wen, Li Song, Biao Luo, Xiao-Juan Deng, Qiu-Ling Pan, Guo-Jun Chen
Publikováno v:
Journal of Alzheimer's disease : JAD. 91(1)
Background: Accumulation of hyperphosphorylated Tau (pTau) contributes to the formation of neurofibrillary tangles in Alzheimer’s disease (AD), and targeting Tau/pTau metabolism has emerged as a therapeutic approach. We have previously reported tha
Publikováno v:
In China Geology January 2023 6(1):171-173
Autor:
Bi-Rou Zhong, Guojun Chen, Li Song, Biao Luo, Yuanlin Ma, Li-Tian Hu, Gui-Feng Zhou, Qi-Xin Wen, Xiao-Juan Deng, Kun-Yi Li, Xiao-Jiao Xiang, Jian Chen
Publikováno v:
Journal of Neurochemistry. 157:1351-1365
Thioredoxin-2 (TXN2) is a mitochondrial protein and represents one of the intrinsic antioxidant enzymes. It has long been recognized that mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of Alzheimer's disease (AD). We hy
Autor:
Li Song, Bi-Rou Zhong, Guojun Chen, Xiao-Juan Deng, Gui-Feng Zhou, Li-Tian Hu, Yuanlin Ma, Qi-Xin Wen
Publikováno v:
The FASEB Journal. 35
Mitochondrial Tu translation elongation factor (TUFM or EF-Tu) is part of the mitochondrial translation machinery. It is reported that TUFM expression is reduced in the brain of Alzheimer's disease (AD), suggesting that TUFM might play a role in the
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundThe removal of pineal region lesions are challenging, and therapeutic strategies for their removal remain controversial. The current study was conducted to identify the characteristics and the optimal therapeutic strategies for pineal regio
Externí odkaz:
https://doaj.org/article/87afb1e7ca094452ab01b8263a8a9d1d
Autor:
Binglin Zhu, Li-Tian Hu, Xiao-Tong Hu, Jing-Si Zha, Guojun Chen, Yan Long, John H. Zhang, Yu-Jie Lai
Publikováno v:
Biochemical and biophysical research communications. 486(2)
HMGCS2 (mitochondrial 3-hydroxy-3-methylglutaryl-COA synthase 2) is a control enzyme in ketogenesis. The mitochondrial localization and interaction with APP (β-amyloid precursor protein) suggest that HMGCS2 may play a role in the pathophysiology of
Publikováno v:
Journal of Materials Processing Technology. 198:191-194
ZrO 2 –Y 2 O 3 –CuO powders were prepared by coprecipitation method. The effects of CuO content and calcining temperature on phase structure, grain size and lattice parameters were studied. The dopants CuO inhibited the increase of crystallite si
Publikováno v:
Transactions of Nonferrous Metals Society of China. 17:244-249
Oxide coatings on AM60B magnesium alloy were prepared using the microarc oxidation(MAO) technique in silicate-KOH electrolyte with addition of 0-6.0 g/L Na2WO4. The MAO processes in base electrolyte with different concentrations of Na2WO4 were studie
Publikováno v:
Genes & Diseases. 2:222-223
Multiple sclerosis (MS), a leading cause of non-traumatic disability in young adults, is a chronic inflammatory demyelinating disease of the central nervous system (CNS) associated with aberrant autoimmune responses. It has long been thought that the