Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Li-Shu Zhang"'
Autor:
Bo Tian, Jia-Heng Yao, Xu Lin, Wan-Qiang Lv, Lin-Dong Jiang, Zhuo-Qi Wang, Jie Shen, Hong-Mei Xiao, Hanli Xu, Lu-Lu Xu, Xiyu Cheng, Hui Shen, Chuan Qiu, Zhe Luo, Lan-Juan Zhao, Qiong Yan, Hong-Wen Deng, Li-Shu Zhang
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Cow milk consumption (CMC) and alterations of gut bacterial composition are proposed to be closely related to human health and disease. Our research aims to investigate the changes in human gut microbial composition in Chinese peri-/postmenopausal wo
Externí odkaz:
https://doaj.org/article/c543fe5e41cf4a579fdf024794be7974
Autor:
Li-shu Zhang, Xunlei Kang, Jianming Lu, Yuannyu Zhang, Xiaofeng Wu, Guojin Wu, Junke Zheng, Rubina Tuladhar, Heping Shi, Qiaoling Wang, Lorraine Morlock, Huiyu Yao, Lily Jun-shen Huang, Pascal Maire, James Kim, Noelle Williams, Jian Xu, Chuo Chen, Cheng Cheng Zhang, Lawrence Lum
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 145-158 (2019)
Background: Chromosomal translocation-induced expression of the chromatin modifying oncofusion protein MLL-AF9 promotes acute myelocytic leukemia (AML). Whereas WNT/β-catenin signaling has previously been shown to support MLL-AF9-driven leukemogenes
Externí odkaz:
https://doaj.org/article/73d06b7f64ea44e7a85caf179ec3fdad
Autor:
Jie-Mei Yu, Li-Shu Zhang, Yuan-Hui Fu, Feng-Min Ji, Han-Li Xu, Jia-Qiang Huang, Xiang-Lei Peng, Yan-Peng Zheng, Ying Zhang, Jin-Sheng He
Publikováno v:
Evolutionary Bioinformatics, Vol 16 (2020)
Monitoring the mutation and evolution of the virus is important for tracing its ongoing transmission and facilitating effective vaccine development. A total of 342 complete genomic sequences of SARS-CoV-2 were analyzed in this study. Compared to the
Externí odkaz:
https://doaj.org/article/c778006548e142be9a487f724c76281f
Autor:
Yong Zeng, Fei-Yan Deng, Wei Zhu, Lan Zhang, Hao He, Chao Xu, Qing Tian, Ji-Gang Zhang, Li-Shu Zhang, Hong-Gang Hu, Hong-Wen Deng
Publikováno v:
Protein & Cell, Vol 8, Iss 2, Pp 123-133 (2016)
Abstract Human monocyte is an important cell type which is involved in various complex human diseases. To better understand the biology of human monocytes and facilitate further studies, we developed the first comprehensive proteome knowledge base sp
Externí odkaz:
https://doaj.org/article/2e015b28117d43a2808187439172f9e5
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1016 (2018)
Periodontal disease is a widespread disease, which without proper treatment, may lead to tooth loss in adults. Because stem cells from the inflammatory microenvironment created by periodontal disease exhibit impaired regeneration potential even under
Externí odkaz:
https://doaj.org/article/bfa17ad369da401b8ee68a3d160a1c17
Autor:
Yan Guo, Li-Jun Tan, Shu-Feng Lei, Tie-Lin Yang, Xiang-Ding Chen, Feng Zhang, Yuan Chen, Feng Pan, Han Yan, Xiaogang Liu, Qing Tian, Zhi-Xin Zhang, Qi Zhou, Chuan Qiu, Shan-Shan Dong, Xiang-Hong Xu, Yan-Fang Guo, Xue-Zhen Zhu, Shan-Lin Liu, Xiang-Li Wang, Xi Li, Yi Luo, Li-Shu Zhang, Meng Li, Jin-Tang Wang, Ting Wen, Betty Drees, James Hamilton, Christopher J Papasian, Robert R Recker, Xiao-Ping Song, Jing Cheng, Hong-Wen Deng
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000806 (2010)
Osteoporosis is a major public health problem. It is mainly characterized by low bone mineral density (BMD) and/or low-trauma osteoporotic fractures (OF), both of which have strong genetic determination. The specific genes influencing these phenotypi
Externí odkaz:
https://doaj.org/article/e625308da1c240e195cf89b00149d2c3
Autor:
Keqiang Chen, Lin Bonan, Yingying Huang, Xiaomeng Zhou, Jiaqiang Huang, Wanghua Gong, Wu Wei, Mengdi Pang, Lin Shuye, Mingzhou Guo, Zijiang Yang, Han-Li Xu, Jianke Ren, Ji Ming Wang, Feng-Min Ji, Tian Rongmeng, Xin Guan, Wang Xiaoyue, Xiaochen Zhang, Pan Yuanming, Li-Shu Zhang
Background Hepatocellular carcinoma (HCC) is one of the most lethal human tumors with extensive heterogeneity. Serine protease 3 (PRSS3) is an indispensable member of the trypsin family and has been implicated in the pathogenesis of several malignanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8da2c8692f1efd4272b4c2d340a66d57
https://doi.org/10.21203/rs.3.rs-861068/v1
https://doi.org/10.21203/rs.3.rs-861068/v1
Autor:
Huiyu Yao, Junke Zheng, Li-shu Zhang, Lawrence G. Lum, Cheng Cheng Zhang, Lily Jun Shen Huang, Jianming Lu, Heping Shi, Noelle S. Williams, Pascal Maire, James Kim, Rubina Tuladhar, Lorraine Morlock, Chuo Chen, Xiaofeng Wu, Jian Xu, Xunlei Kang, Qiaoling Wang, Yuannyu Zhang, Guojin Wu
Publikováno v:
EBioMedicine
Background Chromosomal translocation-induced expression of the chromatin modifying oncofusion protein MLL-AF9 promotes acute myelocytic leukemia (AML). Whereas WNT/β-catenin signaling has previously been shown to support MLL-AF9-driven leukemogenesi
Autor:
Maria G. Winter, Sing Sing Way, Laura Taylor Alto, James M. Ertelt, Wesley B. Burford, Neal M. Alto, Sebastian E. Winter, Giang Pham, Li-Shu Zhang, Didi Chen
Publikováno v:
Cell Host Microbe
Summary The minimal genetic requirements for microbes to survive within multiorganism communities, including host-pathogen interactions, remain poorly understood. Here, we combined targeted gene mutagenesis with phenotype-guided genetic reassembly to
Autor:
Li-Shu Zhang, Qi Wu, Justin M. Hansen, Maarten F. de Jong, David B. Heisler, Laura Taylor Alto, Neal M. Alto
Publikováno v:
Cell Res
Cell
Cell
Gasdermin B (GSDMB) belongs to a large family of pore forming cytolysins that execute inflammatory cell death programs. While genetic studies have linked GSDMB polymorphisms to human disease, its function in the immunological response to pathogens re