Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Li-Na Cong"'
Publikováno v:
Applied Mechanics and Materials. :1294-1298
Kinematics simulation and characteristics of a new type of parallel robot manipulator (PRM) with two-dimension movement and one-dimension rotation are analyzed. The new PRM is proved to can realize expected movement, and have smooth movement curves o
Autor:
Chuan-Lin, Zhang, Li-Na, Cong, Rui, Wang, Yang, Wang, Ke-Tao, Ma, Lei, Zhao, Jun-Qiang, Si, Li, Li
Publikováno v:
Sheng li xue bao : [Acta physiologica Sinica]. 66(3)
The purposes of this study were to investigate the effect of emodin on expression of BKCa channel β1 subunit in basilar artery smooth muscle cells (BASMCs) and electrophysiological characteristics of vascular smooth muscle cells in spontaneously hyp
Publikováno v:
Molecular Endocrinology. 13:2013-2024
Caveolae may function as microdomains for signaling that help to determine specific biological actions mediated by the insulin receptor (IR). Caveolin-1, a major component of caveolae, contains a scaffolding domain (SD) that binds to a caveolin-1 bin
Autor:
Michael J. Quon, L. M. Karnitz, Robert V. Farese, Mary L. Standaert, Gautam Bandyopadhyay, Li-Na Cong, Mini P. Sajan
Publikováno v:
Molecular Endocrinology. 13:1766-1772
Previous studies have suggested that 1) atypical protein kinase C (PKC) isoforms are required for insulin stimulation of glucose transport, and 2) 3-phosphoinositide-dependent protein kinase-1 (PDK-1) is required for activation of atypical PKCs. Pres
Publikováno v:
Biochemical and Biophysical Research Communications. 255:200-207
Protein tyrosine phosphatases (PTPases) are likely to play important roles in insulin action. We recently demonstrated that the nontransmembrane PTPase PTP1B can act as a negative modulator of insulin-stimulated translocation of GLUT4. We now examine
Autor:
Li Na Cong, Yunhua Li, Zhong Yin Zhang, Michael J. Quon, Li Wu, Hui Chen, Terrence R. Burke, Zhu-Jun Yao
Publikováno v:
Biochemistry. 38:384-389
Biological actions of insulin are initiated by activation of the insulin receptor tyrosine kinase. Protein tyrosine phosphatases (PTPases) PTP1B and PTPalpha are known to dephosphorylate the insulin receptor and may contribute to insulin resistance i
Publikováno v:
Endocrinology. 139:4147-4154
α2-Heremans Schmid glycoprotein (α2-HSG) is a member of the fetuin family of serum proteins whose biological functions are not completely understood. There is a consensus thatα 2-HSG plays a role in the regulation of tissue mineralization. However
Autor:
Frederick H. Nystrom, Martha Kirby, Howard Mostowski, Lingamanaidu V. Ravichandran, Guangyuan Zeng, Michael J. Quon, Li-Na Cong
Publikováno v:
Circulation. 101(13)
Background —Previously, we demonstrated that insulin stimulates production of nitric oxide (NO) in endothelial cells. However, specific insulin-signaling pathways mediating production of NO have not been elucidated. Methods and Results —We develo
Autor:
Simeon I. Taylor, David Graham, Yunhua Li, Hui Chen, Michael J. Quon, Lixin Zhou, Li-Na Cong, Pin Xu, Salvatore Sciacchitano, Aviva R. Jacobs
Publikováno v:
Scopus-Elsevier
The insulin receptor initiates insulin action by phosphorylating multiple intracellular substrates. Previously, we have demonstrated that insulin receptor substrates (IRS)-1 and -2 can mediate insulin's action to promote translocation of GLUT4 glucos
Autor:
Michael J. Quon, Maxine A. Lesniak, Li-Na Cong, Simeon I. Taylor, Margaret A. McGibbon, Chung H. Lin, Salvatore Sciacchitano, Hui Chen, Lixin Zhou
Insulin receptor substrates-1 and -2 (IRS-1 and -2) are important substrates of the insulin receptor tyrosine kinase. Previous studies have focused upon the role of IRS-1 in mediating the actions of insulin. In the present study, we demonstrate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187ddc643f46c8a5bed3d15a7c9450e7
http://hdl.handle.net/11573/68227
http://hdl.handle.net/11573/68227