Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Li-Kwan Chang"'
Autor:
Jiun-Yan Huang, Shih-Ting Kang, I-Tung Chen, Li-Kwan Chang, Shih-Shun Lin, Guang-Hsiung Kou, Chia-Ying Chu, Chu-Fang Lo
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Members of the microRNA miR-10 family are highly conserved and play many important roles in diverse biological mechanisms, including immune-related responses and cancer-related processes in certain types of cancer. In this study, we found the most hi
Externí odkaz:
https://doaj.org/article/a46320d2e9f24e108364aae76b23802d
Autor:
Tzu-Hsuan Chang, Shie-Shan Wang, Lee-Wen Chen, Ying-Ju Shih, Li-Kwan Chang, Shih-Tung Liu, Pey-Jium Chang
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005918 (2016)
The switch between latency and the lytic cycle of Kaposi's sarcoma-associated herpesvirus (KSHV) is controlled by the expression of virally encoded ORF50 protein. Thus far, the regulatory mechanism underlying the protein stability of ORF50 is unknown
Externí odkaz:
https://doaj.org/article/8464224ed05e40ffa82f0aa04ec19a41
Publikováno v:
Molecules, Vol 15, Iss 10, Pp 7115-7124 (2010)
Reactivation of Epstein-Barr virus (EBV) from latency to the lytic cycle is required for the production of viral particles. Here, we examine the capacity of resveratrol to inhibit the EBV lytic cycle. Our results show that resveratrol inhibits the tr
Externí odkaz:
https://doaj.org/article/2d350b7755ad492aa61fda7868bc0976
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90698 (2014)
Epstein-Barr virus (EBV) expresses two transcription factors, Rta and Zta, which are involved in the transcriptional activation of EBV lytic genes. This study sought to elucidate the mechanism by which Rta activates transcription of the Zta-encoding
Externí odkaz:
https://doaj.org/article/9064a8b5157a465cb164bf87b5ba7eae
Autor:
Ya-Chun Yang, Li-Kwan Chang
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54075 (2013)
Epstein-Barr virus (EBV) expresses an immediate-early protein, Rta, to activate the transcription of EBV lytic genes. This protein usually binds to Rta-response elements or interacts with Sp1 or Zta via a mediator protein, MCAF1, to activate transcri
Externí odkaz:
https://doaj.org/article/dc15fa40d95e45c5bdfc120684d6915d
Autor:
Chia-Hao Chang, Yi-Chieh Lee, George Hsiao, Li-Kwan Chang, Wei-Chiung Chi, Yuan-Chung Cheng, Shu-Jung Huang, Tai-Chou Wang, Yi-Shan Lu, Tzong-Huei Lee
Publikováno v:
Journal of Natural Products. 85:2667-2674
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5b5e8815bea3c8dfa13927f700c699f
https://doi.org/10.1021/acs.jnatprod.2c00783
https://doi.org/10.1021/acs.jnatprod.2c00783
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15340
TRIM5α is a host anti-retroviral restriction factor that destroys human immunodeficiency virus (HIV) virions and triggers innate immune signaling. TRIM5α also mediates the autophagic degradation of target proteins via TRIMosome formation. We previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef292c56fec6cf55f8ae4592061a5a22
Autor:
Chia-Jung Wu, Chih-Yi Chen, Po-Liang Lai, Ying-Cen Chen, Wei-Hsing Tuan, Li-Kwan Chang, Hao-Yu Chang, Sseu-Pei Hwang
Publikováno v:
Ceramics International. 47:7805-7813
Synthetic bone graft has gained considerable attention because of an increase in the aged population. In the present study, a biphasic bone graft composed of hydroxyapatite (HAp) and calcium sulfate (CS) is prepared using a gel-foaming technique. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3a9772b73cfd130d99c92767742649a
https://doi.org/10.1016/j.ceramint.2020.11.126
https://doi.org/10.1016/j.ceramint.2020.11.126
Publikováno v:
Biochemical and Biophysical Research Communications. 523:773-779
Rta, a key transcription factor expressed by Epstein-Barr virus (EBV), primarily acts to induce activation of the EBV lytic cycle. Interestingly, we observed from an immunogold assay that Rta is also present on the EBV capsid in the host cell nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b401e6a7332858fda3e792fd31f364a
https://doi.org/10.1016/j.bbrc.2020.01.017
https://doi.org/10.1016/j.bbrc.2020.01.017
Autor:
Lin-Chen Huang, Sseu-Pei Hwang, Wen-Hung Wang, Min-Hsuan Lin, Chung-Wen Kuo, Hsiang-Hung Huang, Li-Kwan Chang
Publikováno v:
Journal of molecular biology. 432(19)
Rta of Epstein-Barr virus (EBV) is thought to be expressed only during the lytic cycle to promote the transcription of lytic genes. However, we found that Rta is expressed in EBV-infected B cells during viral latency, at levels detectable by immunobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3f7213af1a48002bab6a8897d0c22d
https://pubmed.ncbi.nlm.nih.gov/32710985
https://pubmed.ncbi.nlm.nih.gov/32710985