Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Li-Jyuan Luo"'
Publikováno v:
Materials Today Bio, Vol 13, Iss , Pp 100183- (2022)
The development of long lasting therapeutic agents is critically important for efficient treatment of chronic diseases. We herein report a rational strategy to develop a therapeutic thermogel featured with prolonged anti-inflammatory and corneal-prot
Externí odkaz:
https://doaj.org/article/8a180c58bd6245a2bfe0498b1d0096d6
Autor:
Dave W. Chen, Hsin-Hsin Yu, Li-Jyuan Luo, Selvaraj Rajesh Kumar, Chien-Hao Chen, Tung-Yi Lin, Jui-Yang Lai, Shingjiang Jessie Lue
Publikováno v:
Nanomaterials, Vol 9, Iss 7, p 939 (2019)
Poor osteogenesis and bacterial infections lead to an implant failure, so the enhanced osteogenic and antimicrobial activity of the implantable device is of great importance in orthopedic applications. In this study, 2-methacryloyloxyethyl phosphocho
Externí odkaz:
https://doaj.org/article/55e83d1039454399acbb384e202aa569
Publikováno v:
ACS Nano. 17:168-183
The development of therapeutics for effective treatments of retinal diseases is significantly constrained by various biological barriers. We herein report a nanomedicine strategy to develop nanotherapeutics featured with not only high retinal permeab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a76a8e9509dd8b234dc77b0d079d43d
https://doi.org/10.1021/acsnano.2c05824
https://doi.org/10.1021/acsnano.2c05824
Publikováno v:
Theranostics
Background: Y-27632 is a potent ophthalmic drug for the treatment of ocular hypertension, a globally prevalent eye disease. However, the sustained delivery of Y-27632 by a therapeutic carrier to lesion sites located in the inner segments of the eye f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9135ca7fc27ec315ce1ec23c8a22196
http://europepmc.org/articles/PMC8039939
http://europepmc.org/articles/PMC8039939
Autor:
Duc Dung Nguyen, Chun-Hsu Yao, Li-Jyuan Luo, Hung-Chi Chen, Yi-Jen Hsueh, David Hui-Kang Ma, Jui-Yang Lai
Publikováno v:
Carbohydrate polymers. 292
The functional design of scaffolding biomaterials with potent capabilities of promoting cell adhesion and proliferation is critically important for tissue repair and regeneration. Here, we exploit the effects of oxidation level of aldehyde hyaluronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6812c2b770c55352e57f3dfd83d8183d
https://pubmed.ncbi.nlm.nih.gov/35725168
https://pubmed.ncbi.nlm.nih.gov/35725168
Publikováno v:
Journal of Controlled Release. 317:246-258
Long-acting drug delivery systems with advanced functionalities are critically important to pharmacologically treat glaucomatous optic neuropathy, a chronic and multifactorial neurodegenerative disease. Here, a novel strategy based on the methoxylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec67b0784c480f2673a649a796cc598
https://doi.org/10.1016/j.jconrel.2019.11.038
https://doi.org/10.1016/j.jconrel.2019.11.038
Autor:
Jui-Yang Lai, Li-Jyuan Luo
Publikováno v:
Materials Science and Engineering: C. 98:897-909
Glaucoma is a lifelong disorder that necessitates continuous medical therapy to manage its symptoms and preserve the vision of patients; accordingly, it is highly beneficial to develop a long-acting injectable depot system that can exhibit better dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454950ed6dc87c7eef7d224ae4e4c154
https://doi.org/10.1016/j.msec.2019.01.051
https://doi.org/10.1016/j.msec.2019.01.051
Publikováno v:
Acta biomaterialia. 111
Structural designing of carriers with extended drug release profiles is critically important for achieving long-acting drug delivery systems toward efficient managements of chronic diseases. Here, we present a strategy to exploit the effects of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85d402e16a3f3255a616a1fa993b776
https://pubmed.ncbi.nlm.nih.gov/32428681
https://pubmed.ncbi.nlm.nih.gov/32428681
Publikováno v:
Chemical Engineering Journal. 429:132409
Corneal abrasion (CA) is a leading cause of inflammation, scar formation, and even loss of vision in the eye if allowed to progress; however, current treatments remain constrained by complex and sequential conditions that impede access to most therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb960c585f0cacb0f372c72ff836d72
https://doi.org/10.1016/j.cej.2021.132409
https://doi.org/10.1016/j.cej.2021.132409
Autor:
Li-Jyuan Luo, Chih-Ching Huang, Jui-Yang Lai, Binesh Unnikrishnan, Hong-Jyuan Jian, Scott G. Harroun
Publikováno v:
Applied Materials Today. 24:101156
Treatment of age-related macular degeneration (AMD) is a challenge due to frequent intravitreal injection of drugs, low retention time, risk of infection, need for drugs with multiple therapeutic efficacies, such as anti-inflammatory, anti-oxidant, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36c74587452aabd5869c89e446b2babb
https://doi.org/10.1016/j.apmt.2021.101156
https://doi.org/10.1016/j.apmt.2021.101156