Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Li-Jin Chew"'
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101592- (2020)
Summary: Signaling pathways that promote oligodendrocyte development improve oligodendrocyte regeneration and myelin recovery from demyelinating pathologies. Sox factors critically control myelin gene expression and oligodendroglial fate, but little
Externí odkaz:
https://doaj.org/article/641fa5d216e6455a814acddec63e11b9
Autor:
Li-Jin Chew, Xiaotian Ming, Brian McEllin, Jeffrey Dupree, Elim Hong, Mackenzie Catron, Melissa Fauveau, Brahim Nait-Oumesmar, Vittorio Gallo
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3173-3186.e7 (2019)
Summary: Sox17, a SoxF family member transiently upregulated during postnatal oligodendrocyte (OL) development, promotes OL cell differentiation, but its function in white matter development and pathology in vivo is unknown. Our analysis of oligodend
Externí odkaz:
https://doaj.org/article/fcde0e4105e54c69ac396d81a0dc4b93
Autor:
Beata Jablonska, Marcin Gierdalski, Li-Jin Chew, Teresa Hawley, Mackenzie Catron, Arturo Lichauco, Juan Cabrera-Luque, Tracy Yuen, David Rowitch, Vittorio Gallo
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Oligodendrocyte progenitor cell (OPC) proliferation is crucial for regeneration after hypoxic lesions in mice, a model of diffuse white matter injury of premature infants. Here, the authors show that the histone deacetylase Sirt1 is a Cdk2-dependent
Externí odkaz:
https://doaj.org/article/97db07f9d9a64b86bd58146875a5c0da
Autor:
Thomas Schmitz, Li-Jin Chew
Publikováno v:
The Scientific World Journal, Vol 8, Pp 1119-1147 (2008)
Myelin abnormalities that reflect damage to developing and mature brains are often found in neurological diseases with evidence of inflammatory infiltration and microglial activation. Many cytokines are virtually undetectable in the uninflamed centra
Externí odkaz:
https://doaj.org/article/d1979dc50f8043ba9916898abe71a634
Autor:
Joseph Abbah, Claire-Marie Vacher, Evan Z. Goldstein, Zhen Li, Srikanya Kundu, Brooke Talbot, Surajit Bhattacharya, Kazue Hashimoto-Torii, Li Wang, Payal Banerjee, Joseph Scafidi, Nathan A. Smith, Li-Jin Chew, Vittorio Gallo
Publikováno v:
The Journal of Neuroscience. 42:4812-4827
Neonatal brain injury renders the developing brain vulnerable to oxidative stress, leading to cognitive deficit. However, oxidative stress-induced damage to hippocampal circuits and the mechanisms underlying long-term changes in memory and learning a
Autor:
Vittorio Gallo, Li-Jin Chew, Jorge Edwards, Brooke M. Talbot, Jonathan Ritter, Joseph Scafidi
Newly developed targeted anticancer drugs inhibit signaling pathways commonly altered in adult and pediatric cancers. However, as these pathways are also essential for normal brain development, concerns have emerged of neurologic sequelae resulting s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4981773022ffc28d9f0c9adda13d64
https://doi.org/10.1158/0008-5472.c.6509703
https://doi.org/10.1158/0008-5472.c.6509703
Autor:
Vittorio Gallo, Li-Jin Chew, Jorge Edwards, Brooke M. Talbot, Jonathan Ritter, Joseph Scafidi
This file contains the supplemental data figures and figure legends that support the main findings in this manuscript. Supplemental file folder contains developmental expression analysis of molecular targets in the white matter and hippocampus, repre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e5c9fcde9e088fedffbd418f1704e2
https://doi.org/10.1158/0008-5472.22416990
https://doi.org/10.1158/0008-5472.22416990
Autor:
Abbah, Joseph, Vacher, Claire-Marie, Goldstein, Evan Z., Zhen Li, Kundu, Srikanya, Talbot, Brooke, Bhattacharya, Surajit, Hashimoto-Torii, Kazue, Li Wang, Banerjee, Payal, Scafidi, Joseph, Smith, Nathan A., Li-Jin Chew, Gallo, Vittorio
Publikováno v:
Journal of Neuroscience; 6/15/2022, Vol. 42 Issue 24, p4812-4827, 16p
Publikováno v:
Neurochemical Research
The cerebellum is a brain region that undergoes extremely dynamic growth during perinatal and postnatal development which is regulated by the proper interaction between glial cells and neurons with a complex concert of growth factors, chemokines, cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21f8d43dcc99ee35151bfc56fc7a92b
https://doi.org/10.1007/s11064-020-02961-z
https://doi.org/10.1007/s11064-020-02961-z
Autor:
Jonathan Ritter, Vittorio Gallo, Li-Jin Chew, Joseph Scafidi, Jorge Edwards, Brooke M. Talbot
Publikováno v:
Cancer research. 78(8)
Newly developed targeted anticancer drugs inhibit signaling pathways commonly altered in adult and pediatric cancers. However, as these pathways are also essential for normal brain development, concerns have emerged of neurologic sequelae resulting s