Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Li-Jan Chang"'
Autor:
Stephen J. Kish, Li-Jan Chang, Junchao Tong, Alan A. Wilson, Sylvain Houle, Jeffrey H. Meyer, Isabelle Boileau, Yoshiaki Furukawa
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 33:863-871
Positron emission tomography (PET) imaging of monoamine oxidases (MAO-A: [11C]harmine, [11C]clorgyline, and [11C]befloxatone; MAO-B: [11C]deprenyl-D2) has been actively pursued given clinical importance of MAOs in human neuropsychiatric disorders. Ho
Autor:
Junchao Tong, Isabelle Boileau, Sylvain Houle, Li-Jan Chang, Yoshiaki Furukawa, Alan A. Wilson, Stephen J. Kish
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 31:2065-2075
The choice of reference region in positron emission tomography (PET) human brain imaging of the vesicular monoamine transporter 2 (VMAT2), a marker of striatal dopamine innervation, has been arbitrary, with cerebellar, whole cerebral, frontal, or occ
Autor:
Junchao Tong, Isabelle Boileau, Stephen J. Kish, Allan L. Sherwin, Li-Jan Chang, Dennis J. Wickham, Gregory A. Schmunk, Lee-Cyn Ang, Paul S. Fitzmaurice, Yoshiaki Furukawa
Publikováno v:
Psychopharmacology. 202:649-661
Research on methamphetamine (MA) toxicity primarily focuses on the possibility that some of the behavioural problems in human MA users might be caused by damage to brain dopamine neurones. However, animal data also indicate that MA can damage brain s
Autor:
Nathalie Ginovart, Stephen J. Kish, Jeffrey H. Meyer, Li-Jan Chang, Alan A. Wilson, Sylvain Houle, Yoshiaki Furukawa, Junchao Tong
Publikováno v:
Nuclear Medicine and Biology. 32:123-128
Introduction The primary approach in assessing the status of brain serotonin neurons in human conditions such as major depression and exposure to the illicit drug ecstasy has been the use of neuroimaging procedures involving radiotracers that bind to
Autor:
Slobodan Dozic, Linda DiStefano, Jacques Lamarche, Yoshiaki Furukawa, Jan-Willem Taanman, Massimo Pandolfo, Mark Guttman, Frank Mastrogiacomo, Li-Jan Chang, Stephen J. Kish
Publikováno v:
Journal of Neurochemistry. 72:700-707
Controversy exists as to the clinical importance, cause, and disease specificity of the cytochrome oxidase (CO) activity reduction observed in some patients with Alzheimer's disease (AD). Although it is assumed that the enzyme is present in normal am
Autor:
Li-Jan Chang, Yves Robitaille, Stephen J. Kish, Joseph Gilbert, John H. N. Deck, M. El-Awar, Lawrence J. Schut
Publikováno v:
Annals of Neurology. 30:780-784
We measured the levels of aspartate, glutamate, gamma-aminobutyric acid (GABA), and other amino acids in autopsied brain of 6 patients from one family (Pedigree S) with dominantly inherited olivopontocerebellar atrophy. A previous demonstration of re
Publikováno v:
Journal of psychopharmacology (Oxford, England). 24(2)
Evidence that the widely used methamphetamine analog MDMA (3,4-methylenedioxymethamphetamine, ecstasy) might damage brain serotonin neurones in humans is derived from imaging investigations showing variably decreased binding of radioligands to the se
Autor:
Li-Jan Chang, Stephen J. Kish, Ali H. Rajput, Junchao Tong, Oleh Hornykiewicz, Mark Guttman, Yoshiaki Furukawa
Publikováno v:
Brain.
Interest in serotonergic involvement in Parkinson's disease (PD) has focussed recently on the possibility that the remaining serotonin neurons innervating striatum (caudate and putamen) might release dopamine as a 'false transmitter'--an action that
Autor:
Stephen J, Kish, Yoshiaki, Furukawa, Li-Jan, Chang, Junchao, Tong, Nathalie, Ginovart, Alan, Wilson, Sylvain, Houle, Jeffrey H, Meyer
Publikováno v:
Nuclear medicine and biology. 32(2)
The primary approach in assessing the status of brain serotonin neurons in human conditions such as major depression and exposure to the illicit drug ecstasy has been the use of neuroimaging procedures involving radiotracers that bind to the serotoni
Publikováno v:
Metabolic brain disease. 9(1)
We measured the levels of three glutamate metabolizing enzymes, namely, glutamate dehydrogenase (GDH), aspartate aminotransferase (AAT), and glutamine synthetase (GS) in cerebellar and occipital cortices of nine patients with dominantly-inherited oli