Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Li-Fang Hu"'
Autor:
Jin-Bao Zhang, Xiao-Jie Wan, Wen-Xiang Duan, Xue-Qin Dai, Dong Xia, Xiang Fu, Li-Fang Hu, Fen Wang, Chun-Feng Liu
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Circadian disruption often arises prior to the onset of typical motor deficits in patients with Parkinson’s disease (PD). It remains unclear whether such a prevalent non-motor manifestation would contribute to the progression of PD. Diffus
Externí odkaz:
https://doaj.org/article/0faca6adacbe480bb8b3e5e814090444
Autor:
Hsuan-Yu Chang, Chia-Chen Hsu, Li-Fang Hu, Chian-Ying Chou, Yuh-Lih Chang, Chih-Chia Lu, Li-Jen Chang
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Background Literature on the safety of remdesivir in hospitalized COVID-19 patients with severe renal impairment is limited. We aimed to investigate the safety and effectiveness of remdesivir in this population.Methods We conducted a retrospective co
Externí odkaz:
https://doaj.org/article/6fbee71a675346fead6e52707c016bb0
Autor:
Kai-Jie He, Jin-Bao Zhang, Jun-Yi Liu, Feng-Lun Zhao, Xiao-Yu Yao, Yu-Ting Tang, Jin-Ru Zhang, Xiao-Yu Cheng, Li-Fang Hu, Fen Wang, Chun-Feng Liu
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108130- (2023)
Summary: Parkinson’s disease (PD) is characterized by the irreversible loss of dopaminergic neurons and the accumulation of α-synuclein in Lewy bodies. The oligomeric α-synuclein (O-αS) is the most toxic form of α-synuclein species, and it has
Externí odkaz:
https://doaj.org/article/dff66759520d4563a10963fed7afb949
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/38c25848d3d541f7b739cebbffaeb425
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Microglia are the resident innate immune cells in the central nervous system (CNS) that serve as the first line innate immunity in response to pathogen invasion, ischemia and other pathological stimuli. Once activated, they rapidly release a variety
Externí odkaz:
https://doaj.org/article/851efaf9c83446b29f6ad1c6565dce43
Autor:
Sheng-Hong Lin, Yu-Sheng Chang, Tzu-Min Lin, Li-Fang Hu, Tsung-Yun Hou, Hui-Ching Hsu, Yu-Chuan Shen, Pei-I Kuo, Wei-Sheng Chen, Yi-Chun Lin, Jin-Hua Chen, Chi-Ching Chang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundPrevious study revealed proton pump inhibitors (PPIs) have an effect on gut microbiota. Alteration of the microbiome causes changes of the host immune system and then induces the development of autoimmune diseases (ADs). This study aimed to
Externí odkaz:
https://doaj.org/article/36bb857b229a40db92db8b90c3d7559b
Autor:
Si-Yue Li, Ya-Li Wang, Wen-Wen Liu, Dong-Jun Lyu, Fen Wang, Cheng-Jie Mao, Ya-Ping Yang, Li-Fang Hu, Chun-Feng Liu
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 9, Pp 1085-1092 (2017)
Background: Parkinson's disease (PD) patients with long-term levodopa (L-DOPA) treatment are suffering from severe circadian dysfunction. However, it is hard to distinguish that the circadian disturbance in patients is due to the disease progression
Externí odkaz:
https://doaj.org/article/da1d657d66de4984801ecb9c4441d9be
Autor:
Xiao-Lei WANG, Wei-Xing LI, Lin-Juan OU-YANG, Jie XU, Xiao-Rong CHEN, Jian-Min BIAN, Li-Fang HU, Xiao-Song PENG, Xiao-Peng HE, Jun-Ru FU, Da-Hu ZHOU, Hao-Hua HE, Xiao-Tang SUN, Chang-Lan ZHU
Publikováno v:
Acta Agronomica Sinica. 48:1141-1151
Autor:
Meng-meng Jin, Fen Wang, Di Qi, Wen-wen Liu, Chao Gu, Cheng-Jie Mao, Ya-Ping Yang, Zhong Zhao, Li-Fang Hu, Chun-Feng Liu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Neuroinflammation and autophagy dysfunction are closely related to the development of neurodegeneration such as Parkinson’s disease (PD). However, the role of autophagy in microglia polarization and neuroinflammation is poorly understood. TNF-α, w
Externí odkaz:
https://doaj.org/article/ba8d61826243403d9b88d52037a8a34c
Autor:
Yu-Chuan Shen, Hui-Ching Hsu, Tzu-Min Lin, Yu-Sheng Chang, Li-Fang Hu, Lung-Fang Chen, Sheng-Hong Lin, Pei-I. Kuo, Wei-Sheng Chen, Yi-Chun Lin, Jin-Hua Chen, Yu-Chih Liang, Chi-Ching Chang
Publikováno v:
Journal of Clinical Oncology. 40:1206-1219
PURPOSE H1-antihistamines (AHs) may exert protective effects against cancer. This study investigated the association of AH use with the risk of hepatocellular carcinoma (HCC) in patients with hepatitis B virus (HBV), hepatitis C virus (HCV), or dual