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Publikováno v:
Environmental Science and Pollution Research. 26:10835-10845
Cigarette sidestream smoke particulate matter (CSSP) is a major source of airborne metals in the indoor environment. However, the health impacts of inhalation of CSSP-bound metals are rarely studied. In this study, we quantify the amount of 37 metals
Publikováno v:
Biochimica et biophysica acta. Gene regulatory mechanisms. 1864(8)
Lung adenocarcinoma is the most common type of lung cancer in women. Our previous studies demonstrated that 17β-estradiol (E2) promoted lung adenocarcinoma cell proliferation and tumor growth through estrogen receptor ERα. Transcriptomic analysis s
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 313:L477-L490
Estrogen and secondhand smoke are key risk factors for nonsmoking female lung cancer patients who frequently have lung adenocarcinoma and show tumor estrogen receptor α (ERα) expression. We speculated that estrogen and secondhand smoke might cause
Publikováno v:
Endothelium. May2003, Vol. 10 Issue 3, p127. 13p.
Autor:
Chein Hui Hung, Pinpin Lin, Ya Hsin Cheng, Lih Ann Li, Nai Wen Chang, Li Chuan Cheng, Chingju Lin
Publikováno v:
Toxicology and Applied Pharmacology. 263:360-367
Baicalein is a flavonoid, known to have anti-inflammatory and anti-cancer effects. As an aryl hydrocarbon receptor (AhR) ligand, baicalein at high concentrations blocks AhR-mediated dioxin toxicity. Because AhR had been reported to play a role in reg
Publikováno v:
Toxicology in Vitro. 22:1832-1839
The objective was to investigate the regulation of glutathione (GSH) turnover in porcine aortic endothelial cells (PAECs) treated with sodium arsenite (NaAsO(2)), arsenic trioxide (As(2)O(3)) or sodium arsenate (Na(2)HAsO(4)) up to 72 hr at 0, 1, 5,
Publikováno v:
Crystal Growth & Design. 8:4355-4358
A new type of hybrid semiconductor co-templated by both organic cations and inorganic polyiodide anions has been synthesized and structurally characterized. The Z-scan technique indicates that it also exhibits good third-order nonlinear optical activ
Publikováno v:
Toxicology and Applied Pharmacology. 220:271-277
Epidemiological studies indicated that people exposed to dioxins were prone to the development of lung diseases including lung cancer. Animal studies demonstrated that 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) increased liver tumors and promoted lun
Publikováno v:
Biochemical pharmacology. 90(3)
Inhibition of 17α-hydroxylase/17,20-lyase (CYP17), which dictates the proceeding of androgen biosynthesis, is recommended as an effective treatment for androgen-dependent diseases. However, androgen depletion by selective CYP17 inhibition is accompa