Zobrazeno 1 - 10
of 1 989
pro vyhledávání: '"Li V"'
Autor:
Kun Wang, Sanna Iivanainen, Jussi Pekka Koivunen, Abdul Rafeh Naqash, Mahvish Muzaffar, Shravanti Macherla, James Clark, Joo Sang Lee, Eytan Ruppin, David J Pinato, Emma Mi, Daria Gramenitskaya, Sweta Jonnalagadda, Shanker Polsani, Paul R Walker, Justin D McCallen, Mona A Marie, Rahim Ali Jiwani, Maida Hafiz, Leonardo Brunetti, Chipman R G Stroud, Youngmin Chung, Li V Yang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Systemic immune activation, hallmarked by C-reactive protein (CRP) and interleukin-6 (IL-6), can modulate antitumor immune responses. In this study, we evaluated the role of IL-6 and CRP in the stratification of patients with non-small cel
Externí odkaz:
https://doaj.org/article/a4e218a69ddc41e3b8ebe5105e3ff547
Autor:
Mona A. Marie, Justin D. McCallen, Zahra S. Hamedi, Abdul Rafeh Naqash, Alexander Hoffman, Druid Atwell, Suneetha Amara, Mahvish Muzaffar, Paul R. Walker, Li V. Yang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Immunotherapy has changed the paradigm of cancer treatment, yet immune checkpoint inhibitors (ICIs) such as PD-1/PD-L1 monoclonal antibodies may cause immune-related adverse events (irAEs) in some patients. In this report, two non-small cell lung can
Externí odkaz:
https://doaj.org/article/462c3431d46d4e318e45406f316f18aa
Autor:
Abdul Rafeh Naqash, Ebenezer Appah, Li V. Yang, Mahvish Muzaffar, Mona A. Marie, Justin D. Mccallen, Shravanti Macherla, Darla Liles, Paul R. Walker
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-10 (2019)
Abstract Background Compared to conventional chemotherapy, Immune checkpoint inhibitors (ICI) are known to have a distinct toxicity profile commonly identified as immune-related adverse events (irAEs). These irAEs that are believed to be related to i
Externí odkaz:
https://doaj.org/article/8fb76ca2c40e4edd93e37771226ab1ae
Autor:
James A. McCubrey, Li V. Yang, Stephen L. Abrams, Linda S. Steelman, Matilde Y. Follo, Lucio Cocco, Stefano Ratti, Alberto M. Martelli, Giuseppa Augello, Melchiorre Cervello
Publikováno v:
Cells, Vol 11, Iss 14, p 2155 (2022)
Approximately 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC). PDAC is the fourth leading cause of cancer death world-wide. Therapies for PDAC are largely ineffective due to the dense desmoplastic tumor microenvironment which p
Externí odkaz:
https://doaj.org/article/4331f5d461c746a0aacfcd0c54461ebf
Publikováno v:
Cells, Vol 11, Iss 12, p 1900 (2022)
Pancreatic cancer (PC) is the fourth leading cause of cancer-related mortality with limited diagnostic and therapeutic options. Although immunotherapy has shown promise in the treatment of several cancers, its role in pancreatic cancer is rather limi
Externí odkaz:
https://doaj.org/article/acdbba9d04a048a2ae582a5edaec0398
Autor:
Roca, C., Bowden, N. S., Carman, L., Dazeley, S. A., Durham, S. R., Falana, O. M., Ford, M. J., Glenn, A. M., Hurlbut, C., Li, V. A., Mendenhall, M. P., Shipp, K., Sutanto, F., Zaitseva, N. P.
A $^6$Li-doped plastic scintillator with pulse-shape discrimination capabilities, commercially identified as EJ-299-50, has been developed and produced at the kilogram-scale. A total of 44 kg-scale bars of dimensions 5.5 cm $\times$ 5.5 cm $\times$ 5
Externí odkaz:
http://arxiv.org/abs/2405.19573
Autor:
Li V. Yang, Karen A. Oppelt, Mary Jane Thomassen, Mona A. Marie, Shayan Nik Akhtar, Justin D. McCallen
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first emerged in late 2019 and has since rapidly become a global pandemic. SARS-CoV-2 infection causes damages to the lung and other organs. Th
Externí odkaz:
https://doaj.org/article/9ecb2fddef54487ab21e5c6e347bb894
Autor:
Elizabeth A. Krewson, Edward J. Sanderlin, Mona A. Marie, Shayan Nik Akhtar, Juraj Velcicky, Pius Loetscher, Li V. Yang
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: GPR4 is a pH-sensing G protein-coupled receptor highly expressed in vascular endothelial cells and can be activated by protons in the inflamed tissue microenvironment. Herein, we report that acidosis-induced GPR4 activation increases paracel
Externí odkaz:
https://doaj.org/article/86bc5ccceee44f9aa6e7d489577ae5e2
Autor:
Calvin R. Justus, Edward J. Sanderlin, Lixue Dong, Tianai Sun, Jen-Tsan Chi, Kvin Lertpiriyapong, Li V. Yang
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-14 (2017)
Abstract Background Extracellular acidosis is a condition found within the tumor microenvironment due to inadequate blood perfusion, hypoxia, and altered tumor cell metabolism. Acidosis has pleiotropic effects on malignant progression; therefore it i
Externí odkaz:
https://doaj.org/article/3afe9c26f7bc49668b4dd7a72f3b3cd1
Autor:
Yuhua Wen, Zhan Chen, Jianfen Lu, Elizabeth Ables, Jean-Luc Scemama, Li V Yang, Jun Q Lu, Xin-Hua Hu
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184726 (2017)
Morphological changes in apoptotic cells provide essential markers for defining and detection of apoptosis as a fundamental mechanism of cell death. Among these changes, the nuclear fragmentation and condensation have been regarded as the important m
Externí odkaz:
https://doaj.org/article/6c5da403eb944ae098d963a4527da920