Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Li Theng Ng"'
Autor:
Li Theng Ng, Li Fang Ng, Richard Ming Yi Tang, Diogo Barardo, Barry Halliwell, Philip Keith Moore, Jan Gruber
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 6, Iss 1, Pp 1-14 (2020)
Abstract Caloric restriction (CR) is one of the most effective interventions to prolong lifespan and promote health. Recently, it has been suggested that hydrogen sulfide (H2S) may play a pivotal role in mediating some of these CR-associated benefits
Externí odkaz:
https://doaj.org/article/b0d8bd33beb746bda80e4ac101a4e47c
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
The mitochondrial free radical theory of aging (mFRTA) proposes that accumulation of oxidative damage to macromolecules in mitochondria is a causative mechanism for aging. Accumulation of mitochondrial DNA (mtDNA) damage may be of particular interest
Externí odkaz:
https://doaj.org/article/4b8b53e841e74e639d62862ce938cab1
Autor:
Shin Yee Hong, Li Theng Ng, Li Fang Ng, Takao Inoue, Nicholas S Tolwinski, Thilo Hagen, Jan Gruber
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168752 (2016)
In recent years, various large-scale proteomic studies have demonstrated that mitochondrial proteins are highly acylated, most commonly by addition of acetyl and succinyl groups. These acyl modifications may be enzyme catalysed but can also be driven
Externí odkaz:
https://doaj.org/article/f85bebc6cd214ab49805c0e7f62762f5
Autor:
Barry Halliwell, Li Fang Ng, Jan Gruber, Li Theng Ng, Richard Ming Yi Tang, Philip K. Moore, Diogo Barardo
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 6, Iss 1, Pp 1-14 (2020)
Caloric restriction (CR) is one of the most effective interventions to prolong lifespan and promote health. Recently, it has been suggested that hydrogen sulfide (H2S) may play a pivotal role in mediating some of these CR-associated benefits. While t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b71950a57a3aaa46fe6fac7cba8650
https://doaj.org/article/b0d8bd33beb746bda80e4ac101a4e47c
https://doaj.org/article/b0d8bd33beb746bda80e4ac101a4e47c
Publikováno v:
Biochemical Pharmacology. 149:91-100
Caloric restriction (CR) is a dietary regimen that aims to reduce the intake of total calories while maintaining adequate supply of key nutrients so as to avoid malnutrition. CR is one of only a small number of interventions that show promising outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5d836354e4cb6d3d6484dfc8411be95
https://doi.org/10.1016/j.bcp.2018.01.030
https://doi.org/10.1016/j.bcp.2018.01.030
Inhibition of amyloid-induced toxicity by ergothioneine in a transgenic Caenorhabditis elegans model
Autor:
Vanessa Yuk Man Lam, Jan Gruber, Barry Halliwell, Keith Hsiu Chin Lim, Li Fang Ng, Li-Theng Ng, Cheryl Y.W. Huang, Irwin K. Cheah, Fang‐Qin Goh
Publikováno v:
FEBS lettersReferences. 593(16)
The abnormal accumulation of β-amyloid peptide (Aβ) is recognized as a central component in the pathogenesis of Alzheimer disease. While many aspects of Aβ-mediated neurotoxicity remain elusive, Aβ has been associated with numerous underlying pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d848ffe54bef629d49736f0b10d07f9
https://pubmed.ncbi.nlm.nih.gov/31211853
https://pubmed.ncbi.nlm.nih.gov/31211853
Autor:
Li Theng, Ng, Li Fang, Ng, Richard Ming Yi, Tang, Diogo, Barardo, Barry, Halliwell, Philip Keith, Moore, Jan, Gruber
Publikováno v:
NPJ Aging and Mechanisms of Disease
Caloric restriction (CR) is one of the most effective interventions to prolong lifespan and promote health. Recently, it has been suggested that hydrogen sulfide (H2S) may play a pivotal role in mediating some of these CR-associated benefits. While t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::733b286b7fc35a5ab005508586732d3a
https://pubmed.ncbi.nlm.nih.gov/32566245
https://pubmed.ncbi.nlm.nih.gov/32566245
Publikováno v:
Frontiers in Genetics
The mitochondrial free radical theory of aging (mFRTA) proposes that accumulation of oxidative damage to macromolecules in mitochondria is a causative mechanism for aging. Accumulation of mitochondrial DNA (mtDNA) damage may be of particular interest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71bbd068ac34eb153495061ccacd722b
https://pubmed.ncbi.nlm.nih.gov/31031801
https://pubmed.ncbi.nlm.nih.gov/31031801
Publikováno v:
Biogerontology. 18(2)
Hypometabolism may play an important role in the pathogenesis of ageing and ageing-related diseases. The nematode Caenorhabditis elegans offers the opportunity to study “living mitochondria” in a small (~1 mm) animal replete with a highly stereot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6b17e0c6e629d621d9580f5ab11afcc
https://pubmed.ncbi.nlm.nih.gov/28039571
https://pubmed.ncbi.nlm.nih.gov/28039571
Autor:
Andrew A. Bettiol, Yuanjun Yan, Jan Gruber, Daryl Boey, Nitish V. Thakor, Chia-Hung Chen, Li Theng Ng
Publikováno v:
Biosensorsbioelectronics. 77
The nematode Caenorhabditis elegans has become an essential model organism in neuroscience research because of its stereotyped anatomy, relevance to human biology, and capacity for genetic manipulation. To solve the intrinsic challenges associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6ea64fa1a6d6a7a6a7030092d35515
https://pubmed.ncbi.nlm.nih.gov/26452079
https://pubmed.ncbi.nlm.nih.gov/26452079