Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Li Na Zhao"'
Autor:
Philipp Kaldis, Li Na Zhao
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0293243 (2024)
PIWI-interacting RNAs (piRNAs) are important for ensuring the integrity of the germline. 3'-terminal 2'-O-methylation is essential for piRNA maturation and to protect them from degradation. HENMT1 (HEN Methyltransferase 1) carries out the 2'-O-methyl
Externí odkaz:
https://doaj.org/article/168636796de14f5f92ff15807e050a22
Autor:
Li Na Zhao, Philipp Kaldis
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 5, p e1010140 (2022)
Methylenetetrahydrofolate dehydrogenase/cyclohydrolase (MTHFD2) is a new drug target that is expressed in cancer cells but not in normal adult cells, which provides an Achilles heel to selectively kill cancer cells. Despite the availability of crysta
Externí odkaz:
https://doaj.org/article/ab32a02e33554caab90db292e1ddb641
Publikováno v:
Journal of International Medical Research, Vol 47 (2019)
The heart is one of the organs most vulnerable to sepsis. This review describes the general characteristics of sepsis-induced cardiomyopathy and the main pathogenesis of myocardial dysfunction in sepsis. Levosimendan is a novel drug for treatment of
Externí odkaz:
https://doaj.org/article/bb45093e1e044b73b0adc55ee95688ac
Autor:
Kishore Reddy Venkata Thappeta, Li Na Zhao, Choy Eng Nge, Sharon Crasta, Chung Yan Leong, Veronica Ng, Yoganathan Kanagasundaram, Hao Fan, Siew Bee Ng
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8601 (2020)
Sortase A (SrtA) is a membrane-associated enzyme that anchors surface-exposed proteins to the cell wall envelope of Gram-positive bacteria such as Staphylococcus aureus. As SrtA is essential for Gram-positive bacterial pathogenesis but dispensable fo
Externí odkaz:
https://doaj.org/article/9de240cf4bf74ca78a07f313ac2f55d2
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 7, Pp 12631-12650 (2014)
The single-mutation of genes associated with Alzheimer’s disease (AD) increases the production of Aβ peptides. An elevated concentration of Aβ peptides is prone to aggregation into oligomers and further deposition as plaque. Aβ plaques and neuro
Externí odkaz:
https://doaj.org/article/eed03caf2e86431dae2d7197c2e4fdec
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 6, Pp 7303-7327 (2012)
Abstract: In this review, we elucidate the mechanisms of Aβ oligomer toxicity which may contribute to Alzheimer’s disease (AD). In particular, we discuss on the interaction of Aβ oligomers with the membrane through the process of adsorption and i
Externí odkaz:
https://doaj.org/article/64fa9ff1040c4afcaad2b968b4600fdf
Publikováno v:
Journal of Mountain Science. 19:3118-3130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fd647c5b925547a483225bacb8e605b
https://doi.org/10.1007/s11629-022-7458-7
https://doi.org/10.1007/s11629-022-7458-7
Publikováno v:
Journal of Colloid and Interface Science. 622:357-366
In order to achieve in-situ H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4cd574320474b5751d2de47ff781b6
https://doi.org/10.1016/j.jcis.2022.04.108
https://doi.org/10.1016/j.jcis.2022.04.108
Autor:
Yu-Chun Song, Xue-Na Yan, Yu Tang, Hao Jing, Na Zhang, Jun Zhang, Ya-Hua Zhong, Li-Hua Dong, Hong-Fen Wu, Jian Tie, Qiu-Zi Zhong, Wei-Fang Yang, Xiao-Hong Wang, Xiao-Rong Hou, Yu-Fei Lu, Li-Na Zhao, Jing Jin, Ye-Xiong Li, Shu-Lian Wang
Publikováno v:
Practical Radiation Oncology. 12:397-408
To estimate the variations in clinical target volumes (CTVs) and organs at risk delineation within the quality assurance (QA) program of the POTENTIAL trial, which is a multicenter, randomized phase 3 trial evaluating postmastectomy radiation therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8a83935fbbbb88921a190ca306cdbc
https://doi.org/10.1016/j.prro.2021.12.018
https://doi.org/10.1016/j.prro.2021.12.018
Publikováno v:
MycoKeys 92: 79-93
In this study, Pseudosperma arenarium is proposed as a new species, based on morphological, ecological, molecular and biochemical evidence. The new species grows on sandy ground under Populus and Pinus sylvestris in north-western China and northern E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0249535d4e6cb8ba5ae83cd212464a5b
https://doi.org/10.3897/mycokeys.92.86277
https://doi.org/10.3897/mycokeys.92.86277