Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Li Jung Tai"'
Autor:
Nicholas J. Viney, Shuling Guo, Li‐Jung Tai, Brenda F. Baker, Mariam Aghajan, Shiangtung W. Jung, Rosie Z. Yu, Sheri Booten, Heather Murray, Todd Machemer, Sebastien Burel, Sue Murray, Gustavo Buchele, Sotirios Tsimikas, Eugene Schneider, Richard S. Geary, Merrill D. Benson, Brett P. Monia
Publikováno v:
ESC Heart Failure, Vol 8, Iss 1, Pp 652-661 (2021)
Abstract Aims Amyloidogenic transthyretin (ATTR) amyloidosis is a fatal disease characterized by progressive cardiomyopathy and/or polyneuropathy. AKCEA‐TTR‐LRx (ION‐682884) is a ligand‐conjugated antisense drug designed for receptor‐mediat
Externí odkaz:
https://doaj.org/article/3297462a8e6e4c1081fbb6040b37c72e
Autor:
Nicholas Johnson, John Day, Johanna Hamel, Charles Thornton, S Subramony, Payam Soltanzadeh, Jeffrey Statland, William Arnold, Matthew Wicklund, Kelly Ditrapani, Carrie Heusner, Chao-Yin Chen, Bradley McEvoy, Yiming Zhu, Li-Jung Tai, Elizabeth Ackermann
Publikováno v:
Thursday, April 27.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8916fd2cb0933c368b50cb0371a030e8
https://doi.org/10.1212/wnl.0000000000202529
https://doi.org/10.1212/wnl.0000000000202529
Publikováno v:
Review of Scientific Instruments. 94:035109
This paper presents novel surface profilometry for both geometric part error and metallurgical material property distribution measurements of the additively manufactured and post-processed rods. The measurement system, the so-called fiber optic-eddy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::143a7e382bc7776ad6f24f974782f6f5
https://doi.org/10.1063/5.0135514
https://doi.org/10.1063/5.0135514
Autor:
Shiangtung W. Jung, Li Jung Tai, Márcia Waddington-Cruz, William J. Litchy, Sotirios Tsimikas, Peter J. Dyck, Cecilia Monteiro, Gustavo Buchele, Julian D. Gillmore, Michela Brambatti, John L. Berk, Eugene Schneider, Yukio Ando, Teresa Coelho, Morie A. Gertz, Merrill D. Benson, Nicholas J. Viney, Louis O'Dea, Richard S. Geary, Brett P. Monia, Sami Khella, Laura Obici
Publikováno v:
Neurology and therapy, vol 10, iss 1
Neurology and Therapy
Neurology and Therapy
Introduction AKCEA-TTR-LRx is a ligand-conjugated antisense (LICA) drug in development for the treatment of hereditary transthyretin amyloidosis (hATTR), a fatal disease caused by mutations in the transthyretin (TTR) gene. AKCEA-TTR-LRx shares the sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae92472f0364a8018070ff0215ebd0d
https://doi.org/10.1007/s40120-021-00235-6
https://doi.org/10.1007/s40120-021-00235-6
Publikováno v:
Review of Scientific Instruments; Mar2023, Vol. 34 Issue 3, p1-8, 8p
Autor:
Eugene Schneider, Li-Jung Tai, Sebastien A. Burel, Padmakumar Narayanan, Joseph A. Tami, Lijiang Shen, Joseph L. Witztum, T. Jesse Kwoh, Scott P. Henry, Suzanne Paz, Brett P. Monia, Steven G. Hughes, Jeffery A Engelhardt, Sanford J. Shattil, Shuting Xia, Todd Machemer, Brian R. Curtis
Publikováno v:
Nucleic Acid Therapeutics. 30:94-103
Inotersen, a 2'-O-methoxyethyl (2'-MOE) phosphorothioate antisense oligonucleotide, reduced disease progression and improved quality of life in patients with hereditary transthyretin amyloidosis with polyneuropathy (hATTR-PN) in the NEURO-TTR and NEU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3ffffb1daa283b051e7ec72a1e47a2
https://doi.org/10.1089/nat.2019.0829
https://doi.org/10.1089/nat.2019.0829
Autor:
Martin Gajdošík, Julia K. Overman, Erin S. Morgan, Richard S. Geary, Li-Jung Tai, Shiangtung W. Jung, Lynnetta Watts, Brenda F. Baker, Martin Krššák, Michael Krebs, Sanjay Bhanot, Anne Smith, Nguyen C. Pham
Publikováno v:
Diabetes Care. 42:585-593
OBJECTIVE To evaluate the safety and efficacy of IONIS-GCGRRx, a 2′-O-methoxyethyl antisense oligonucleotide targeting the glucagon receptor (GCGR), and the underlying mechanism of liver transaminase increases in patients with type 2 diabetes on st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53ebb99ae677c4e5967eefb37b6fa2fe
https://doi.org/10.2337/dc18-1343
https://doi.org/10.2337/dc18-1343
Autor:
Sheri L. Booten, Gustavo Buchele, Mariam Aghajan, Todd Machemer, Brett P. Monia, Richard S. Geary, Nicholas J. Viney, Sue Murray, Merrill D. Benson, Sebastien A. Burel, Sotirios Tsimikas, Shuling Guo, Eugene Schneider, Shiangtung W. Jung, Brenda F. Baker, Heather M. Murray, Li-Jung Tai, Rosie Z. Yu
Publikováno v:
ESC heart failure, vol 8, iss 1
ESC Heart Failure, Vol 8, Iss 1, Pp 652-661 (2021)
ESC Heart Failure
ESC Heart Failure, Vol 8, Iss 1, Pp 652-661 (2021)
ESC Heart Failure
AimsAmyloidogenic transthyretin (ATTR) amyloidosis is a fatal disease characterized by progressive cardiomyopathy and/or polyneuropathy. AKCEA-TTR-LRx (ION-682884) is a ligand-conjugated antisense drug designed for receptor-mediated uptake by hepatoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff308bcce12264c19717432639a3fe9f
https://escholarship.org/uc/item/41n576q7
https://escholarship.org/uc/item/41n576q7
Autor:
Erin S, Morgan, Li-Jung, Tai, Nguyen C, Pham, Julia K, Overman, Lynnetta M, Watts, Anne, Smith, Shiangtung W, Jung, Martin, Gajdošík, Martin, Krššák, Michael, Krebs, Richard S, Geary, Brenda F, Baker, Sanjay, Bhanot
Publikováno v:
Diabetes care. 42(4)
To evaluate the safety and efficacy of IONIS-GCGRIn three phase 2, randomized, double-blind studies, patients with type 2 diabetes on metformin received weekly subcutaneous injections of IONIS-GCGRSignificant reductions in HbAIONIS-GCGR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cdfee04115b485f4ba28d2de7675a073
https://pubmed.ncbi.nlm.nih.gov/30765435
https://pubmed.ncbi.nlm.nih.gov/30765435