Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Li Jian Yap"'
Autor:
Li Jian Yap, Dahai Luo, Ka Yan Chung, Siew Pheng Lim, Christophe Bodenreider, Christian Noble, Pei-Yong Shi, Julien Lescar
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12836 (2010)
The N-terminal domain of the flavivirus NS5 protein functions as a methyltransferase (MTase). It sequentially methylates the N7 and 2'-O positions of the viral RNA cap structure (GpppA→(7me)GpppA→(7me)GpppA(2'-O-me)). The same NS5 domain could al
Externí odkaz:
https://doaj.org/article/b42b0853a571424f90c622a09a1b7d53
Autor:
Chin Chin Lim, Yin Hoe Yau, Gang Zou, Pei Yong Shi, Yen Liang Chen, Hongping Dong, Susana Geifman Shochat, Julien Lescar, Li Jian Yap
Publikováno v:
Journal of Biological Chemistry
Flavivirus NS5 protein encodes methyltransferase and RNA-dependent RNA polymerase (RdRp) activities. Structural analysis of flavivirus RdRp domains uncovered two conserved cavities (A and B). Both cavities are located in the thumb subdomains and repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf56704f07bc28aba586c03f225953e0
Autor:
Julien Lescar, Christian G. Noble, Li Jian Yap, Christophe Bodenreider, Siew Pheng Lim, Ka Yan Chung, Pei Yong Shi, Dahai Luo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9 (2010)
PLoS ONE, Vol 5, Iss 9 (2010)
The N-terminal domain of the flavivirus NS5 protein functions as a methyltransferase (MTase). It sequentially methylates the N7 and 2'-O positions of the viral RNA cap structure (GpppA→(7me)GpppA→(7me)GpppA(2'-O-me)). The same NS5 domain could al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8fc4e466ab870736880ae673c525a6
http://europepmc.org/articles/PMC2941465
http://europepmc.org/articles/PMC2941465
Autor:
Gang Zou1, Yen-Liang Chen1, Hongping Dong1, Chin Chin Lim1, Li Jian Yap2, Yin Hoe Yau2, Shochat, Susana Geifman2, Lescar, Julien2, Pei-Yong Shi1 peiyong.shi@novartis.com
Publikováno v:
Journal of Biological Chemistry. 4/22/2011, Vol. 286 Issue 16, p14362-14372. 11p.