Toxicity Study of 28-Day Subcutaneous Injection of Arctigenin in Beagle Dogs

Autor: Jie Li, Yun-gang Lv, Li-hong Pan, Fang-fang Yao, Tao Peng, Yu-jun Tan, Gui-Min Zhang, Zhong Liu, Jing-chun Yao, Yu-shan Ren

Publikováno v: Frontiers in Pharmacology, Vol 10 (2019)

Our previous studies have investigated the systematic pharmacokinetic characteristics, biological activities, and toxicity of arctigenin. In this research, the potential toxicities of arctigenin in beagle dogs were investigated via repeated 28-day su

Externí odkaz: https://doaj.org/article/d790a16df1514f96b1e35ccee469615c

Downregulation of leptin inhibits growth and induces apoptosis of lung cancer cells via the Notch and JAK/STAT3 signaling pathways

Autor: Xian-Jie Zheng, Zhong-Xin Yang, Yan-Jun Dong, Guo-Yu Zhang, Ming-Fei Sun, Xiao-Kang An, Li-Hong Pan, Shuang-Lin Zhang

Publikováno v: Biology Open, Vol 5, Iss 6, Pp 794-800 (2016)

Previous studies have documented that leptin is involved in the pathogenesis of many human cancer types by regulation of numerous signal transduction pathways. The aim of this study was to investigate the biological roles of leptin and the mechanisms

Externí odkaz: https://doaj.org/article/95e8e927216b427489b454004b025663

[Proteomic study of Jingfang Mixture on urticaria based on label-free quantitative proteomics technology]

Autor: Yu, Cheng, Li-Hong, Pan, Shi-Rong, Li, Li, Zhang, De-Jun, Niu, Cheng-Hong, Sun, Yong-Xia, Guan

Publikováno v: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 47(20)

This study aims to explore the effect of Jingfang Mixture on the protein expression of urticaria in mice and explain the mechanism of Jingfang Mixture in the treatment of urticaria. Twenty-seven male Kunming mice were randomly divided into a normal g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8b9c4a9148c7a8b70c766d631bcefe43
https://pubmed.ncbi.nlm.nih.gov/36471965

Environmental eustress improves postinfarction cardiac repair via enhancing cardiac macrophage survival

Autor: Pei-Yuan Bai, Si-Qin Chen, Dai-Le Jia, Li-Hong Pan, Chao-Bao Liu, Jin Liu, Wei Luo, Yang Yang, Ma-Yu Sun, Nai-Fu Wan, Wu-Wei Rong, Ai-Jun Sun, Jun-Bo Ge

Publikováno v: Science Advances. 8

Macrophages play a vital role in cardiac repair following myocardial infarction (MI). An enriched environment (EE) is involved in the regulation of macrophage-related activities and disease progression; however, whether EE affects the phenotype and f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0e47594c83e0f0667d402e6ba46d8c
https://doi.org/10.1126/sciadv.abm3436

Essential oil from Euphorbia esula inhibits proliferation and induces apoptosis in HepG2 cells via mitochondrial dysfunction

Autor: Qiang Wang, Li-Hong Pan, Xinzhou Yang, Jie Yang, Xinhua Ma, Yanzhang Wen, Hao Chen, Mi Huang, Dan Lv, Ren Zhang

Publikováno v: Brazilian Journal of Pharmaceutical Sciences; Vol. 56 (2020); e17542
Brazilian Journal of Pharmaceutical Sciences; v. 56 (2020); e17542
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 56 (2020)
Brazilian Journal of Pharmaceutical Sciences, Volume: 56, Article number: e17542, Published: 16 MAR 2020

Hepatocellular carcinoma is one of the most prevalent malignancies and a leading cause of cancer-related mortality worldwide. However, the therapies to prevent hepatocellular carcinoma are still limited and the emergence of drug resistance leads to t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9eda345725bfee01db4186f8faa6e5
https://www.revistas.usp.br/bjps/article/view/181352