Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Li F Chan"'
Autor:
Rachel Forfar, Mashal Hussain, Puneet Khurana, Jennifer Cook, Steve Lewis, Dillon Popat, David Jackson, Ed McIver, Jeff Jerman, Debra Taylor, Adrian JL Clark, Li F Chan
Publikováno v:
Endocrine Connections, Vol 11, Iss 12, Pp 1-8 (2022)
The overproduction of adrenocorticotropic hormone (ACTH), in conditions such as Cushing’s disease and congenital adrenal hyperplasia (CAH), leads to significant morbidity. Current treatment with glucocorticoids does not adequately suppress plasma A
Externí odkaz:
https://doaj.org/article/a3421e3c0a9b4225a1499774c9548e05
Autor:
Ashwini Maudhoo, Avinaash Maharaj, Federica Buonocore, Gabriel Angel Martos-Moreno, Jesús Argente, John C Achermann, Li F Chan, Lou A Metherell
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2021)
Congenital isolated ACTH deficiency (IAD) is a rare condition characterised by low plasma ACTH and serum cortisol with normal production of other pituitary hormones. TBX19 (also known as TPIT) is a T-box pituitary restricted transcription factor impo
Externí odkaz:
https://doaj.org/article/0e7589f553444aaabd52e695b904977c
Autor:
Tatiana V Novoselova, Peter J King, Leonardo Guasti, Louise A Metherell, Adrian J L Clark, Li F Chan
Publikováno v:
Endocrine Connections, Vol 8, Iss 7, Pp R122-R130 (2019)
The melanocortin-2-receptor (MC2R), also known as the ACTH receptor, is a critical component of the hypothalamic–pituitary–adrenal axis. The importance of MC2R in adrenal physiology is exemplified by the condition familial glucocorticoid deficien
Externí odkaz:
https://doaj.org/article/fbbcdc59c9ea49b5af7007e908e78ad9
Publikováno v:
Frontiers in Endocrinology, Vol 6 (2015)
Adrenal insufficiency is a rare, but potentially fatal medical condition. In children the cause is most commonly congenital and in recent years a growing number of causative gene mutations have been identified resulting in a myriad of syndromes that
Externí odkaz:
https://doaj.org/article/e1805122ba55462a978d2f17845300a2
Publikováno v:
The Lancet Public Health. 8:e453-e462
Autor:
Saptarshi Maitra, Christopher Smith, Charlotte Hall, Jordan Read, Avinaash V Maharaj, Marroquin Ramirez Lucia Mariela, Younus Qamar, Rathi Prasad, Li F Chan, Louise A Metherell
Publikováno v:
Endocrine Abstracts.
Autor:
Yoav Peleg, Amandeep Kaur Gill, Peter J. McCormick, Masha Y. Niv, Vidicha Chunilal, Joaquin Botta, Nicolas J. Roth, Vadivel Prabahar, Hadar Israeli, Li F. Chan, Moran Shalev-Benami, Oksana Degtjarik, Fabrizio Fierro, Danny Ben-Zvi
Publikováno v:
Science. 372:808-814
To eat or not to eat Melanocortin receptor 4 (MC4R) plays a role in regulating food intake: Its activation by a stimulating hormone inhibits appetite, whereas binding to a natural antagonist promotes appetite. Complementing a recent structure of MC4R
Autor:
Cristina Perez-Ternero, Aisah A. Aubdool, Raj Makwana, Gareth J. Sanger, Roland H. Stimson, Li F. Chan, Amie J. Moyes, Adrian J. Hobbs
Publikováno v:
Perez-Ternero, C, Aubdool, A A, Makwana, R, Sanger, G J, Stimson, R H, Chan, L F, Moyes, A J & Hobbs, A J 2022, ' C-type natriuretic peptide is a pivotal regulator of metabolic homeostasis ', Proceedings of the National Academy of Sciences . https://doi.org/10.1073/pnas.2116470119
Thermogenesis and adipogenesis are tightly regulated mechanisms that maintain lipid homeostasis and energy balance; dysfunction of these critical processes underpins obesity and contributes to cardiometabolic disease. C-type natriuretic peptide (CNP)
Autor:
R. Asaad Baksh, Sarah E. Pape, Li F. Chan, Aisha A. Aslam, Martin C. Gulliford, Andre Strydom
Publikováno v:
SSRN Electronic Journal.
BackgroundAdrenal suppression is a clinically concerning side effect of inhaled corticosteroid (ICS) treatment in patients with asthma. Increased susceptibility to ICS-induced adrenal suppression has previously been identified in those with the rs591
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96b0e5ae8daeb47f0200232701e99c50
https://doi.org/10.21203/rs.3.rs-1152078/v1
https://doi.org/10.21203/rs.3.rs-1152078/v1