Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Li Bo Zou"'
Publikováno v:
Acta Pharmacologica Sinica. 43:1916-1927
PTEN-induced putative kinase 1 (PINK1)/parkin pathway mediates mitophagy, which is a specialized form of autophagy. Evidence shows that PINK1 can exert protective effects against stress-induced neuronal cell death. In the present study we investigate
Publikováno v:
Journal of Pharmacological Sciences, Vol 122, Iss 4, Pp 305-317 (2013)
An accumulating body of evidence suggests that Alzheimer’s disease (AD) is associated with microglia-mediated neuroinflammation and pro-inflammatory cytokine expression. Therefore, the suppression of neuroinflammation and pro-inflammatory cytokine
Externí odkaz:
https://doaj.org/article/856045c159304ae2abfaf999c10e59eb
Autor:
Wen-Hao Fan, Zong-Gui Yu, Hui Zhang, Yong-Nan Xu, Li-Bo Zou, Yi-Xia Gong, Hui-Ming Hua, Jian-Yu Liu, Ying-Li Guan
Publikováno v:
Molecules, Vol 17, Iss 5, Pp 5520-5531 (2012)
Four new oleanene-type triterpenoid saponins together with six known saponins were isolated from the roots of Pulsatilla cernua and their structures were elucidated on the basis of spectroscopic data, including 2D NMR spectra and chemical evidence. A
Externí odkaz:
https://doaj.org/article/958a61d60eff4060931a890bc2fce4b7
Autor:
Yue, Qi, Xue-Fei, Ji, Tian-Yan, Chi, Peng, Liu, Ge, Jin, Qian, Xu, Qing, Jiao, Li-Hua, Wang, Li-Bo, Zou
Publikováno v:
European journal of pharmacology. 820
Xanthoceraside, a novel triterpenoid saponin extracted from the husks of Xanthoceras sorbifolia Bunge, has neuroprotective effects in vivo and anti-inflammatory properties in vitro. However, the exact mechanism of xanthoceraside on anti-amyloid beta
Publikováno v:
Planta Medica. 80:262-268
Sodium formononetin-3′-sulphonate is a derivative of the plant isoflavone formononetin. The present study aimed to investigate the neuroprotective and angiogenesis effects of sodium formononetin-3′-sulphonate in vivo and in vitro. Treatment with
Autor:
Mami Hirakawa, Toshitaka Nabeshima, Yuko Mori, Tomoaki Teshigawara, Lu Qiaohui, Kuniaki Saito, Kazuo Kunisawa, Yang Yang, Akihiro Mouri, Yasuko Yamamoto, Li-Bo Zou
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:2
Publikováno v:
European Journal of Pharmacology. 714:23-31
SMND-309 is a novel derivative of salvianolic acid B, and has shown protective effects against rat cortical neuron damage in vitro and in vivo. However the molecular mechanisms through which SMND-309 affords this protection are unclear. The present s
Publikováno v:
Planta Medica. 79:788-791
Two new steroidal glycosides, 1 α ,3 α -dihydroxy-5 β -pregn-16-en-20-one 3- O - α- L-rhamnopyranoside ( 1 ) and 1 β ,3 β ,27-trihydroxycholest-16-en-22-one 1,3-di- O-α- L - rhamnoside ( 2 ), along with seven known steroidal glycosides ( 3 –
Autor:
Yong-Chao Lu, Ai-Xia Liu, He-Feng Huang, Fan Qu, Ya-Jing Tan, Li-Bo Zou, Dan Zhang, Guo-Lian Ding, Ting-Ting Wang, Ping-Ping Lv, Ye Meng, Run-Ju Zhang, Jian-Zhong Sheng
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 97:543-553
Large-conductance calcium-activated potassium channels (BK(Ca) channels) mediate physiological processes in nonexcitable cells.The aim of the study was to determine BK(Ca) channel expression in human endometrium and its role in endometrial receptivit
Autor:
Li Bo Zou, Toshitaka Nabeshima, Takayoshi Mamiya, Hyoung Chum Kim, Lingling Lu, Takashi Ikejima, Akihiro Mouri, Ping Lu
Publikováno v:
Psychopharmacology. 219:181-190
Rationale In Alzheimer’s disease (AD), the deposition of amyloid peptides is invariably associated with oxidative stress and inflammatory responses. Xanthoceraside has anti-inflammatory and antioxidative activities. However, it remains unclear whet