Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Li‐Kai Tsai"'
Autor:
Hsin-Hsiung Chen, Hsin-Tung Yeo, Yun-Hsin Huang, Li-Kai Tsai, Hsing-Jung Lai, Yeou-Ping Tsao, Show-Li Chen
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Background Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron (MN) degeneration, leading to neuromuscular junction (NMJ) dismantling and severe muscle atrophy. The nuclear receptor interaction protein (NRIP) fun
Externí odkaz:
https://doaj.org/article/e80c578ac91c4c2aa3db510bbe57fac1
Autor:
Sung-Ju Hsueh, Chin-Hsien Lin, Ni-Chung Lee, Tung-Ming Chang, Sung-Pin Fan, Wan-De Huang, Yea-Huey Lin, Li-Kai Tsai, Yin-Hsiu Chien, Ming-Jen Lee, Wuh-Liang Hwu, Hsueh Wen Hsueh, Chih-Chao Yang
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-7 (2024)
Abstract Background To investigate the peripheral nervous system involvement in S sialidosis with typical features of myoclonus, seizure, and giant waves in somatosensory evoked potentials suggesting hyperexcitability in the central nervous system. M
Externí odkaz:
https://doaj.org/article/0abe53ded10c4a81bffb009dfc2f1d65
Autor:
Pin-Yan Kuo, Hsin-Hsi Tsai, Bo-Ching Lee, Pu-Tien Chiang, Chia-Ju Liu, Ya-Fang Chen, Jiann-Shing Jeng, Ruoh-Fang Yen, Li-Kai Tsai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Lobar cerebral microbleeds are a characteristic neuroimaging finding in cerebral amyloid angiopathy (CAA) but can also be found in hypertensive arteriolosclerosis. We aimed to investigate whether CAA is more associated with intracortical lob
Externí odkaz:
https://doaj.org/article/c72d08bd7c4040f4b369cb3c6fb6196f
Autor:
Pu‐Tien Chiang, Hsin‐Hsi Tsai, Ruoh‐Fang Yen, Yi‐Chieh Tsai, Chi‐Han Wu, Ching‐Hung Chiu, Li‐Kai Tsai
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 2, Pp 497-507 (2024)
Abstract Objective F‐18‐fluorothymidine (FLT) is a positron emission tomography (PET) tracer for imaging cell proliferation in vivo. We aimed to assess FLT uptake as a marker for cerebral cell proliferation in a rat model of ischemic stroke and p
Externí odkaz:
https://doaj.org/article/5439f013b2dc4e25a55b67edce74b0e4
Publikováno v:
Bioengineering, Vol 11, Iss 10, p 1020 (2024)
This study used epigenomic methylation differential expression analysis to identify primary biomarkers in patients with amyotrophic lateral sclerosis (ALS). We combined electronic medical record datasets from MIMIC-IV (United States) and NHIRD (Taiwa
Externí odkaz:
https://doaj.org/article/824e0ff11ce6429b9ef89a900f74ff7b
Autor:
Sung‐Ju Hsueh, Chi‐Chao Chao, Ta‐Fu Chen, Ya‐Fang Chen, Hsueh‐Wen Hsueh, Li‐Kai Tsai, Wen‐Chau Wu, Sung‐Tsang Hsieh
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 8, Pp 1456-1466 (2023)
Abstract Objective This study aimed to explore the clinical significance of brain imaging signatures in the context of clinical neurological deficits in association with upper and lower motor neuron degeneration in amyotrophic lateral sclerosis (ALS)
Externí odkaz:
https://doaj.org/article/c854fa4275a240a78814a6fda65c39d3
Cerebral amyloid deposition predicts long‐term cognitive decline in hemorrhagic small vessel disease
Autor:
Ya‐Chin Tsai, Hsin‐Hsi Tsai, Chia‐Ju Liu, Sheng‐Sian Lin, Ya‐Fang Chen, Jiann‐Shing Jeng, Li‐Kai Tsai, Ruoh‐Fang Yen
Publikováno v:
Brain and Behavior, Vol 13, Iss 10, Pp n/a-n/a (2023)
Abstract Background To investigate the association between cerebral amyloid deposition and long‐term cognitive outcomes in patients with hemorrhagic small vessel disease (SVD) and survivors of intracerebral hemorrhage (ICH). Methods Patients experi
Externí odkaz:
https://doaj.org/article/cf83a7303a264011a631bee8f787abe7
Publikováno v:
Biomedical Journal, Vol 45, Iss 5, Pp 806-813 (2022)
Background: Few studies documented incidence rates of different types of stroke among patients with polycystic kidney disease (PKD). Methods: We conducted a retrospective cohort study based on the National Health Insurance (NHI) Database of Taiwan. T
Externí odkaz:
https://doaj.org/article/bf7d93ad1f3b4ae4a10ae1db7ee3ad1a
Publikováno v:
Journal of Stroke, Vol 24, Iss 3, Pp 363-371 (2022)
Background and Purpose Cerebral venous flow alterations potentially contribute to age-related white matter changes, but their role in small vessel disease has not been investigated. Methods This study included 297 patients with hypertensive intracere
Externí odkaz:
https://doaj.org/article/f80c2e2ca9e44f71900e212841409f74
Autor:
Ting-Chun Lin, Yi-Chieh Tsai, Yun-An Chen, Tai-Horng Young, Chung-Che Wu, Yung-Hsiao Chiang, Chia-Hsin Kao, Abel Po-Hao Huang, Yi-Hua Hsu, Kai-Yun Chen, Li-Kai Tsai
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Background and purposeIntracerebral hemorrhage (ICH) enhances neurogenesis in the subventricular zone (SVZ); however, the mechanism is not fully understood. We investigated the role of brain-derived neurotrophic factor (BDNF) in post-ICH neurogenesis
Externí odkaz:
https://doaj.org/article/6a417eb602fe4bc997d37849baa5ff77