Zobrazeno 1 - 10
of 1 778
pro vyhledávání: '"Li‐An Chu"'
Autor:
Ya-Hui Lin, Li-Wen Wang, Yen-Hui Chen, Yi-Chieh Chan, Shang-Hsiu Hu, Sheng-Yan Wu, Chi-Shiun Chiang, Guan-Jie Huang, Shang-Da Yang, Shi-Wei Chu, Kuo-Chuan Wang, Chin-Hsien Lin, Pei-Hsin Huang, Hwai-Jong Cheng, Bi-Chang Chen, Li-An Chu
Publikováno v:
eLife, Vol 13 (2024)
Tissue-clearing and labeling techniques have revolutionized brain-wide imaging and analysis, yet their application to clinical formalin-fixed paraffin-embedded (FFPE) blocks remains challenging. We introduce HIF-Clear, a novel method for efficiently
Externí odkaz:
https://doaj.org/article/b239d423825a47b49f63a520e73a8d68
Autor:
Min‐Ren Chiang, Ya‐Hui Lin, Wei‐Jie Zhao, Hsiu‐Ching Liu, Ru‐Siou Hsu, Tsu‐Chin Chou, Tsai‐Te Lu, I‐Chi Lee, Lun‐De Liao, Shih‐Hwa Chiou, Li‐An Chu, Shang‐Hsiu Hu
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract Endogenous signals, namely nitric oxide (NO) and electrons, play a crucial role in regulating cell fate as well as the vascular and neuronal systems. Unfortunately, utilizing NO and electrical stimulation in clinical settings can be challeng
Externí odkaz:
https://doaj.org/article/90072ab15f9842f4872dd52094827b4d
Autor:
Ru-Siou Hsu, Ssu-Ju Li, Jen-Hung Fang, I-Chi Lee, Li-An Chu, Yu-Chun Lo, Yu-Jen Lu, You-Yin Chen, Shang-Hsiu Hu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Traumatic brain injury can cause long-term disability and thus constitutes a substantial healthcare burden worldwide. Here, the authors report a conductive microporous hydrogel to improve angiogenesis and recovery of brain function in traumatic brain
Externí odkaz:
https://doaj.org/article/c79d74b283df479db9b3a0311d6cd647
Publikováno v:
AIP Advances, Vol 13, Iss 1, Pp 015125-015125-7 (2023)
Horizontally stratified flows can be seen in a wide variety of micro-scale engineering problems. Recent studies have shown that diffusion at the interface between two liquids leads to a lateral flow, causing the fluid to rotate around the central axi
Externí odkaz:
https://doaj.org/article/ce0904d15b2549faab7f7efabf007d96
We investigate the strong coupling problem in modified teleparallel gravity theories using the effective field theory (EFT) approach, demonstrating that it is possible to shift the emergence of new degrees of freedom (DoFs) to lower orders in perturb
Externí odkaz:
http://arxiv.org/abs/2410.03422
Autor:
Ya-Chu Chang, Yu-Xiang Peng, Bo-Hua Yu, Henry C. Chang, Pei-Shin Liang, Ting-Yi Huang, Chao-Jie Shih, Li-An Chu, Tzu-Kang Sang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Cells maintain a constant cytoplasm to nucleus volume ratio, although the role of DNA damage is not well explored. Here, the authors use Drosophila to connect TER94, the fly homolog of VCP, to disruption of DNA damage repair, leading to ubiquitinated
Externí odkaz:
https://doaj.org/article/a98e31b8568b4570a73299717fbf8dd4
Autor:
Chen-Yi Wu, Jhih-Gang Jhang, Wan-Syuan Lin, Pei-Huan Chuang, Chih-Wei Lin, Li-An Chu, Ann-Shyn Chiang, Han-Chen Ho, Chih-Chiang Chan, Shu-Yi Huang
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103437- (2021)
Summary: Exosomes are important for cell–cell communication. Deficiencies in the human dihydroceramide desaturase gene, DEGS1, increase the dihydroceramide-to-ceramide ratio and cause hypomyelinating leukodystrophy. However, the disease mechanism r
Externí odkaz:
https://doaj.org/article/d55d5ad4e81547aca45b87af80fcaba8
Autor:
Li-An Chu, Chieh-Han Lu, Shun-Min Yang, Yen-Ting Liu, Kuan-Lin Feng, Yun-Chi Tsai, Wei-Kun Chang, Wen-Cheng Wang, Shu-Wei Chang, Peilin Chen, Ting-Kuo Lee, Yeu-Kuang Hwu, Ann-Shyn Chiang, Bi-Chang Chen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
It has been challenging to perform super-resolution imaging in large volumes due to aberrations encountered. Here, the authors combine single-wavelength Bessel lightsheet localization microscopy with tissue clearing techniques and image neurons acros
Externí odkaz:
https://doaj.org/article/6d9a7b48ec084346b8e85b93cccb6cfe
Autor:
Ye Zhang, Tin Ki Tsang, Eric A. Bushong, Li-An Chu, Ann-Shyn Chiang, Mark H. Ellisman, Jürgen Reingruber, Chih-Ying Su
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
In Drosophila antenna, an unusual non-synaptic form of lateral inhibition occurs between subtypes of compartmentalized olfactory receptor neurons (ORNs). Here, authors show that direct electrical (ephaptic) interactions mediate lateral inhibition bet
Externí odkaz:
https://doaj.org/article/20f6606c86b9456db30454156e24a738
Autor:
Han-Yuan Lin, Li-An Chu, Hsuan Yang, Kuo-Jen Hsu, Yen-Yin Lin, Keng-Hui Lin, Shi-Wei Chu, Ann-Shyn Chiang
Publikováno v:
iScience, Vol 14, Iss , Pp 164-170 (2019)
Summary: Recently, many super-resolution technologies have been demonstrated, significantly affecting biological studies by observation of cellular structures down to nanometer precision. However, current super-resolution techniques mostly rely on wa
Externí odkaz:
https://doaj.org/article/79f6e615137948c48d8c40f17ff99381