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Epigenetic Regulation of Fanconi Anemia Genes Implicates PRMT5 Blockage as a Strategy for Tumor Chemosensitization.

Autor: Du C; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina.; School of Medicine, Southern University of Science and Technology, and Southern University of Science and Technology Hospital, Nanshan District, Shenzhen, Guangdong, China., Li SW; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina., Singh SX; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina.; Pathology Graduate Program, Duke University Medical Center, Durham, North Carolina., Roso K; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina., Sun MA; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina.; Pathology Graduate Program, Duke University Medical Center, Durham, North Carolina., Pirozzi CJ; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina., Yang R; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina.; Department of Pathology, Duke University Medical Center, Durham, North Carolina., Li JL; Integrative Bioinformatics Support Group, National Institute of Environmental Health Sciences, Durham, North Carolina., He Y; The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina. yiping.he@duke.edu.; Department of Pathology, Duke University Medical Center, Durham, North Carolina.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2021 Dec; Vol. 19 (12), pp. 2046-2056. Date of Electronic Publication: 2021 Sep 14.