Immunomodulatory Effect of Polysaccharides from the Mushroom-Forming Basidiomycete Gymnopilus imperialis (Agaricomycetes, Basidiomycota)

Autor: Lhaís A. Caldas, Patricia D. Santos, Elaine R. Carbonero, Marisa Ionta, Marta Miyazawa, Ester S. Caixeta, Antonio M. Fregnan, Bianca Barros Nóbrega, Maria Carolina B. Di Medeiros, Nelson Menolli, Douglas M. M. Soares, Cassius V. Stevani, Patricia Sartorelli

Publikováno v: Pharmaceuticals, Vol 15, Iss 10, p 1179 (2022)

Gymnopilus consists of a widely distributed genus of basidiomycetes, especially in tropical regions of the world, such as Japan, Australia, Paraguay, and Brazil. This genus biosynthesizes interesting bioactive compounds, such as sesquiterpenoids, oli

Externí odkaz: https://doaj.org/article/cda1407a5f3b497ca9ee60698bf545d8

Sesquiterpene Lactones from Calea pinnatifida: Absolute Configuration and Structural Requirements for Antitumor Activity

Autor: Lhaís Araújo Caldas, Mariana T. Rodrigues, Andrea N. L. Batista, João M. Batista, João H. G. Lago, Marcelo J. P. Ferreira, Ileana G. S. Rubio, Patricia Sartorelli

Publikováno v: Molecules, Vol 25, Iss 13, p 3005 (2020)

This work describes the chromatographic fractionation of the aerial parts of Calea pinnatifida and the structural characterization and determination of the absolute configuration of the isolated compounds as well as their antitumor potential. The HPL

Externí odkaz: https://doaj.org/article/6de0a8a91fdd4765863317059da008e3

Metabolomics of the wild mushroom Gymnopilus imperialis (Agaricomycetes, Basidiomycota) by UHPLC-HRMS/MS analysis and molecular network

Autor: Lhaís Araújo Caldas, Douglas M. M. Soares, Nelson Menolli, Cassius V. Stevani, Patricia Sartorelli

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Gymnopilus consists in a widely distributed genus of mushroom-forming fungi, especially in tropical regions of the world. Literature on Gymnopilus representatives reports the presence of oligoisoprenoids, and styrylpyrones. Considering the large numb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848113e97ec8bfc38c5e1f64f3a865ce

Sesquiterpene Lactones from Calea pinnatifida: Absolute Configuration and Structural Requirements for Antitumor Activity

Autor: Mariana T. Rodrigues, Marcelo J. P. Ferreira, Ileana Gabriela Sanchez Rubio, Lhaís Araújo Caldas, João M. Batista, Andrea N. L. Batista, Patricia Sartorelli, João Henrique G. Lago

Publikováno v: Molecules
Volume 25
Issue 13
Molecules, Vol 25, Iss 3005, p 3005 (2020)

This work describes the chromatographic fractionation of the aerial parts of Calea pinnatifida and the structural characterization and determination of the absolute configuration of the isolated compounds as well as their antitumor potential. The HPL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3d8ef5084958d5a64afec57d821da9

Calein C, a Sesquiterpene Lactone Isolated From Calea Pinnatifida (Asteraceae), Inhibits Mitotic Progression and Induces Apoptosis in MCF-7 Cells

Autor: Guilherme Álvaro Ferreira-Silva, Marisa Ionta, Marcelo J. P. Ferreira, Lhaís Araújo Caldas, Renato de Oliveira Horvath, Patricia Sartorelli

Publikováno v: Frontiers in Pharmacology, Vol 9 (2018)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Pharmacology

Breast cancer is the most common cancer in women worldwide. Estrogen receptor-positive (ER+) breast cancer represents approximately 75% of diagnosed cases, while 15–20% of them are triple-negative (TN). Although there have been improvements in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7cab30377bfcdb9a02c6e708f26588
https://www.frontiersin.org/article/10.3389/fphar.2018.01191/full