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Reduction of mechanical loading in tendons induces heterotopic ossification and activation of the β-catenin signaling pathway.

Autor: Wang T; Centre for Orthopaedic Translational Research, School of Biomedical Sciences, University of Western Australia, Nedlands, Australia.; Division of Orthopaedic Surgery, Department of Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China., Chen P; Centre for Orthopaedic Translational Research, School of Biomedical Sciences, University of Western Australia, Nedlands, Australia., Chen L; Centre for Orthopaedic Translational Research, School of Biomedical Sciences, University of Western Australia, Nedlands, Australia., Zhou Y; Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Australia., Wang A; Centre for Orthopaedic Translational Research, School of Biomedical Sciences, University of Western Australia, Nedlands, Australia.; Sir Charles Gairdner Hospital, Perth, Australia., Zheng Q; Division of Orthopaedic Surgery, Department of Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China., Mitchell CA; Centre for Orthopaedic Translational Research, School of Biomedical Sciences, University of Western Australia, Nedlands, Australia., Leys T; Sir Charles Gairdner Hospital, Perth, Australia., Tuan RS; Institute for Tissue Engineering and Regenerative Medicine, The Chinese University of Hong Kong, Hong Kong., Zheng MH; Division of Orthopaedic Surgery, Department of Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.

Publikováno v: Journal of orthopaedic translation [J Orthop Translat] 2021 May 18; Vol. 29, pp. 42-50. Date of Electronic Publication: 2021 May 18 (Print Publication: 2021).

Cellular senescence impairs tendon extracellular matrix remodeling in response to mechanical unloading.

Autor: Stowe, Emma J.¹ (AUTHOR), Keller, Madelyn R.¹ (AUTHOR), Connizzo, Brianne K.¹ (AUTHOR) connizzo@bu.edu

Publikováno v: Aging Cell. Nov2024, Vol. 23 Issue 11, p1-15. 15p.

Load-induced regulation of tendon homeostasis by SPARC, a genetic predisposition factor for tendon and ligament injuries.

Autor: Wang T; Centre for Orthopaedic Translational Research, Medical School, University of Western Australia, Nedlands, Western Australia 6009,Australia.; Division of Orthopaedic Surgery, Department of Surgery, Guangdong Provincial People'sHospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510000, China., Wagner A; Institute of Tendon and Bone Regeneration, Paracelsus Medical University-Spinal Cord Injury and Tissue Regeneration Center Salzburg, 5020 Salzburg, Austria.; Austrian Cluster for Tissue Regeneration, 1200 Vienna, Austria., Gehwolf R; Institute of Tendon and Bone Regeneration, Paracelsus Medical University-Spinal Cord Injury and Tissue Regeneration Center Salzburg, 5020 Salzburg, Austria.; Austrian Cluster for Tissue Regeneration, 1200 Vienna, Austria., Yan W; State Key Laboratory of Pharmaceutical Biotechnology, Department of Sports Medicine and Adult Reconstructive Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China., Passini FS; University Hospital Balgrist, University of Zurich, Zürich, Switzerland.; Institute for Biomechanics, ETH Zurich, 8008 Zürich, Switzerland., Thien C; Centre for Orthopaedic Translational Research, Medical School, University of Western Australia, Nedlands, Western Australia 6009,Australia., Weissenbacher N; Institute of Tendon and Bone Regeneration, Paracelsus Medical University-Spinal Cord Injury and Tissue Regeneration Center Salzburg, 5020 Salzburg, Austria.; Austrian Cluster for Tissue Regeneration, 1200 Vienna, Austria., Lin Z; Centre for Orthopaedic Translational Research, Medical School, University of Western Australia, Nedlands, Western Australia 6009,Australia.; Division of Orthopaedic Surgery, Department of Surgery, Guangdong Provincial People'sHospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510000, China., Lehner C; Institute of Tendon and Bone Regeneration, Paracelsus Medical University-Spinal Cord Injury and Tissue Regeneration Center Salzburg, 5020 Salzburg, Austria.; Austrian Cluster for Tissue Regeneration, 1200 Vienna, Austria., Teng H; Laboratory for Bone and Joint Disease, Model Animal Research Center (MARC), Nanjing University, Nanjing 210008, China., Wittner C; Computed Tomography Research Group, University of Applied Sciences Upper Austria, 4600 Wels, Austria., Zheng Q; Division of Orthopaedic Surgery, Department of Surgery, Guangdong Provincial People'sHospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510000, China., Dai J; State Key Laboratory of Pharmaceutical Biotechnology, Department of Sports Medicine and Adult Reconstructive Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China., Ni M; Centre for Orthopaedic Translational Research, Medical School, University of Western Australia, Nedlands, Western Australia 6009,Australia.; Department of Orthopaedics, General Hospital of Chinese People's Liberation Army, Beijing 100853, China., Wang A; Centre for Orthopaedic Translational Research, Medical School, University of Western Australia, Nedlands, Western Australia 6009,Australia., Papadimitriou J; Centre for Orthopaedic Translational Research, Medical School, University of Western Australia, Nedlands, Western Australia 6009,Australia.; PathWest Laboratories, Nedlands, Western Australia 6009, Australia., Leys T; Centre for Orthopaedic Translational Research, Medical School, University of Western Australia, Nedlands, Western Australia 6009,Australia., Tuan RS; Center for Cellular and Molecular Engineering, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.; Institute for Tissue Engineering and Regenerative Medicine, Chinese University of Hong Kong, Hong Kong SAR, China., Senck S; Computed Tomography Research Group, University of Applied Sciences Upper Austria, 4600 Wels, Austria., Snedeker JG; University Hospital Balgrist, University of Zurich, Zürich, Switzerland.; Institute for Biomechanics, ETH Zurich, 8008 Zürich, Switzerland., Tempfer H; Institute of Tendon and Bone Regeneration, Paracelsus Medical University-Spinal Cord Injury and Tissue Regeneration Center Salzburg, 5020 Salzburg, Austria.; Austrian Cluster for Tissue Regeneration, 1200 Vienna, Austria., Jiang Q; State Key Laboratory of Pharmaceutical Biotechnology, Department of Sports Medicine and Adult Reconstructive Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China. andreas.traweger@pmu.ac.at minghao.zheng@uwa.edu.au qingj@nju.edu.cn., Zheng MH; Centre for Orthopaedic Translational Research, Medical School, University of Western Australia, Nedlands, Western Australia 6009,Australia. andreas.traweger@pmu.ac.at minghao.zheng@uwa.edu.au qingj@nju.edu.cn.; Perron Institute for Neurological and Translational Science, Nedlands, Western Australia 6009, Australia., Traweger A; Institute of Tendon and Bone Regeneration, Paracelsus Medical University-Spinal Cord Injury and Tissue Regeneration Center Salzburg, 5020 Salzburg, Austria. andreas.traweger@pmu.ac.at minghao.zheng@uwa.edu.au qingj@nju.edu.cn.; Austrian Cluster for Tissue Regeneration, 1200 Vienna, Austria.

Publikováno v: Science translational medicine [Sci Transl Med] 2021 Feb 24; Vol. 13 (582).

Recent advances in near-infrared photobiomodulation for the intervention of acquired brain injury.

Autor: Huang, Yujing^1,2 (AUTHOR), Zhang, Yujing^1,2 (AUTHOR), Yang, Chen^1,2 (AUTHOR), Xu, Mengze^2,3 (AUTHOR), Yuan, Zhen^1,2 (AUTHOR) zhenyuan@um.edu.mo

Publikováno v: Journal of Innovative Optical Health Sciences. Aug2024, p1. 27p. 5 Illustrations.