Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Leyre, Urigüen"'
The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls
Autor:
Carlos Costas-Insua, Alba Hermoso-López, Estefanía Moreno, Carlos Montero-Fernández, Alicia Álvaro-Blázquez, Irene B Maroto, Andrea Sánchez-Ruiz, Rebeca Diez-Alarcia, Cristina Blázquez, Paula Morales, Enric I Canela, Vicent Casadó, Leyre Urigüen, Gertrudis Perea, Luigi Bellocchio, Ignacio Rodríguez-Crespo, Manuel Guzmán
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 755-783 (2024)
Abstract Cereblon/CRBN is a substrate-recognition component of the Cullin4A-DDB1-Roc1 E3 ubiquitin ligase complex. Destabilizing mutations in the human CRBN gene cause a form of autosomal recessive non-syndromic intellectual disability (ARNSID) that
Externí odkaz:
https://doaj.org/article/5c7b69f9446144719e20ce1f4a631547
Autor:
Silvia Iñiguez-Barrio, Paula Unzueta-Larrinaga, Luis Callado, Rebeca Diez-Alarcia, Guadalupe Rivero, Leyre Urigüen
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S583-S584 (2023)
Externí odkaz:
https://doaj.org/article/10d484d9402b48e3b0992bec34775e8a
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S655-S656 (2023)
Externí odkaz:
https://doaj.org/article/01e299401e7947a79f81bb1f39e4d8e7
Autor:
Alba Hermoso-López, Carlos Costas-Insua, Carlos Montero-Fernández, Estefanía Moreno, Alicia Álvaro-Blázquez, David Martín-Gutiérrez, Irene B. Maroto-Martínez, Rebeca Diez-Alarcia, Leyre Urigüen, Vicent Casadó, Ignacio Rodríguez-Crespo, Manuel Guzmán
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S848- (2023)
Externí odkaz:
https://doaj.org/article/b668f7103ab240249d28d67435c8975d
Autor:
Inés Ibarra-Lecue, Rebeca Diez-Alarcia, Benito Morentin, J. Javier Meana, Luis F. Callado, Leyre Urigüen
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The mechanistic target of rapamycin (also known as mammalian target of rapamycin) (mTOR)-dependent signaling pathway plays an important role in protein synthesis, cell growth, and proliferation, and has been linked to the development of the central n
Externí odkaz:
https://doaj.org/article/b1b5ae7dfa0d44109ae0b30e6289550f
Autor:
Paula Unzueta-Larrinaga, Rocío Barrena-Barbadillo, Inés Ibarra-Lecue, Igor Horrillo, Aitor Villate, Maria Recio, J. Javier Meana, Rebeca Diez-Alarcia, Oihane Mentxaka, Rafael Segarra, Nestor Etxebarria, Luis F. Callado, Leyre Urigüen
Publikováno v:
Molecular Neurobiology.
The study of psychiatric and neurological diseases requires the substrate in which the disorders occur, that is, the nervous tissue. Currently, several types of human bio-specimens are being used for research, including postmortem brains, cerebrospin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f4d71672c27f733efcbafd38401af81
https://doi.org/10.1007/s12035-023-03363-2
https://doi.org/10.1007/s12035-023-03363-2
Autor:
Inés Ibarra‐Lecue, Paula Unzueta‐Larrinaga, Rocío Barrena‐Barbadillo, Aitor Villate, Igor Horrillo, Begoña Mendivil, Miguel A. Landabaso, J. Javier Meana, Nestor Etxebarria, Luis F. Callado, Leyre Urigüen
Cannabis use disorder is frequent in schizophrenia patients, and it is associated with an earlier age of onset and poor schizophrenia prognosis. Serotonin 2A receptors (5-HT2AR) have been involved in psychosis and, like Akt kinase, are known to be mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19a3ee482841a118633eabcc0d00bef
http://hdl.handle.net/10810/58543
http://hdl.handle.net/10810/58543
Autor:
Rebeca Diez-Alarcia, Inés Ibarra-Lecue, Ángela Patricia López-Cardona, Javier Meana, Alfonso Gutierrez-Adán, Luis F Callado, Ekaitz Agirregoitia, Leyre Urigüen
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Cannabinoid receptors are able to couple to different families of G-proteins when activated by an agonist drug. It has been suggested that different intracellular responses may be activated depending on the ligand. The goal of the present study was t
Externí odkaz:
https://doaj.org/article/5023637e43f04ecdba72c303652c6b2a
Autor:
Anissa Bara, Luis F. Callado, Manenti Cristina, Parolaro Daniela, Adán de Salas-Quiroga, Anthony English, Zamberletti Erica, Roberto Frau, Ismael Galve-Roperh, Gabriele Giua, Manuel Guzmán, Tibor Harkany, Yuto Hasegawa, Yasmin L. Hurd, Atsushi Kamiya, Erik Keimpema, Benjamin Land, Steven R. Laviolette, Ken Mackie, Antonia Manduca, Olivier J.J. Manzoni, Gabaglio Marina, Ashley E. Marquardt, Margaret M. McCarthy, Miriam Melis, Kateryna Murlanova, A.-L. Pélissier-Alicot, Mikhail V. Pletnikov, Samuel Simón Sánchez, Andrew Scheyer, Nephi Stella, Rubino Tiziana, Viviana Trezza, Paula Unzueta-Larrinaga, Leyre Urigüen, Jonathan W. VanRyzin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb9b6b50219ff4faac5c4992d785cc3f
https://doi.org/10.1016/b978-0-12-823490-7.09994-9
https://doi.org/10.1016/b978-0-12-823490-7.09994-9