Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Leyla Esfandiari"'
Autor:
Maulee Sheth, Manju Sharma, Maria Lehn, HasanAl Reza, Takanori Takebe, Vinita Takiar, Trisha Wise-Draper, Leyla Esfandiari
Publikováno v:
APL Bioengineering, Vol 8, Iss 3, Pp 036106-036106-13 (2024)
Extracellular biophysical cues such as matrix stiffness are key stimuli tuning cell fate and affecting tumor progression in vivo. However, it remains unclear how cancer spheroids in a 3D microenvironment perceive matrix mechanical stiffness stimuli a
Externí odkaz:
https://doaj.org/article/6437b49be11f4c28824d29df5db0a4ae
Autor:
Yara Izhiman, Leyla Esfandiari
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Peripheral nerve injuries lead to significant morbidity and adversely affect quality of life. The peripheral nervous system harbors the unique trait of autonomous regeneration; however, achieving successful regeneration remains uncertain. Research co
Externí odkaz:
https://doaj.org/article/5b1b151a33c24d5d87379207ad8076aa
Autor:
Manju Sharma, Maulee Sheth, Holly M. Poling, Damaris Kuhnell, Scott M. Langevin, Leyla Esfandiari
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Nano-scale extracellular vesicles are lipid-bilayer delimited particles that are naturally secreted by all cells and have emerged as valuable biomarkers for a wide range of diseases. Efficient isolation of small extracellular vesicles while
Externí odkaz:
https://doaj.org/article/b783d98f56b34dadad099e28bdb3ec8d
Autor:
Jennifer A. Westphal, Andrew E. Bryan, Maksym Krutko, Leyla Esfandiari, Stacey C. Schutte, Greg M. Harris
Publikováno v:
Biomimetics, Vol 9, Iss 1, p 2 (2023)
In this work, electrospun polyvinylidene-trifluoroethylene (PVDF-TrFE) was utilized for its biocompatibility, mechanics, and piezoelectric properties to promote Schwann cell (SC) elongation and sensory neuron (SN) extension. PVDF-TrFE electrospun sca
Externí odkaz:
https://doaj.org/article/673a3fc4420f4bc6b33c558d107d5421
Autor:
Maulee Sheth, Leyla Esfandiari
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cancer is primarily a disease of dysregulation – both at the genetic level and at the tissue organization level. One way that tissue organization is dysregulated is by changes in the bioelectric regulation of cell signaling pathways. At the basis o
Externí odkaz:
https://doaj.org/article/edbd6d44a4f340e585e9c8bc64145672
Autor:
Leilei Shi, Leyla Esfandiari
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270844 (2022)
Electrical Impedance Spectroscopy (EIS) is a non-invasive and label-free technology that can characterize and discriminate cells based on their dielectric properties at a wide range of frequency. This characterization method has not been utilized for
Externí odkaz:
https://doaj.org/article/22d65a63c9a7443b925842029cd3e4e2
Autor:
Yuqian Zhang, Kazutoshi Murakami, Vishnupriya J. Borra, Mehmet Ozgun Ozen, Utkan Demirci, Takahisa Nakamura, Leyla Esfandiari
Publikováno v:
Biosensors, Vol 12, Iss 2, p 104 (2022)
Extracellular vesicles (EVs) have gained considerable attention as vital circulating biomarkers since their structure and composition resemble the originating cells. The investigation of EVs’ biochemical and biophysical properties is of great impor
Externí odkaz:
https://doaj.org/article/0b3140f327394037943365cefaca9e28
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract An insulator-based dielectrophoresis (iDEP) is a label-free method that has been extensively utilized for manipulation of nanoparticles, cells, and biomolecules. Here, we present a new iDEP approach that can rapidly trap nanoparticles at the
Externí odkaz:
https://doaj.org/article/7079644c2a114d5dacd1585e84e37da4
Autor:
Leilei Shi, Leyla Esfandiari
Publikováno v:
Micromachines, Vol 12, Iss 1, p 11 (2020)
Electrical Impedance Spectroscopy (EIS) has been widely used as a label-free and rapid characterization method for the analysis of cells in clinical research. However, the related work on exosomes (40–150 nm) and the particles of similar size has n
Externí odkaz:
https://doaj.org/article/99fc3476802f457097c93b00f1877654
Autor:
Leyla Esfandiari, Siqing Wang, Siqi Wang, Anisha Banda, Michael Lorenzini, Gayane Kocharyan, Harold G. Monbouquette, Jacob J. Schmidt
Publikováno v:
Biosensors, Vol 6, Iss 3, p 37 (2016)
A PCR-free, optics-free device is used for the detection of Escherichia coli (E. coli) 16S rRNA at 10 fM, which corresponds to ~100–1000 colony forming units/mL (CFU/mL) depending on cellular rRNA levels. The development of a rapid, sensitive, and
Externí odkaz:
https://doaj.org/article/8985c0ffbcb2422596f98cff628444ad