Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Leyla A Ovchinnikova"'
Autor:
Yakov A. Lomakin, Leyla A. Ovchinnikova, Stanislav S. Terekhov, Samir S. Dzhelad, Igor Yaroshevich, Ilgar Mamedov, Anastasia Smirnova, Tatiana Grigoreva, Igor E. Eliseev, Ioanna N. Filimonova, Yuliana A. Mokrushina, Victoria Abrikosova, Maria P. Rubtsova, Nikita N. Kostin, Maria A. Simonova, Tatiana V. Bobik, Natalia L. Aleshenko, Alexander I. Alekhin, Vitali M. Boitsov, Hongkai Zhang, Ivan V. Smirnov, Yuri P. Rubtsov, Alexander G. Gabibov
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Identifying high-affinity antibodies in human serum is challenging due to extremely low number of circulating B cells specific to the desired antigens. Delays caused by a lack of information on the immunogenic proteins of viral origin hamper
Externí odkaz:
https://doaj.org/article/9a1b2eaaa96441b3b3acb5378dc413ce
Autor:
Yakov A. Lomakin, Ivan V. Zvyagin, Leyla A. Ovchinnikova, Marsel R. Kabilov, Dmitriy B. Staroverov, Artem Mikelov, Alexey E. Tupikin, Maria Y. Zakharova, Nadezda A. Bykova, Vera S. Mukhina, Alexander V. Favorov, Maria Ivanova, Taras Simaniv, Yury P. Rubtsov, Dmitriy M. Chudakov, Maria N. Zakharova, Sergey N. Illarioshkin, Alexey A. Belogurov, Alexander G. Gabibov
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundB lymphocytes play a pivotal regulatory role in the development of the immune response. It was previously shown that deficiency in B regulatory cells (Bregs) or a decrease in their anti-inflammatory activity can lead to immunological dysfun
Externí odkaz:
https://doaj.org/article/d528caab928e4513a84bb21ec05cf1a7
Publikováno v:
Life, Vol 12, Iss 11, p 1943 (2022)
Extracellular vesicles (EVs) represent membrane-enclosed structures that are likely to be secreted by all living cell types in the animal organism, including cells of peripheral (PNS) and central nervous systems (CNS). The ability to cross the blood-
Externí odkaz:
https://doaj.org/article/c84c458b1fa44be696e35060c285193f
Autor:
Viktoria A. Abrikosova, Yuliana A. Mokrushina, Leyla A. Ovchinnikova, Ekaterina N. Larina, Stanislav S. Terekhov, Margarita N. Baranova, Yakov A. Lomakin, Dmitriy S. Balabashin, Tatyana V. Bobik, Elena N. Kaliberda, Vera D. Knorre, Marina V. Shpilevaya, Teimur T. Aliev, Dmitry G. Deryabin, Arfenya E. Karamova, Alexey A. Kubanov, Mikhail P. Kirpichnikov, Ivan V. Smirnov
Publikováno v:
Acta Naturae. 15:13-18
Pemphigus vulgaris is a severe, socially significant autoimmune disease associated with autoantibodies to the desmoglein 3 antigen. The disease affects all age groups, beginning at 18 years of age; the mortality rate of pemphigus can reach as high as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8975b86a0a5f6e97b8c1003e8ed333d6
https://doi.org/10.32607/actanaturae.11890
https://doi.org/10.32607/actanaturae.11890
Multiple Sclerosis Is Associated with Immunoglobulin Germline Gene Variation of Transitional B Cells
Autor:
Yakov A. Lomakin, Leyla A. Ovchinnikova, M. N. Zakharova, M. V. Ivanova, T. O. Simaniv, M. R. Kabilov, N. A. Bykova, V. S. Mukhina, A. N. Kaminskaya, A. E. Tupikin, M. Y. Zakharova, A. V. Favorov, S. N. Illarioshkin, A. A. Belogurov, A. G. Gabibov
Publikováno v:
Acta Naturae. 14:84-93
The regulatory functions of the B-cell compartment play an important role in the development and suppression of the immune response. Disruption of their anti-inflammatory functions may lead to the acceleration of immunopathological processes, and to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6333b08471f620eab1db158c616539d5
https://doi.org/10.32607/actanaturae.11794
https://doi.org/10.32607/actanaturae.11794
Autor:
Leyla A. Ovchinnikova, Stanislav S. Terekhov, Rustam H. Ziganshin, Dmitriy V. Bagrov, Ioanna N. Filimonova, Arthur O. Zalevsky, Yakov A. Lomakin
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 768 (2021)
Delivering protein therapeutics specifically into target cells and tissues is a promising avenue in medicine. Advancing this process will significantly enhance the efficiency of the designed drugs. In this regard, natural membrane-based systems are o
Externí odkaz:
https://doaj.org/article/53c7b7acfe7c4de3a73871e6d3845534
Autor:
Irina P. Balmasova, Evgenii I. Olekhnovich, Ksenia M. Klimina, Anna A. Korenkova, Maria T. Vakhitova, Elmar A. Babaev, Leyla A. Ovchinnikova, Yakov A. Lomakin, Ivan V. Smirnov, Victor N. Tsarev, Ashot M. Mkrtumyan, Alexey A. Belogurov, Alexander G. Gabibov, Elena N. Ilina, Sergey D. Arutyunov
Publikováno v:
Pathogens, Vol 10, Iss 5, p 504 (2021)
Since periodontitis and type 2 diabetes mellitus are complex diseases, a thorough understanding of their pathogenesis requires knowing the relationship of these pathologies with other disorders and environmental factors. In this study, the representa
Externí odkaz:
https://doaj.org/article/f0365e816eb84d42b61522990f44b106
Autor:
Irina A. Ishina, Ioanna N. Filimonova, Maria Y. Zakharova, Leyla A. Ovchinnikova, Azad E. Mamedov, Yakov A. Lomakin, Alexey A. Belogurov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6258 (2020)
Effective and versatile screening of the peptide ligands capable of selectively binding to diverse receptors is in high demand for the state-of-the-art technologies in life sciences, including probing of specificity of the cell surface receptors and
Externí odkaz:
https://doaj.org/article/a25c2fa5f8e44ff5b200a576a2e99e46
Autor:
Teimour K. Aliev, Alexander G. Gabibov, Ioanna N. Filimonova, Dmitriy S. Balabashin, Leyla A. Ovchinnikova, Maria Y. Zakharova, Yakov A. Lomakin
Publikováno v:
Acta Naturae
Targeting protein therapeutics to specific cells and tissues is a major challenge in modern medicine. Improving the specificity of protein therapeutic delivery will significantly enhance efficiency in drug development. One of the promising tools for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321b18b9d443745e85692cc49d628360
https://doi.org/10.32607/actanaturae.11478
https://doi.org/10.32607/actanaturae.11478
Autor:
Alexey A. Belogurov, Marsel R. Kabilov, Stanislav S. Terekhov, Andrey D. Prjibelski, Konstantin Severinov, Leyla A. Ovchinnikova, Alexander G. Gabibov, Alexey E. Tupikin, Igor E. Eliseev, Yakov A. Lomakin, Sidney Altman, Ivan V. Smirnov
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance DNA libraries are predisposed to template mispairing during conventional “bulk” PCR, leading to the loss of unique sequences. The latter is facilitated by the nonuniform distribution of templates frequently observed in DNA libraries.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1c0c5e0c8f6899be1c71d5f142b42e
https://doi.org/10.1073/pnas.2017138117
https://doi.org/10.1073/pnas.2017138117