Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Leyi, Lin"'
Autor:
Heather Friberg, Morgan Gargulak, Amanda Kong, Leyi Lin, Luis J. Martinez, Alexander C. Schmidt, Robert M. Paris, Richard G. Jarman, Clemente Diaz, Stephen J. Thomas, Philippe Moris, Jeffrey R. Currier
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract The increasing global impact of dengue underscores the need for a dengue virus (DENV) vaccine. We assessed B-cell and T-cell responses following vaccination with four formulations of a tetravalent dengue purified inactivated vaccine (DPIV) i
Externí odkaz:
https://doaj.org/article/2046e228a49043bda2bf6939924cdb61
Autor:
Noemia S. Lima, Damee Moon, Samuel Darko, Rafael A. De La Barrera, Leyi Lin, Michael A. Koren, Richard G. Jarman, Kenneth H. Eckels, Stephen J. Thomas, Nelson L. Michael, Kayvon Modjarrad, Daniel C. Douek, Lydie Trautmann
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The epidemic spread of Zika virus (ZIKV), associated with devastating neurologic syndromes, has driven the development of multiple ZIKV vaccines candidates. An effective vaccine should induce ZIKV-specific T cell responses, which are shown to improve
Externí odkaz:
https://doaj.org/article/8198cc4f078b42baad26df95ded2ec3c
Autor:
Heather Friberg, Luis J. Martinez, Leyi Lin, Jason M. Blaylock, Rafael A. De La Barrera, Alan L. Rothman, J. Robert Putnak, Kenneth H. Eckels, Stephen J. Thomas, Richard G. Jarman, Jeffrey R. Currier
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT Dengue is the most prevalent arboviral disease afflicting humans, and a vaccine appears to be the most rational means of control. Dengue vaccine development is in a critical phase, with the first vaccine licensed in some countries where deng
Externí odkaz:
https://doaj.org/article/9a70ddf949f2464fbfa4032091e25a8f
Autor:
Kristopher M, Paolino, Jason A, Regules, James E, Moon, Richard C, Ruck, Jason W, Bennett, Shon A, Remich, Kristin T, Mills, Leyi, Lin, Cadeidre N, Washington, Ghariwayne A, Fornillos, Changhong Y, Lindsey, Kristan A, O'Brien, Meng, Shi, R, Mark Jones, Brian J, Green, Stephen, Tottey, Jessica A, Chichester, Stephen J, Streatfield, Vidadi, Yusibov
Publikováno v:
Vaccine. 40:1864-1871
The potential use of Bacillus anthracis as a bioterrorism weapon requires a safe and effective vaccine that can be immediately distributed for mass vaccination. Protective antigen (PA), a principal component of virulence factors edema toxin and letha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe3a4cfd8259275aee5d7324600c5a2
https://doi.org/10.1016/j.vaccine.2022.01.047
https://doi.org/10.1016/j.vaccine.2022.01.047
Autor:
Paul B. Keiser, Michael Koren, Kenneth H. Eckels, Naomi E. Aronson, Jeffrey R. Currier, Erica L Sondergaard, Louis E. Jasper, Leyi Lin, Heather Friberg, Richard G. Jarman, Marvin J Sklar, Rafael De La Barrera, Gregory D. Gromowski, Stephen J. Thomas, Timothy P. Endy, Kristopher M. Paolino
Publikováno v:
The Journal of Infectious Diseases. 223:1707-1716
Background Dengue is a global health problem and the development of a tetravalent dengue vaccine with durable protection is a high priority. A heterologous prime-boost strategy has the advantage of eliciting immune responses through different mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77f2d17951c747fb028c7b3fb42e622
https://doi.org/10.1093/infdis/jiaa603
https://doi.org/10.1093/infdis/jiaa603
Autor:
Leyi Lin, Kenneth H. Eckels, Dongliang Wang, Louis E. Jasper, Stephen J. Thomas, Kristopher M Paolino, Mark Abbott, Lisa Ware, Heather Friberg, Mark Polhemus, Rafael A De La Barra, Richard G. Jarman, Donald C. Blair, Michelle Klick, Jeffrey R. Currier, Timothy P. Endy, Wiriya Rutvisuttinunt, Greg Gromowski
Publikováno v:
The Journal of Infectious Diseases. 223:258-267
Background Dengue human infection models (DHIM) have been used as a safe means to test the viability of prophylaxis and therapeutics. Methods A phase 1 study of 12 healthy adult volunteers using a challenge virus, DENV-1-LVHC strain 45AZ5, was perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9793c4b76c95a3ce3c07b6c8a278a8
https://doi.org/10.1093/infdis/jiaa351
https://doi.org/10.1093/infdis/jiaa351
Autor:
Robert Paris, Maribel Campos, Kenneth H. Eckels, Alexander C. Schmidt, Luis J. Martinez, Richard G. Jarman, Irma Febo, Clemente Diaz, David W. Vaughn, Edith Lepine, Michael Koren, Rafael De La Barrera, Stephen J. Thomas, Todd M. Wilson, Leyi Lin
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Four formulations of an investigational tetravalent dengue purified inactivated vaccine, administered as two doses one month (M) apart, were previously shown to be immunogenic and well-tolerated up to M13 of the phase I study NCT01702857. Here, we re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe0676ffedccab546eaacc8857f86a2
https://doi.org/10.4269/ajtmh.19-0461
https://doi.org/10.4269/ajtmh.19-0461
Autor:
Philippe Moris, Richard G. Jarman, Edith Lepine, Leyi Lin, Rafael De La Barrera, Heather Friberg, Paul B. Keiser, Monica A. McArthur, Robert Paris, Kenneth H. Eckels, Alexander C. Schmidt, Michael Koren, David W. Vaughn, Stephen J. Thomas, Jeffrey R. Currier, Kirsten E. Lyke
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Dengue disease and its causative agents, the dengue viruses (DENV-1–4), cause high morbidity in tropical and subtropical regions. We evaluated three dosing regimens of the investigational tetravalent AS03B-adjuvanted dengue-purified inactivated vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1801a3e727660873b0bc343dd681d2
http://europepmc.org/articles/PMC7356407
http://europepmc.org/articles/PMC7356407
Autor:
Haitao Zheng, Leyi Lin, Yosuke Okezaki, Ryushi Kawakami, Haruhiko Sakuraba, Toshihisa Ohshima, Keiichi Takagi, Shin-ichiro Suye
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 1, Iss 1, Pp 135-141 (2010)
A glassy carbon electrode (GC) was modified by multi-walled carbon nanotubes (MWCNTs). The modified electrode showed a pair of redox peaks that resulted from the oxygen-containing functional groups on the nanotube surface. A recombinant thermostable
Externí odkaz:
https://doaj.org/article/c96944ba24e14f52aa672a431c345c4c
Autor:
Leyi, Lin, Zhiping, Su, Haishan, Zhang, Guowen, Zhou, Haonan, Zhou, Junli, Ren, Xiaoying, Wang, Chuanfu, Liu, Xiaohui, Wang
Publikováno v:
Carbohydrate Polymers. 291:119479
The increasing environmental burden generated by disposable plastic wastes makes the development of sustainable substitute materials an emergent task. As one of the most abundant bioresources, chitosan (CS) has been considered as a potential candidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5fcb44928e830117838518e021f1af6
https://doi.org/10.1016/j.carbpol.2022.119479
https://doi.org/10.1016/j.carbpol.2022.119479