Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Lexi Ding"'
Autor:
Chao Wang, Yaqiong An, Zhaohua Xia, Xuezhi Zhou, Haibo Li, Shuang Song, Lexi Ding, Xiaobo Xia
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Glaucoma is the leading cause of irreversible blindness. The progressive degeneration of retinal ganglion cells (RGCs) is the major characteristic of glaucoma. Even though the control of intraocular pressure could delay the loss of RGCs, current clin
Externí odkaz:
https://doaj.org/article/01699f35a291496dbe5b141e5c1b3db5
Publikováno v:
Biological Research, Vol 54, Iss 1, Pp 1-13 (2021)
Abstract Background Peroxisome proliferator-activated receptor alpha (PPARα) is associated with diabetic retinopathy (DR), and the underlying mechanism is still unclear. Aim of this work was to investigate the mechanism of PPARα in DR. Methods Huma
Externí odkaz:
https://doaj.org/article/bf5e38a43fce466090dd2ea882ee512b
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113378- (2022)
Objective: To investigate whether tert-Butylhydroquinone (TBHQ) can ameliorate oxidative stress and inflammation induced by glutamate excitotoxicity, and mediate retinal ganglion cell (RGC) damage by activating the nuclear factor erythroid 2-related
Externí odkaz:
https://doaj.org/article/cd2df3ddd15346f0bddb8bf0eb10e5a5
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundDiabetic retinopathy is a diabetic microvascular complication. Pyroptosis, as a way of inflammatory death, plays an important role in the occurrence and development of diabetic retinopathy, but its underlying mechanism has not been fully el
Externí odkaz:
https://doaj.org/article/6167746fade94f2d9153665c1684e284
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundDiabetic retinopathy (DR) is one of the most common microvascular complications of diabetes, which is associated with damage of blood-retinal barrier and ischemia of retinal vasculature. It devastates visual acuity due to leakage of retinal
Externí odkaz:
https://doaj.org/article/9fec7cdec9284c598c14c01379563cea
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Diabetic retinopathy (DR), a microvascular complication of diabetes mellitus, is the leading cause of vision loss in the working-age population worldwide. Unfortunately, current clinical treatments cannot completely prevent the occurrence and develop
Externí odkaz:
https://doaj.org/article/d3e569570138466ab1647330804270f5
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background and Objective: Retinal ischemia-reperfusion (IR) leads to massive loss of retinal ganglion cells (RGC) and characterizes several blind-causing ophthalmic diseases. However, the mechanism related to retinal IR is controversial, and a drug t
Externí odkaz:
https://doaj.org/article/7cacbbcb82264f02904ff98e26408cb9
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Myeloid cell leukemia 1 (Mcl1), an abundant protein in the myocardium, plays an essential role in fibrosis and anti-inflammation in cardiomyocytes to prevent heart failure. However, whether Mcl1 3′-untranslated regions (3′-UTR) has the cardio-pro
Externí odkaz:
https://doaj.org/article/da877b3a6fb941cebf4be99414cb7387
Autor:
Yan Xu, Changhan Ouyang, Dayin Lyu, Zhangmei Lin, Wencai Zheng, Fan Xiao, Zhimin Xu, Lexi Ding
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 125, Iss , Pp 109920- (2020)
Although diabetic nephropathy (DN) is induced by a complicate interplay of multiple factors, the underlying mechanisms remain poorly characterized, even the treatment. Herein, we show that both of DN patients and STZ-induced type 1 diabetic rat exhib
Externí odkaz:
https://doaj.org/article/e78739c135e6419483ecd058f608951f
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 5, Pp 2114-2122 (2018)
Background/Aims: In clinical settings, the pulsatility index (PI) has become a widely used tool for monitoring obstetrics or other vascular diseases. It is based on the maximum Doppler shift waveform derived from ultrasonography. However, it remains
Externí odkaz:
https://doaj.org/article/c7d589d3365341ee9f64140fa1a40def