Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids.

Autor: Zhao J; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA. zjing.0321@gmail.com.; Center for Regenerative Medicine, Neuroregeneration Laboratory, Mayo Clinic, Jacksonville, FL, 32224, USA. zjing.0321@gmail.com., Ikezu TC; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Lu W; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.; Center for Regenerative Medicine, Neuroregeneration Laboratory, Mayo Clinic, Jacksonville, FL, 32224, USA., Macyczko JR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Li Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Lewis-Tuffin LJ; Cytometry and Cell Imaging Laboratory, Mayo Clinic, Jacksonville, FL, USA., Martens YA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.; Center for Regenerative Medicine, Neuroregeneration Laboratory, Mayo Clinic, Jacksonville, FL, 32224, USA., Ren Y; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, 32224, USA., Zhu Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Asmann YW; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, 32224, USA., Ertekin-Taner N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA., Kanekiyo T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.; Center for Regenerative Medicine, Neuroregeneration Laboratory, Mayo Clinic, Jacksonville, FL, 32224, USA., Bu G; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA. Guojun.Bu@MolecularNeurodegeneration.org.; Center for Regenerative Medicine, Neuroregeneration Laboratory, Mayo Clinic, Jacksonville, FL, 32224, USA. Guojun.Bu@MolecularNeurodegeneration.org.

Publikováno v: Stem cell research & therapy [Stem Cell Res Ther] 2023 Aug 21; Vol. 14 (1), pp. 214. Date of Electronic Publication: 2023 Aug 21.

Substitution of PINK1 Gly411 modulates substrate receptivity and turnover.

Autor: Fiesel FC; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Neuroscience PhD Program, Mayo Graduate School of Biomedical Sciences, Mayo Clinic, Jacksonville, FL, USA., Fričová D; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Hayes CS; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Coban MA; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA., Hudec R; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Bredenberg JM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Broadway BJ; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Markham BN; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Yan T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Boneski PK; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Fiorino G; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Neuroscience PhD Program, Mayo Graduate School of Biomedical Sciences, Mayo Clinic, Jacksonville, FL, USA., Watzlawik JO; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Hou X; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., McCarty AM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Lewis-Tuffin LJ; Cytometry and Imaging Laboratory, Department of Research, Mayo Clinic, Jacksonville, FL, USA., Zhong J; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Madden BJ; Proteomics Core, Medical Genome Facility, Mayo Clinic, Rochester, MN, USA., Ordureau A; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., An H; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Puschmann A; Department of Neurology, Lund University, Skane University Hospital, Sweden., Wszolek ZK; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Ross OA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Neuroscience PhD Program, Mayo Graduate School of Biomedical Sciences, Mayo Clinic, Jacksonville, FL, USA., Harper JW; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Caulfield TR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Neuroscience PhD Program, Mayo Graduate School of Biomedical Sciences, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurosurgery, Mayo Clinic, Jacksonville, FL, USA., Springer W; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Neuroscience PhD Program, Mayo Graduate School of Biomedical Sciences, Mayo Clinic, Jacksonville, FL, USA.

Publikováno v: Autophagy [Autophagy] 2023 Jun; Vol. 19 (6), pp. 1711-1732. Date of Electronic Publication: 2022 Dec 05.

The AD tau core spontaneously self-assembles and recruits full-length tau to filaments.

Autor: Carlomagno Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Manne S; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., DeTure M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Prudencio M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA; Neuroscience Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA., Zhang YJ; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA; Neuroscience Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA., Hanna Al-Shaikh R; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Dunmore JA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Daughrity LM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Song Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Castanedes-Casey M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Lewis-Tuffin LJ; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA., Nicholson KA; Sean M. Healey and AMG Center for ALS, Massachusetts General Hospital (MGH), Boston, MA, USA., Wszolek ZK; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA; Neuroscience Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA., Fitzpatrick AWP; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Petrucelli L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA; Neuroscience Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA. Electronic address: petrucelli.leonard@mayo.edu., Cook CN; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA; Neuroscience Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA. Electronic address: cook.casey@mayo.edu.

Publikováno v: Cell reports [Cell Rep] 2021 Mar 16; Vol. 34 (11), pp. 108843.

Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2019 Conference Workshops.

Autor: Czechowska K; Altmattstrasse 1B, 6418, Rothenthurm, SZ, Switzerland., Lannigan J; Flow Cytometry Support Services, LLC, Alexandria, Virginia.; Flow Cytometry Core, University of Virginia, School of Medicine, Charlottesville, Virginia., Aghaeepour N; Department of Anesthesiology, Department of Biomedical Data Sciences, Department of Pediatrics, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford University, Stanford, California., Back JB; Department of Oncology, Wayne State University, Detroit, Michigan., Begum J; Flow Cytometry Facility, Barts Cancer Institute, Queen Mary University of London, London, UK., Behbehani G; Wexner Medical Center, Ohio State University, Columbus, Ohio., Bispo C; Parnassus Flow Cytometry Core, University of California San Francisco, San Francisco, California.; ISAC SRL Emerging Leader, Arlington, Virginia., Bitoun D; EMA Regional Marketing, BD Lifesciences, International Office, Belgium., Fernández AB; UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland., Boova ST; High Burden HIV Global Markets, Beckman Coulter, Inc., Miami, Florida., Brinkman RR; Medical Genetics, University of British Columbia and British Columbia Cancer, Vancouver, British Columbia, Canada.; Cytapex Bioinformatics Inc., Vancouver, British Columbia, Canada., Ciccolella CO; Omiq, Inc., Co-Founder and CEO, Santa Clara, California., Cotleur B; Biogen, Acute Neurology, Cambridge, Massachusetts., Davies D; Science Technology Platform Training Lead, Francis Crick Institute, London, UK., Dela Cruz GV; Novo Nordisk Foundation Center for Stem Cell Biology - DanStem, Flow Cytometry Platform, Copenhagen, Denmark., Del Rio-Guerra R; Flow Cytometry and Cell Sorting Facility, Larner College of Medicine, University of Vermont, Burlington, Vermont., Des Lauriers-Cox AM; Flow Cytometry Core Facility Assistant Manager, University of Michigan, Ann Arbor, Michigan., Douagi I; Flow Cytometry Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland., Dumrese C; Cytometry Facility, University of Zürich, Zürich, Switzerland., Bonilla Escobar DL; Immunology Department, MD Anderson Cancer Center, University of Texas, Houston, Texas., Estevam J; Center of Biomarker Innovation and Development, Takeda Pharmaceuticals, Cambridge, Massachusetts., Ewald C; Cytometry Facility Senior Scientist, University of Zürich, Zürich, Switzerland., Fossum A; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark., Gaudillière B; Anesthesiology Department, Stanford University, Stanford, California., Green C; Flow Cytometry Biomarkers Development Sciences, Genentech, Inc., San Francisco, California., Groves C; Cytometry/Dynamic Omics in R&D Antibody Discovery and Protein Engineering, Astra Zeneca, Gaithersburg, Maryland., Hall C; ISAC SRL Emerging Leader, Arlington, Virginia.; Cytometry Core Facility, Wellcome Sanger Institute, Hinxton, UK., Haque Y; Flow Cytometry Facility, Department of Immunobiology and Infectious Diseases, King's College London, London, UK., Hedrick MN; Clinical Flow Cytometry, Bristol-Myers Squibb, Princeton, New Jersey., Hogg K; Imaging and Cytometry Laboratory, Bioscience Technology Facility, Department of Biology, University of York, York, UK., Hsieh EWY; Department of Immunology and Microbiology, Department of Pediatrics, Division of Allergy and Immunology, School of Medicine, University of Colorado, Aurora, Colorado., Irish J; Cancer & Immunology Core and Mass Cytometry Center of Excellence, Vanderbilt University, Nashville, Tennessee., Lederer J; Department of Surgery (Immunology), Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts., Leipold M; Human Immune Monitoring Center (HIMC), Stanford University, Stanford, California., Lewis-Tuffin LJ; Microscopy and Flow Cytometry Shared Resource, Mayo Clinic, Jacksonville, Florida., Litwin V; Caprion Biosciences, Inc., Immunology, Montreal, Quebec, Canada., Lopez P; Cytometry and Cell Sorting Laboratory, New York University School of Medicine, New York, New York., Nasdala I; Sysmex Partec GmbH, Münster, Germany., Nedbal J; Physics Department, King's College London, London, UK.; ISAC Marylou Ingram Scholar, Arlington, Virginia., Ohlsson-Wilhelm BM; SciGro, Inc., North Central Office, Pittsburgh, Pennsylvania., Price KM; Hugh Green Cytometry Centre, Malaghan Institute of Medical Research, Wellington, New Zealand., Rahman AH; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, New York.; Dept. of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York., Rayanki R; Cytometry/Dynamic Omics in R&D Antibody Discovery and Protein Engineering, Astra Zeneca, Gaithersburg, Maryland., Rieger AM; ISAC SRL Emerging Leader, Arlington, Virginia.; University of Alberta, Flow Cytometry Facility, Faculty of Medicine and Dentistry, Alberta, Canada., Robinson JP; College of Veterinary Medicine and Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana., Shapiro H; One World Cytometry, Inc, Newton, Massachusetts., Sun YS; Clinical Flow Cytometry, Bristol-Myers Squibb, Princeton, New Jersey., Tang VA; University of Ottawa, Flow Cytometry and Virometry Core Facility, Ottawa, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada., Tesfa L; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York., Telford WG; Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Center Institute, National Institutes of Health, Bethesda, Maryland., Walker R; Flow Cytometry Core Facility, Babraham Institute, Cambridge, UK., Welsh JA; ISAC Marylou Ingram Scholar, Arlington, Virginia.; Laboratory of Pathology, Translational Nanobiology Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Wheeler P; Flow Cytometry, Luminex Corporation, Peterborough, UK., Tárnok A; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany.; Department Therapy Validation, Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.

Publikováno v: Cytometry. Part A : the journal of the International Society for Analytical Cytology [Cytometry A] 2019 Dec; Vol. 95 (12), pp. 1236-1274.