Zobrazeno 1 - 10
of 659
pro vyhledávání: '"Lewis Taylor"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2024)
Multiple studies have documented sex differences in sleep behaviour, however, the molecular determinants of such differences remain unknown. Furthermore, most studies addressing molecular mechanisms have been performed only in males, leaving the curr
Externí odkaz:
https://doaj.org/article/c5119e885553480ba73322abf7ea88c1
Autor:
Paul J N Brodersen, Hannah Alfonsa, Lukas B Krone, Cristina Blanco-Duque, Angus S Fisk, Sarah J Flaherty, Mathilde C C Guillaumin, Yi-Ge Huang, Martin C Kahn, Laura E McKillop, Linus Milinski, Lewis Taylor, Christopher W Thomas, Tomoko Yamagata, Russell G Foster, Vladyslav V Vyazovskiy, Colin J Akerman
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 1, p e1011793 (2024)
Electrophysiological recordings from freely behaving animals are a widespread and powerful mode of investigation in sleep research. These recordings generate large amounts of data that require sleep stage annotation (polysomnography), in which the da
Externí odkaz:
https://doaj.org/article/263fc5b386b345fe8fa91bf2ca6d9607
Autor:
Lewis Taylor, Steven Walsh, Anna Ashton, Norbert Varga, Sejal Kapoor, Charlotte George, Aarti Jagannath
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17362- (2023)
Whilst the regulation of chromatin accessibility and its effect on gene expression have been well studied in eukaryotic species, the role of chromatin dynamics and 3D organisation in genome reduced bacteria remains poorly understood [1,2]. In this st
Externí odkaz:
https://doaj.org/article/0d8df407371b4758b8f75dee635fd68f
Sleep and circadian rhythm disruption alters the lung transcriptome to predispose to viral infection
Autor:
Lewis Taylor, Felix Von Lendenfeld, Anna Ashton, Harshmeena Sanghani, Simona Di Pretoro, Laura Usselmann, Maria Veretennikova, Robert Dallmann, Jane A. McKeating, Sridhar Vasudevan, Aarti Jagannath
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105877- (2023)
Summary: Sleep and circadian rhythm disruption (SCRD), as encountered during shift work, increases the risk of respiratory viral infection including SARS-CoV-2. However, the mechanism(s) underpinning higher rates of respiratory viral infection follow
Externí odkaz:
https://doaj.org/article/a1abe26ff9904b94aa701cbd4db3ba41
Autor:
Aarti Jagannath, Simona Di Pretoro, Farid Ebrahimjee, Suzanne Ftouni, Lewis Taylor, Russell G. Foster, Sridhar Vasudevan
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Circadian entrainment in mice relies primarily on photic cues that trigger the transcription of the core clock genes Period1/2 in the suprachiasmatic nucleus (SCN), thus aligning the phase of the clock with the dawn/dusk cycle. It has been shown prev
Externí odkaz:
https://doaj.org/article/ba0c1419819a4e2d91bfd343c20b5f49
Autor:
M.ª Concepción Bravo Guerreira, Teodoro Hampe Martínez, Franklin Pease, Carlos Sempat Assadourian, Fernando Iwasaki, Eduardo Dargent Chamot, José de la Puente Brunke, Tierry Saignes, Teresa Cañedo-Argüelles Fábrega, Peter T. Bradley, Guillermo Lohmann Villena, Luis Jaime Cisneros, Pedro Guibovich, Kendall W. Brown, Serena Fernádez Alonso, John Fisher, Jose Miguel Medrano, Carlos Malamud, José Antonio García Vera, David P. Cahill, Marie-Laure Rieu-Millán, Carlos Contreras, Rory Miller, Lewis Taylor, James Higgins, Ignacio González
Publikováno v:
Revista de Indias, Vol 48, Iss 182-183 (2022)
Externí odkaz:
https://doaj.org/article/6ecf589d5df34549bf47552ab823b36c
Autor:
Aarti Jagannath, Norbert Varga, Robert Dallmann, Gianpaolo Rando, Pauline Gosselin, Farid Ebrahimjee, Lewis Taylor, Dragos Mosneagu, Jakub Stefaniak, Steven Walsh, Teele Palumaa, Simona Di Pretoro, Harshmeena Sanghani, Zeinab Wakaf, Grant C. Churchill, Antony Galione, Stuart N. Peirson, Detlev Boison, Steven A. Brown, Russell G. Foster, Sridhar R. Vasudevan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Sleep pressure and circadian rhythms influence one another. However, the regulatory mechanisms are unclear. Here, the authors show that adenosine A1/A2A receptor antagonists, such as caffeine, shift circadian rhythms and enhance the effects of light,
Externí odkaz:
https://doaj.org/article/fe29a732cf334692a98923abc1d068d8
Autor:
Daniel Regan-Komito, Sophia Valaris, Theodore S. Kapellos, Carlota Recio, Lewis Taylor, David R. Greaves, Asif J. Iqbal
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Chemerin is a chemotactic protein that induces migration of several immune cells including macrophages, immature dendritic cells, and NK cells. Chemerin binds to three G protein-coupled receptors (GPCRs), including CCRL2. The exact function of CCRL2
Externí odkaz:
https://doaj.org/article/c63fe218aa85402990b09b3dfccf6c7c