Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Lewis S. Schanker"'
Autor:
Judith A. Hemberger, Lewis S. Schanker
Publikováno v:
Neonatology. 40:99-104
The effect of cortisone (5 mg/animal i.p. on day 5 after birth) on the development of adult-type permeability characteristics in the lung was investigated in rats 6–18 days of age. In both treated and control rats, the lipid-soluble drug procainami
Autor:
I. Antonowicz, Stefano Cutillo, M C Elphick, H. Shwachman, George C. Emmanouilides, David Harvey, György Csaba, Judith A. Hemberger, Christine E. Parkinson, R.S. Everts, John H. Shand, Lewis S. Schanker, Donald W. Thibeault, H. Havinga, Fred G. Smith, John Moore, M.E. Weichsel, Ganesh Supramaniam, Jean E. Robillard, F.A. Hommes, J.G. Lecce, Rachele Corti, Bengt I. Ingvarsson, Roy Jones, J.O. Rundell, Börje W. Karlsson, S. U. Nagy, Russell E. Poland, David Hull, Tullio Meloni, S. Ishida, Michael E. Dodge, Raymond C. Noble, Brian R. Clark, Christine Sessions, Sinfarosa Costa, Roland Carlsson, J.L. Edson
Publikováno v:
Neonatology. 34:I-IV
Autor:
Lewis S. Schanker, Jerry A. Burton
Publikováno v:
Xenobiotica. 4:291-296
1. Pulmonary absorption half-times (min) in the rat for four sulphonamides and three antitubercular drugs were: sulphadimethoxine
Autor:
Lewis S. Schanker, Judith A. Hemberger
Publikováno v:
Neonatology. 34:299-303
The effect of thyroxine (1–2 μg/g i.p. on days 1–4 after birth) on development of adult-type permeability characteristics in the lung was investigated in rats 6–18 days of age. In both treated and control rats, the lipid-soluble drug procaine
Autor:
Thomas H. Gardiner, Lewis S. Schanker
Publikováno v:
Xenobiotica. 4:725-731
1. Pulmonary absorption studies in the rat with 0–01–100 mM solutions of disodium cromoglycate (DSCG) indicated that absorption occurred in part by a saturable, carrier-type transport process and in part by diffusion.2. Carrier transport became s
Autor:
Yi-Jong Lin, Lewis S. Schanker
Publikováno v:
Biochemical Pharmacology. 30:2937-2943
Uptake of amino acids by rat lung slices was investigated using the 14 C-labeled nonmetabolized foreign compounds 1-aminocyclopentanecarboxylic acid (cycloleucine) and α-aminoisobutyric acid (AIB). When incubated with slices suspended in oxygenated
Autor:
Lewis S. Schanker, Jerry A. Burton
Publikováno v:
Experimental Biology and Medicine. 152:377-380
SummarySolutions of heparin and cyanocobalamin were administered through a tight-fitting tracheal cannula into the lungs of anesthetized rats. The times necessary for 50% absorption from the lungs were 3 hr for cyanocobalamin and 9.2 hr for heparin.
Autor:
Thomas H. Gardiner, Lewis S. Schanker
Publikováno v:
Experimental Biology and Medicine. 149:972-977
SummaryTo investigate the effect of a papain-induced emphysema-like condition on pulmonary absorption of drugs, rats were exposed to either papain aerosol or distilled water aerosol (control) intermittently for 2 wk, and rates of drug absorption from
Autor:
Lewis S. Schanker, Shang W. Hwang
Publikováno v:
Environmental Research. 7:206-211
To investigate the pulmonary and intestinal absorption of the insecticide carbaryl (1-naphthyl-N-methylcarbamate; Sevin), solutions of the compound (0.005–0.1 m m ) were administered into the lungs or small intestine of anesthetized rats. After var
Autor:
Thomas H. Gardiner, Lewis S. Schanker
Publikováno v:
Experimental Biology and Medicine. 151:288-292
SummaryTo investigate the effect of paraquat-induced lung damage on pulmonary absorption of drugs, rats were given a single oral dose of paraquat (250 mg/kg), and rates of drug absorption from damaged and control lungs were compared after various tim