Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lewis R. Makings"'
Autor:
Tom Knapp, Victor Panchenko, Paul A. Negulescu, Ashvani K. Singh, Roger D. Tung, James A. Rader, Timothy Neuberger, Fredrick Van Goor, Kimberly Straley, Jeffrey H. Stack, Jesus E. Gonzalez, Eric R. Olson, John Joubran, Dong Cao, Mark Miller, Peter D. J. Grootenhuis, Sabine Hadida, Anna R. Hazlewood, Lewis R. Makings
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 290:L1117-L1130
Cystic fibrosis (CF) is a fatal genetic disease caused by mutations in cftr, a gene encoding a PKA-regulated Cl−channel. The most common mutation results in a deletion of phenylalanine at position 508 (ΔF508-CFTR) that impairs protein folding, tra
Autor:
Lewis R. Makings, Alexander A. Krasnovsky, Thomas A. Moore, Paul A. Liddell, Ana L. Moore, Devens Gust, Peter J. Pessiki, Janice M. DeGraziano, David E. Nicodem, Pamela K. Kerrigan
Publikováno v:
Journal of the American Chemical Society. 115:5684-5691
In the reaction centers of photosynthetic organisms, chlorophyll triplet states are sometimes formed by recombination of charge-separated intermediates. These triplets are excellent sensitizers for singlet oxygen formation. Carotenoid polyenes can pr
Autor:
Lewis R. Makings, Edith Bittersmann, Ana L. Moore, Frans C. De Schryver, Michel Rougee, Thomas A. Moore, Xiaochun C. Ma, Seung Joo Lee, Devens Gust, Janice M. DeGraziano, René V. Bensasson, Susanne Woodward, David K. Luttrull, Feng Gao, Mark Van der Auweraer, Gilbert R. Seely, Todd T. Trier
Publikováno v:
Journal of the American Chemical Society. 113:3638-3649
A variety of molecular triads and dyads consisting of covalently linked carotenoid (C) andor porphyrin (P) moieties have been prepared and studied with transient absorption and time-resolved fluorescence techniques. Diporphyrins of the type P A -P B
Autor:
Lewis R. Makings, Thomas A. Moore, Gregory A. Nemeth, Paul A. Liddell, Ana L. Moore, Devens Gust
Publikováno v:
Journal of the American Chemical Society. 108:8028-8031
Excitation of carotenoid-porphyrin-quinone (C-P-Q) triad molecules initiates a two-step electron transfer to yield a final charge separated state of the form C·+-P-Q·-.
Autor:
Devens Gust, Thomas A. Moore, Barry W. Chadwick, Paul A. Liddell, Lewis R. Makings, Richard J. Cogdell, Harry A. Frank, Jung Jin Oh, Ana L. Moore
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 892:253-263
Triplet state electron spin resonance (ESR) spectroscopy has been used to study triplet-triplet energy transfer in B800–850 light-harvesting complexes and carotenoporphyrin molecules. The B800–850 complexes were isolated from the photosynthetic b
Autor:
Lewis R. Makings, Michel Rougee, Doris Lexa, Devens Gust, René V. Bensasson, F. C. De Schryver, Thomas A. Moore, Peter J. Pesski, Ana L. Moore, Susan Hatlevig, M. Van der Auweraer
Publikováno v:
Israel Journal of Chemistry. 28:87-95
Carotenoporphyrin-quinone triad molecules have previously been found to successfully mimic many aspects of photosynthetic electron and energy transfer. These molecules generate long-lived, energetic charge-separated states via a biomimetic multistep
Autor:
René V. Bensasson, Paul A. Liddell, Lewis R. Makings, Ana L. Moore, Devens Gust, Gregory A. Nemeth, Donna Barrett, Peter J. Pessiki, Thomas A. Moore
Publikováno v:
Journal of the American Chemical Society. 109:846-856
Carotenoid-porphyrin-quinone triad molecules undergo a photodriven two-step electron-transfer reaction which results in the generation of a high-energy charge-separated state with a lifetime on the microsecond time scale at ambient temperatures in fl
Publikováno v:
Neuron. (2):407-415
The role of nitric oxide (NO) in the induction of longterm depression (LTD) in the cerebellum was explored using a new, organic, membrane-impermeant form of caged NO. NO photolytically released inside Purkinje neurons mimicked parallel fiber (PF) act
Publikováno v:
Chemistry & Biology. (9):765-774
Background : Fluorescent indicators that show alterations in excitation and/or emission spectra in response to changes in [Ca 2+ ] are widely used for quantitative cytosolic [Ca 2+ ] measurements. There are several reports of changes in apparent [Ca
Autor:
Devens Gust, Gilbert R. Seely, Ana L. Moore, Feng Gao, Lewis R. Makings, Todd T. Trier, Xiaochun. Ma, Thomas A. Moore
Publikováno v:
Journal of the American Chemical Society. 110:7567-7569
A four-component molecular device, which consists of two covalently linked porphyrins, one bearing a carotenoid polyene and the other a napthoquinone electron-acceptor, has been prepared to attempt to explain the electron-transfer strategy of photosy