Zobrazeno 1 - 10 of 295 pro vyhledávání: '"Lewis Phillips G"'
1
Akademický článek
Trastuzumab does not bind rat or mouse ErbB2/neu: implications for selection of non-clinical safety models for trastuzumab-based therapeutics.
Autor: Lewis Phillips G; Department of Discovery Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. phillips.gail@gene.com., Guo J; Department of Discovery Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Kiefer JR; Department of Structural Biology, Genentech, Inc., South San Francisco, CA, USA., Proctor W; Department of Safety Assessment, Genentech, Inc., South San Francisco, CA, USA., Bumbaca Yadav D; Department of Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Merck & Co, Inc., South San Francisco, CA, USA., Dybdal N; Department of Safety Assessment, Genentech, Inc., South San Francisco, CA, USA., Shen BQ; Department of Preclinical and Translational Pharmacokinetics, Genentech, Inc., South San Francisco, CA, USA.
Publikováno v: Breast cancer research and treatment [Breast Cancer Res Treat] 2022 Jan; Vol. 191 (2), pp. 303-317. Date of Electronic Publication: 2021 Oct 27.
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3
Akademický článek
Antibody-mediated delivery of chimeric protein degraders which target estrogen receptor alpha (ERα).
Autor: Dragovich PS; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: dragovich.peter@gene.com., Adhikari P; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Blake RA; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Blaquiere N; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Chen J; WuXi AppTec, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Cheng YX; Pharmaron Beijing, Co. Ltd., BDA Beijing, 6 Tai He Road, 100176, China., den Besten W; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Han J; Pharmaron Beijing, Co. Ltd., BDA Beijing, 6 Tai He Road, 100176, China., Hartman SJ; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., He J; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., He M; Pharmaron Beijing, Co. Ltd., BDA Beijing, 6 Tai He Road, 100176, China., Rei Ingalla E; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Kamath AV; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Kleinheinz T; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Lai T; WuXi AppTec, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Leipold DD; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Li CS; WuXi AppTec, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Liu Q; Pharmaron Beijing, Co. Ltd., BDA Beijing, 6 Tai He Road, 100176, China., Lu J; WuXi Biologics, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Lu Y; WuXi AppTec, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Meng F; Pharmaron Beijing, Co. Ltd., BDA Beijing, 6 Tai He Road, 100176, China., Meng L; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Ng C; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Peng K; WuXi Biologics, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Lewis Phillips G; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Pillow TH; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Rowntree RK; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Sadowsky JD; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Sampath D; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Staben L; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Staben ST; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Wai J; WuXi AppTec, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Wan K; WuXi AppTec, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Wang X; WuXi AppTec, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Wei B; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Wertz IE; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Xin J; Pharmaron Beijing, Co. Ltd., BDA Beijing, 6 Tai He Road, 100176, China., Xu K; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Yao H; WuXi AppTec, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Zang R; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Zhang D; Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA., Zhou H; WuXi AppTec, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China., Zhao Y; WuXi AppTec, Waigaoqiao Free Trade Zone, 288 Fute Zhong Road, Shanghai 200131, China.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Feb 15; Vol. 30 (4), pp. 126907. Date of Electronic Publication: 2019 Dec 18.
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4
Akademický článek
Exploration of Pyrrolobenzodiazepine (PBD)-Dimers Containing Disulfide-Based Prodrugs as Payloads for Antibody-Drug Conjugates.
Autor: Pei Z; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Chen C; WuXi Biologics, 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Chen J; Wuxi Apptec , 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Cruz-Chuh JD; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Delarosa R; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Deng Y; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Fourie-O'Donohue A; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Figueroa I; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Guo J; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Jin W; WuXi Biologics, 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Khojasteh SC; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Kozak KR; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Latifi B; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Lee J; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Li G; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Lin E; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Liu L; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Lu J; WuXi Biologics, 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Martin S; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Ng C; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Nguyen T; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Ohri R; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Lewis Phillips G; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Pillow TH; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Rowntree RK; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Stagg NJ; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Stokoe D; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Ulufatu S; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Verma VA; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Wai J; Wuxi Apptec , 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Wang J; Wuxi Apptec , 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Xu K; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Xu Z; Wuxi Apptec , 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Yao H; Wuxi Apptec , 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Yu SF; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Zhang D; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Dragovich PS; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
Publikováno v: Molecular pharmaceutics [Mol Pharm] 2018 Sep 04; Vol. 15 (9), pp. 3979-3996. Date of Electronic Publication: 2018 Aug 06.
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5
Akademický článek
Conjugation of Indoles to Antibodies through a Novel Self-Immolating Linker.
Autor: Dragovich PS; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Blake RA; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Chen C; WuXi Biologics, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, P. R. China., Chen J; WuXi Apptec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, P. R. China., Chuh J; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., den Besten W; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Fan F; WuXi Apptec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, P. R. China., Fourie A; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Hartman SJ; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., He C; WuXi Apptec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, P. R. China., He J; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Ingalla ER; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Kozak KR; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Leong SR; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Lu J; WuXi Biologics, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, P. R. China., Ma Y; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Meng L; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Nannini M; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Oeh J; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Ohri R; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Lewis Phillips G; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Pillow TH; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Rowntree RK; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Sampath D; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Vandlen R; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Vollmar B; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Wai J; WuXi Apptec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, P. R. China., Wertz IE; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Xu K; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Xu Z; WuXi Apptec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, P. R. China., Zhang D; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2018 Apr 03; Vol. 24 (19), pp. 4830-4834. Date of Electronic Publication: 2018 Mar 25.
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6
Akademický článek
New-generation advanced PROTACs as potential therapeutic agents in cancer therapy.
Autor: Wang, Chao1 (AUTHOR), Zhang, Yujing2 (AUTHOR) yujingzhang666@163.com, Chen, Wujun1 (AUTHOR), Wu, Yudong1 (AUTHOR) wuyudong@qdu.edu.cn, Xing, Dongming1,3 (AUTHOR) xdm_tsinghua@163.com
Publikováno v: Molecular Cancer. 5/21/2024, Vol. 23 Issue 1, p1-41. 41p.
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8
Akademický článek
Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells.
Autor: Junttila TT; Genentech, Inc., South San Francisco, California. junttila.teemu@gene.com., Li J; Genentech, Inc., South San Francisco, California., Johnston J; Genentech, Inc., South San Francisco, California., Hristopoulos M; Genentech, Inc., South San Francisco, California., Clark R; Genentech, Inc., South San Francisco, California., Ellerman D; Genentech, Inc., South San Francisco, California., Wang BE; Genentech, Inc., South San Francisco, California., Li Y; Genentech, Inc., South San Francisco, California., Mathieu M; Genentech, Inc., South San Francisco, California., Li G; Genentech, Inc., South San Francisco, California., Young J; Genentech, Inc., South San Francisco, California., Luis E; Genentech, Inc., South San Francisco, California., Lewis Phillips G; Genentech, Inc., South San Francisco, California., Stefanich E; Genentech, Inc., South San Francisco, California., Spiess C; Genentech, Inc., South San Francisco, California., Polson A; Genentech, Inc., South San Francisco, California., Irving B; Genentech, Inc., South San Francisco, California., Scheer JM; Genentech, Inc., South San Francisco, California., Junttila MR; Genentech, Inc., South San Francisco, California., Dennis MS; Genentech, Inc., South San Francisco, California., Kelley R; Genentech, Inc., South San Francisco, California., Totpal K; Genentech, Inc., South San Francisco, California., Ebens A; Genentech, Inc., South San Francisco, California.
Publikováno v: Cancer research [Cancer Res] 2014 Oct 01; Vol. 74 (19), pp. 5561-71. Date of Electronic Publication: 2014 Sep 16.
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9
Akademický článek
Self‐Assembled L–DNA Linkers for Rapid Construction of Multi‐Specific Antibody‐Drug Conjugates Library.
Autor: Zhou, Liujuan1 (AUTHOR), Yang, Fan2 (AUTHOR) kooyang@aliyun.com, Bai, Zhaoshuai1 (AUTHOR), Zhou, Xiaohui3 (AUTHOR), Zhang, Zhihai2 (AUTHOR), Li, Zhihang1 (AUTHOR), Gong, Junyuan3 (AUTHOR), Yu, Junqi1 (AUTHOR), Pan, Liqiang4 (AUTHOR), Cao, Chan3 (AUTHOR) chancao@nankai.edu.cn, Chou, James J.5 (AUTHOR)
Publikováno v: Angewandte Chemie. 7/3/2023, Vol. 135 Issue 27, p1-9. 9p.
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10
Akademický článek
HER2低表达乳腺癌新辅助化疗效果及其预后 特征：一项单中心回顾性研究.
Autor: 王若曦1, 吉  芃1, 龚  悦1, 陈  盛1 0456177@fudan.edu.cn
Publikováno v: China Oncology. Jul2023, Vol. 33 Issue 7, p686-692. 7p.
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