Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lewis Lanier"'
Autor:
Frederic Preffer, Jack Dunne, Diether Recktenwald, Andrew Blidy, Lewis Lanier, Joe Trotter, Michael J. Daley
Publikováno v:
Cytometry. Part B, Clinical cytometry.
Autor:
Wei Cao, Jingjing Li, Xinfang Huang, Stephanie Dorta-Estremera, Jeremy Di Domizio, Scott Anthony, Kimberly Schluns, Lewis Lanier
Publikováno v:
The Journal of Immunology. 194:115.2-115.2
The mechanism by which plasmacytoid dendritic cells (pDCs) promote humoral autoimmunity is unclear. In amyloid-induced experimental autoimmune model, pDC activation is accompanied by prominent neutrophilia. We investigated the contribution of neutrop
Autor:
Vanessa York, Jeffrey Milush, Sandra López-Vergès, Steven Deeks, Jeffrey Martin, Frederick Hecht, Lewis Lanier, Douglas Nixon
Publikováno v:
The Journal of Immunology. 190:206.6-206.6
A subset of CD3negCD56negCD16+ Natural Killer (NK) cells is highly expanded during chronic HIV-1 infection, and the role of this subset in HIV-1 pathogenesis remains unclear. The lack of NK cell lineage-specific markers has complicated the study of m
Publikováno v:
The Journal of Immunology. 190:189.4-189.4
Respiratory viral infections, including parainfluenza virus (PIV), are a significant cause of illness and death worldwide, especially among young children and the elderly. Understanding the immune response to these viruses is important for reducing p
Autor:
Yosuke Kamimura, Lewis Lanier
Publikováno v:
The Journal of Immunology. 190:173.6-173.6
Previously, only T and B cells were thought able to generate long-lived memory cells; however, recent studies demonstrated that natural killer (NK) cells expressing the activating Ly49H receptor undergo clonal expansion, contraction, and generate lon
Publikováno v:
The Journal of Immunology. 190:173.7-173.7
Apoptosis is critical in lymphocyte development and homeostasis; moreover, this pathway eliminates activated lymphocytes and prevents immune pathology during viral infection. Pro-apoptotic factor Bim controls LCMV-specific T cell contraction and the
Autor:
Tsukasa Nabekura, Lewis Lanier
Publikováno v:
The Journal of Immunology. 190:173.5-173.5
Recent studies have demonstrated that natural killer (NK) cells have adaptive immune features including antigen-specific expansion and subsequent generation of a memory subset. However, the precise signaling pathways that promote the expansion and th
Publikováno v:
The Journal of Immunology. 190:183.11-183.11
NKG2D is an activating receptor expressed by all Natural Killer (NK) cells, a subset of T cells, and activated macrophages. NKG2D and its ligands, which are expressed on stressed or damaged cells, play important roles during viral infections, cancers
Publikováno v:
The Journal of Immunology. 188:115.7-115.7
Natural killer (NK) cells and CD8+ T cells function similarly in the recognition and destruction of host cells infected with pathogens. Although microRNAs (miRs) are critical for NK and T cell development and function, the role of specific miRs remai
Autor:
K Mark Ansel, Molly Thomas, Sarah Abdul-Wajid, Marisella Panduro, Joshua Babiarz, Misha Rajaram, Prescott Woodruff, Lewis Lanier, Vigo Heissmeyer
Publikováno v:
The Journal of Immunology. 188:115.9-115.9
Natural killer (NK) cells play a critical role in early host defense to infected and transformed cells. Here we show that mice deficient in Eri1, a conserved 3’-to-5’ exoribonuclease that represses RNA interference, have a cell-intrinsic defect i