Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lewis L Truex"'
Publikováno v:
Journal of Clinical Toxicology.
Objective: The transforming growth factor β (TGF-β) pathway regulates diverse cellular functions and plays a prominent role in diseases such as cancer, autoimmune disorders and cardiovascular disease. LY2157299 monohydrate (LY2157299) is a potent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d71f13c8c57564bc54c7d61f2b38462d
https://doi.org/10.4172/2161-0495.196
https://doi.org/10.4172/2161-0495.196
Autor:
David O. Calligaro, Foreman Mark Mortensen, Kris Eckols, Julie F. Falcone, Virginia L. Lucaites, Neil W. DeLapp, David L. Nelson, Lewis L. Truex, Frank P. Bymaster
Publikováno v:
Schizophrenia Research. 37:107-122
The atypical antipsychotic olanzapine has relatively high affinity for a number of neuronal receptors in radioreceptor binding assays. The ability of olanzapine to activate or antagonize a number of neuronal receptors was investigated in vitro, in ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c452c818dc90c0b9835ac63129bc287
https://doi.org/10.1016/s0920-9964(98)00146-7
https://doi.org/10.1016/s0920-9964(98)00146-7
Autor:
David F. Wozniak, J. Phillip Miller, Melanie McEwen, John W. Olney, Lewis L. Truex, Andrew S. Fix
Publikováno v:
Brain research. 696(1-2)
A single dose of the non-competitive NMDA receptor antagonist MK-801 (dizocilpine maleate) induces neuronal necrosis in the posterior cingulate/retrosplenial (PC/RS) cortex of adult rats. The present studies further characterized this effect and eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9633fb7da985fdffc07c634bbbf3b10
https://pubmed.ncbi.nlm.nih.gov/8574669
https://pubmed.ncbi.nlm.nih.gov/8574669
Publikováno v:
Acta neuropathologica. 88(6)
Cytoplasmic vacuoles appear in neurons of the posterior cingulate/retrosplenial cortex (PC/RS) of rats after treatment with N-methyl-d-aspartate (NMDA) receptor antagonists. Prominent dilatation of mitochondria and endoplasmic reticulum has been desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51541df5e28909d67cedde2fad4972f4
https://pubmed.ncbi.nlm.nih.gov/7879597
https://pubmed.ncbi.nlm.nih.gov/7879597
Publikováno v:
Journal of Neurochemistry. 31:427-431
— The components of the cyclic nucleotide system were studied in rat brain at various times after death to determine the stability of the system postmortem. The concentration of cyclic AMP in 4 brain regions was highest 10 min after death and decli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a63d4ccb77535d82e4074a73bda2c1
https://doi.org/10.1111/j.1471-4159.1978.tb02658.x
https://doi.org/10.1111/j.1471-4159.1978.tb02658.x
Publikováno v:
Journal of Neurochemistry. 32:335-344
— The activity of soluble protein kinase and phosphorylation of endogenous synaptosomal proteins were studied in vitro, in the hippocampus and cerebral cortex of rats 3, 12, or 24 months of age. No between-age differences in the activity of cyclic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14076be33472a4f6f5e7f2a43c38c11d
https://doi.org/10.1111/j.1471-4159.1979.tb00356.x
https://doi.org/10.1111/j.1471-4159.1979.tb00356.x
Autor:
Lewis L. Truex, Robert M. Riggs, Foreman Mark Mortensen, Ann T. McKenzie, David E. Nichols, Stephen R. Byrn
Publikováno v:
Journal of Medicinal Chemistry. 30:1914-1918
beta-Methyldopamine and its enantiomers and racemic beta-phenyldopamine were synthesized and evaluated for dopamine D-1 agonist activity. In the dopamine-sensitive adenylate cyclase assay, beta-phenyldopamine had about one-sixth the activity of dopam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121735d0fe8a380509757b8ed2e2af5f
https://doi.org/10.1021/jm00393a039
https://doi.org/10.1021/jm00393a039
Publikováno v:
Journal of Neuroscience Research. 6:789-801
The Purkinje cell degeneration mutant (pcd) is characterized by a complete loss of cerebellar Purkinje cells. Norepinephrine causes an accumulation of cyclic AMP in the cerebellum of pcd that is far greater than in normal mice. Experiments were condu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7a707b9a277f78a549a3323fcb857f
https://doi.org/10.1002/jnr.490060613
https://doi.org/10.1002/jnr.490060613
Autor:
Michael J. Schmidt, Lewis L. Truex
Publikováno v:
Neurobiology of Aging. 1:93-95
The distribution of amphetamine in the brain, liver, and fat of 3-month-old Wistar rats was compared to the distribution in 24-month-old rats. Animals were killed 20 or 65 min after the IP administration of 2.5 mg/kg of 3 H-amphetamine. Amphetamine l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5c15921571b2ac93c484edda88ebfe
https://doi.org/10.1016/0197-4580(80)90029-9
https://doi.org/10.1016/0197-4580(80)90029-9
Autor:
Lewis L. Truex, Robert M. Riggs, Jai D. Kohli, David E. Nichols, Foreman Mark Mortensen, Dana Glock
Publikováno v:
ChemInform. 19
The title compounds were prepared and examined to elucidate further the structure-activity relationships of dopamine agonists related to nomifensine. Two of the compounds, 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline and 4-(3,4-dihydroxyphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb5e43cc0a3c69d21ad579953e29449f
https://doi.org/10.1002/chin.198806178
https://doi.org/10.1002/chin.198806178