Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lewis Grozinger"'
Publikováno v:
Microbial Biotechnology, Vol 16, Iss 3, Pp 546-559 (2023)
Abstract Synthetic biology uses molecular biology to implement genetic circuits that perform computations. These circuits can process inputs and deliver outputs according to predefined rules that are encoded, often entirely, into genetic parts. Howev
Externí odkaz:
https://doaj.org/article/3193a051bc8542ecb40b76248da8b378
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Genetic circuits can be engineered to generate predefined outcomes, however host context is a crucial factor in performance. Here the authors characterise twenty NOT gates in seven different bacteria to understand and predict interoperability and por
Externí odkaz:
https://doaj.org/article/cc80afe3b1d048be9b7194d29717c1e4
Autor:
Lewis Grozinger, Martyn Amos, Thomas E. Gorochowski, Pablo Carbonell, Diego A. Oyarzún, Ruud Stoof, Harold Fellermann, Paolo Zuliani, Huseyin Tas, Angel Goñi-Moreno
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Synthetic biology uses cells as its computing substrate, often based on the genetic circuit concept. In this Perspective, the authors argue that existing synthetic biology approaches based on classical models of computation limit the potential of bio
Externí odkaz:
https://doaj.org/article/299394da6ed34fa1a1a67b8fdcfad878
Autor:
Esteban Martínez-García, Sofía Fraile, Elena Algar, Tomás Aparicio, Elena Velázquez, Belén Calles, Huseyin Tas, Blas Blázquez, Bruno Martín, Clara Prieto, Lucas Sánchez-Sampedro, Morten H H Nørholm, Daniel C Volke, Nicolas T Wirth, Pavel Dvořák, Lorea Alejaldre, Lewis Grozinger, Matthew Crowther, Angel Goñi-Moreno, Pablo I Nikel, Juan Nogales, Víctor de Lorenzo
Publikováno v:
Martínez-García, E, Fraile, S, Algar, E, Aparicio, T, Velázquez, E, Calles, B, Tas, H, Blázquez, B, Martín, B, Prieto, C, Sánchez-Sampedro, L, Nørholm, M H H, Volke, D C, Wirth, N T, Dvořák, P, Alejaldre, L, Grozinger, L, Crowther, M, Goñi-Moreno, A, Nikel, P I, Nogales, J & de Lorenzo, V 2023, ' SEVA 4.0: an update of the Standard European Vector Architecture database for advanced analysis and programming of bacterial phenotypes ', Nucleic Acids Research, vol. 51, no. D1, pp. D1558–D1567 . https://doi.org/10.1093/nar/gkac1059
The SEVA platform (https://seva-plasmids.com) was launched one decade ago, both as a database (DB) and as a physical repository of plasmid vectors for genetic analysis and engineering of Gram-negative bacteria with a structure and nomenclature that f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f1b039e447131b2ad3fae697ca1df4
https://orbit.dtu.dk/en/publications/4e321df4-ea29-4104-8b3f-a08b9154a3a8
https://orbit.dtu.dk/en/publications/4e321df4-ea29-4104-8b3f-a08b9154a3a8
Special Issue: Microbial electrochemical technologies and Synthetic Biology. 14 Pág.
Synthetic biology uses molecular biology to implement genetic circuits that perform computations. These circuits can process inputs and deliver outputs accordi
Synthetic biology uses molecular biology to implement genetic circuits that perform computations. These circuits can process inputs and deliver outputs accordi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa78bc83140b73f92c3fc43ce2ea5c4
http://hdl.handle.net/10261/310948
http://hdl.handle.net/10261/310948
Synthetic biology uses molecular biology to implement genetic circuits that perform computations. These circuits can process inputs and deliver outputs according to predefined rules that are encoded, often entirely, into genetic parts. However, the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e73aa52a7c964b03c10c82561ef22b02
https://doi.org/10.1101/2022.05.19.492718
https://doi.org/10.1101/2022.05.19.492718
Publikováno v:
Synthetic Biology
Boolean NOR gates have been widely implemented in Escherichia coli as transcriptional regulatory devices for building complex genetic circuits. Yet, their portability to other bacterial hosts/chassis is generally hampered by frequent changes in the p
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The implementation of Boolean logic circuits in cells have become a very active field within synthetic biology. Although these are mostly focussed on the genetic components alone, the context in which the circuit performs is crucial for its outcome.
MotivationMeasuring fluorescence by flow cytometry is fundamental for characterising single-cell performance. While it is known that fluorescence and scattering values tend to positively correlate, the impact of cell volume on fluorescence is typical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f308b832bc63dc032a3f10732084a94
https://doi.org/10.1101/2020.07.23.217869
https://doi.org/10.1101/2020.07.23.217869
Autor:
Anil Wipat, Lewis Grozinger, Jacob Beal, Bryan Bartley, Goksel Misirli, Angel Goñi-Moreno, Matthew Crowther, Matthew Pocock, Christopher P. D. Taylor, James Alastair McLaughlin
Publikováno v:
ACS Synthetic Biology
The Synthetic Biology Open Language (SBOL) is an emerging synthetic biology data exchange standard, designed primarily for unambiguous and efficient machine-to-machine communication. However, manual editing of SBOL is generally difficult for non-triv